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Summary Mouse embryos were exposed to various doses of cadmium and/or X-rays on day 8 of gestation. The combined treatment exerted an antagonistic effect regarding the teratogenic action of the two agents. 相似文献
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Summary The short-time restraint of pregnant mice on day 8 of gestation led to a significant increase of the anomaly rate in fetuses. This effect may be due to stress factors of endocrine origin.The technical assistance of Mrs E. Frei is gratefully acknowledged. Supported by the Swiss National Foundation for Scientific Research. 相似文献
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Mutations-induction followed by selection is a suitable method for developing a cell line with resistance to low doses of X-rays. In comparison with the original cell line, the derived resistant line is characterized by an enhanced variability of the chromosome number, and no higher level of cellular repair, limited to the two repair types described. 相似文献
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Methaemoglobinbildung durch Röntgenstrahlen in normalen und katalasefreien Erythrocyten des Menschen
Summary Methaemoglobin-formation in irradiated human red cells largely depends on catalase activity in either phase of the system. The formation rate is low in normal, but high in acatalatic cells. The latter rate can be lowered to normal by adding 0.1 /ml catalase to the suspending medium. 相似文献
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The short-time restraint of pregnant mice on day 8 of gestation led to a significant increase of the anomaly rate in fetuses. This effect may be due to stress factors of endocrine origin. 相似文献
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I. Balla C. Michel Hedi Fritz-Niggli 《Cellular and molecular life sciences : CMLS》1981,37(10):1105-1106
Summary The eye region of mouse embryos, irradiated with 90 rad X-rays on day 8 of gestation, was examined 24 h later for cellular damage. Besides the overall developmental retardation, the radiation insult decreased the proliferation rate and altered the mitotic phase ratio. Due to the limited extension of necrotic zones, a reduced number of dead cells was found in the irradiated optic vesicles.Supported by the Swiss National Foundation for Scientific Research. The technical assistance of Mrs E. Frei is gratefully acknowledged. 相似文献
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Summary Valium® anaesthesia significantly reduces the effect of large single doses of X-rays on the mouse foot skin as compared with Nembutal® anaesthesia. The radioprotective action of Valium may be attributed to a direct effect on the cells of the skin.Supported by the Swiss National Science Foundation (Grant no. 3.682-0.75).Acknowledgments. The authors wish to thank Miss F.T. Josuran, Miss U. Schärer and Mr P.P. Binz for their excellent technical assistance with the experiments. 相似文献