排序方式: 共有1条查询结果,搜索用时 0 毫秒
1
1.
Domiziana Costamagna Mattia Quattrocelli Robin Duelen Vardine Sahakyan Ilaria Perini Giacomo Palazzolo Maurilio Sampaolesi 《Cellular and molecular life sciences : CMLS》2014,71(4):615-627
Regenerative medicine for skeletal and cardiac muscles still constitutes a fascinating and ambitious frontier. In this perspective, understanding the possibilities of intrinsic cell plasticity, present in post-natal muscles, is vital to define and improve novel therapeutic strategies for acute and chronic diseases. In addition, many somatic stem cells are now crossing the boundaries of basic/translational research to enter the first clinical trials. However, it is still an open question whether a lineage switch between skeletal and cardiac adult myogenesis is possible. Therefore, this review focuses on resident somatic stem cells of post-natal skeletal and cardiac muscles and their plastic potential toward the two lineages. Furthermore, examples of myogenic lineage switch in adult stem cells are also reported and discussed. 相似文献
1