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E A Rogaeva S Premkumar J Grubber L Serneels W K Scott T Kawarai Y Song D L Hill S M Abou-Donia E R Martin J J Vance G Yu A Orlacchio Y Pei M Nishimura A Supala B Roberge A M Saunders A D Roses D Schmechel A Crane-Gatherum S Sorbi A Bruni G W Small P M Conneally J L Haines F Van Leuven P H St George-Hyslop L A Farrer M A Pericak-Vance 《Nature genetics》1999,22(1):19-22
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基于一篇文章所引用的参考文献和该文的被引频次两个维度,提出了衡量该文外显成长度的相对指标.该研究涉及的引用数据及每条参考文献的被引数据均来自网络版科学引文索引(Web of Science),检索日期为2010年4月最后一周. 相似文献
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Summary Literature concerning the impacts of acidification on the phytoplankton and zooplankton composition has been reviewed. Available data on the species richness and composition of phytoplankton, attached algae and zooplankton of acidifying systems have been summarized. The effects of water acidification on the primary productivity and biomass of zooplankton have been discussed. 相似文献
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R. S. E. W. Leuven C. den Hartog M. M. C. Christiaans W. H. C. Heijligers 《Cellular and molecular life sciences : CMLS》1986,42(5):495-503
Summary Nine amphibian species were encountered in poorly buffered waters of The Netherlands (alkalinity 1 meq·l–1). These soft water systems are highly sensitive to acidifying precipitation. The number of species as well as the percentage of waters which harbour amphibian populations are strongly reduced in the extremely acid pH-class
. The reproductive success of amphibians is negatively affected by low pH. The eggs become heavily infested with fungi (Saprolegniaceae). In acidifying systems many physico-chemical parameters are significantly correlated with the pH of the water. Strongly acidified waters are characterized by low alkalinity, conductivity and ionic content but high acidity and high concentrations of (heavy) metals and ammonium and a high relative sulphate concentration. Culture experiments with eggs and larvae ofRana arvalis. Rana esculenta, Rana temporaria andBufo bufo show that apart from the pH, elevated aluminium, cadmium and ammonium contents may also affect the reproductive success of amphibians. 相似文献
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Gerald F. Shields Brooke A. Christiaens Michelle L. Van Leuven Amber L. Hartman 《西北部美国博物学家》2011,69(4)
We made 27 collections over nine years at the Clearwater River and conducted preliminary cytogenetic analysis on 232 individuals of the Simulium arcticum complex there. Based on these preliminary findings, we analyzed an additional 1825 larvae from Clearwater collections in 2007, 2008, and 2009 to investigate the reproductive statuses of the two prevalent taxa of the complex there and to determine whether cytogenetic diversity and frequency of types were similar from year to year. We describe a cytotype new to science and a potentially derivative cytotype of S. arcticum sensu stricto. We also determine that these two taxa are present in similar frequencies from year to year and are in genetic equilibrium, suggesting that they are not reproductively isolated. This study constitutes the fourth positive test of our Geographic Distribution/Taxon Age hypothesis. 相似文献
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Jaworski T Dewachter I Lechat B Gees M Kremer A Demedts D Borghgraef P Devijver H Kügler S Patel S Woodgett JR Van Leuven F 《Nature》2011,480(7376):E4-5; discussion E6
Arising from C. J. Phiel, C. A. Wilson, V. M.-Y. Lee & P. S. Klein 423, 435-439 (2003)A major unresolved issue in Alzheimer's disease is identifying the mechanisms that regulate proteolytic processing of amyloid precursor protein (APP)-glycogen synthase kinase-3 (GSK-3) isozymes are thought to be important in this regulation. Phiel et al. proposed that GSK-3α, but not GSK-3β, controls production of amyloid. We analysed the proteolytic processing of mouse and human APP in mouse brain in vivo in five different genetic and viral models. Our data do not yield evidence for either GSK-3α-mediated or GSK-3β-mediated control of APP processing in brain in vivo. 相似文献
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