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The Ror receptor tyrosine kinase family 总被引:6,自引:0,他引:6
Forrester WC 《Cellular and molecular life sciences : CMLS》2002,59(1):83-96
Receptor tyrosine kinases (RTKs) participate in numerous developmental decisions. Ror RTKs are a family of orphan receptors
that are related to muscle specific kinase (MuSK) and Trk neurotrophin receptors. MuSK assembles acetylcholine receptors at
the neuromuscular junction [1, 2], and Trk receptors function in the developing nervous system (reviewed in [3-5]). Rors have
been identified in nematodes, insects and mammals. Recent studies have begun to shed light on Ror function during development.
In most species, Rors are expressed in many tissue types during development. Analyses of mutants that are defective in the
single nematode Ror demonstrate a role in cell migration and in orienting cell polarity. Mice lacking one of the two Ror gene
products display defects in bone and heart formation. Similarly, two different human bone development disorders, dominant
brachydactyly B and recessive Robinow syndrome, result from mutations in one of the human Ror genes.
Received 17 April 2001; received after revision 2 July 2001; accepted 4 July 2001 相似文献
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A. R. Forrester 《Cellular and molecular life sciences : CMLS》1984,40(7):688-689
Summary Aqueous solutions of hermidin readily give rise to a blue transient radical-anion on exposure to air, the identity of which has been established by ESR spectroscopy.Acknowledgment. I thank Professor R. H. Thomson for helpful discussion. 相似文献
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Histones and cancer test 总被引:1,自引:0,他引:1
E W Johns J A Pritchard J L Moore W H Sutherland C A Joslin J A Forrester A J Davies A M Neville R G Fish 《Nature》1973,245(5420):98-99
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Changes in surface charge of HeLa cells during the cell cycle 总被引:1,自引:0,他引:1
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Scanning electron microscopy of healing wounds 总被引:1,自引:0,他引:1
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RNAse A mismatch cleavage analysis of 66 primary human colon tumors reveals a high incidence of K-ras genes with mutations at position 12. No apparent correlation was found between the presence of mutant oncogenes and the degree of invasiveness of the tumours but evidence for ras mutational activation in premalignant tissue was obtained. 相似文献
10.
Alan Forrester 《Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics》2007,38(4):815-831
In recent papers, Zurek [(2005). Probabilities from entanglement, Born's rule pk=|ψk|2 from entanglement. Physical Review A, 71, 052105] has objected to the decision-theoretic approach of Deutsch [(1999) Quantum theory of probability and decisions. Proceedings of the Royal Society of London A, 455, 3129–3137] and Wallace [(2003). Everettian rationality: defending Deutsch's approach to probability in the Everett interpretation. Studies in History and Philosophy of Modern Physics, 34, 415–438] to deriving the Born rule for quantum probabilities on the grounds that it courts circularity. Deutsch and Wallace assume that the many worlds theory is true and that decoherence gives rise to a preferred basis. However, decoherence arguments use the reduced density matrix, which relies upon the partial trace and hence upon the Born rule for its validity. Using the Heisenberg picture and quantum Darwinism—the notion that classical information is quantum information that can proliferate in the environment pioneered in Ollivier et al. [(2004). Objective properties from subjective quantum states: Environment as a witness. Physical Review Letters, 93, 220401 and (2005). Environment as a witness: Selective proliferation of information and emergence of objectivity in a quantum universe. Physical Review A, 72, 042113]—I show that measurement interactions between two systems only create correlations between a specific set of commuting observables of system 1 and a specific set of commuting observables of system 2. This argument picks out a unique basis in which information flows in the correlations between those sets of commuting observables. I then derive the Born rule for both pure and mixed states and answer some other criticisms of the decision theoretic approach to quantum probability. 相似文献