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Vasodilator nerve fibres to the submaxillary gland of the cat 总被引:2,自引:0,他引:2
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Schachter M. Barton Susanne Karpinski E. 《Cellular and molecular life sciences : CMLS》1973,29(12):1498-1499
Zusammenfassung Die «Nacherweiterung» der Gefässe, welche auf Reizung des sympathischen Nervs der Submaxillaris-Drüse in der Katze folgt, wird nicht durch Kallikrein oder Kinin ausgelöst, da sie nicht durch den hochwirksamen synthetischen Bradykinin-potenzierenden Faktors (BPF) beeinflusst wird. Eine neue Beobachtung zeigte, dass diese sympathische Gefässerweiterung bedeutend verstärkt wird, nachdem der parasympathische Nerv durchschnitten wurde und degeneriert ist.
This work was supported by grants from the Medical Research Council of Canada and the Alberta Heart Foundation. 相似文献
This work was supported by grants from the Medical Research Council of Canada and the Alberta Heart Foundation. 相似文献
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The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide. 相似文献
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M. Schachter Susanne Barton M. Uddin E. Karpinski E. J. Sanders 《Cellular and molecular life sciences : CMLS》1977,33(6):746-748
Summary Various procedures which reduce or deplete the kallikrein content of the cat's submandibular gland correspondingly reduce the number of apical granules in the striated duct cells. The kallikrein content is greatly reduced after chronic parasympathetic but not after sympathetic nerve section which suggests that the parasympathetic innervation is required for synthesis or storage of this enzyme.We wish to acknowledge the valuable assistance of Dr T. Nihei and Mr. J. Wimal in some of the enzyme measurements.This work was supported by grants from the Medical Research Council of Canada and the Alberta Heart Foundation. 相似文献
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A bradykinin analogue, D-Arg[Hyp3, Thi5,8, D-Phe7]-Bk, antagonized the vasodilator effect of bradykinin injected close-arterially in the submandibular salivary gland of the cat, without affecting that due to acetylcholine or nerve stimulation. The same analogue also antagonized the hypotensive response to bradykinin injected intravenously in cats and rabbits. We conclude that functional hyperaemia in the submandibular gland of the cat is not due to the release of bradykinin by salivary kallikrein. 相似文献
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M. Schachter Susanne Barton E. Karpinski 《Cellular and molecular life sciences : CMLS》1973,29(8):973-974
Zusammenfassung Nachweis, dass bei Reizung des N. chorda lingualis der Katze ein Blutdruckeffekt ausbleibt, wenn ein Bradykinin potenzierender Faktor (Präparat BPF) zuvor gegeben wurde.
Acknowledgments. We are greatly indepted to Dr.J. Stewart of the University of Colorado and to Dr.L. Greene of Brookhaven National Laboratories, New York, for kind gifts of synthetic bradykinin potentiators.
This work was supported by grants from the Medical Research Council of Canada and the Alberta Heart Foundation. 相似文献
Acknowledgments. We are greatly indepted to Dr.J. Stewart of the University of Colorado and to Dr.L. Greene of Brookhaven National Laboratories, New York, for kind gifts of synthetic bradykinin potentiators.
This work was supported by grants from the Medical Research Council of Canada and the Alberta Heart Foundation. 相似文献
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S. Barton E. Karpinski M. Schachter 《Cellular and molecular life sciences : CMLS》1988,44(10):897-898
Summary A bradykinin analogue, D-Arg[Hyp3, Thi5, 8, D-Phe7]-Bk, antagonized the vasodilator effect of bradykinin injected close-arterially in the submandibular salivary gland of the cat, without affecting that due to acetylcholine or nerve stimulation. The same analogue also antagonized the hypotensive response to bradykinin injected intravenously in cats and rabbits. We conclude that functional hyperaemia in the submandibular gland of the cat is not due to the release of bradykinin by salivary kallikrein. 相似文献
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