排序方式: 共有28条查询结果,搜索用时 78 毫秒
1.
F. V. DeFeudis L. M. Orensanz Muñoz M. A. Vidal G. Corrochano M. Sanchez del Alamo 《Cellular and molecular life sciences : CMLS》1978,34(9):1169-1170
Summary High-affinity, Na+-independent binding of -alanine to a synaptosomal fraction of rat brain was potently inhibited by glycine and by some other -amino acids, but not by taurine or GABA. This binding mechanism, which was also sensitive to both bicuculline and strychnine, might involve synaptic receptors for both -alanine and glycine.This study was supported in part by Centro Ramón y Cajal and Fundacion Juan March. 相似文献
2.
F V DeFeudis L M Orensanz Mu?oz M A Vidal G Corrochano M Sanchez del Alamo 《Experientia》1978,34(9):1169-1170
High-affinity, Na+-independent binding of beta-alanine to a synaptosomal fraction of rat brain was potently inhibited by glycine and by some other alpha-amino acids, but not by taurine or GABA. This binding mechanism, which was also sensitive to both bicuculline and strychnine, might involve synaptic receptors for both beta-alanine and glycine. 相似文献
3.
F V DeFeudis 《Experientia》1978,34(10):1314-1315
Bicuculline- and strychnine-sensitive components of the binding of GABA, glycine and beta-alanine, which can be demonstrated in the presence of a physiological concentration of Na+, might be related to synaptic receptors. 相似文献
4.
F. V. DeFeudis 《Cellular and molecular life sciences : CMLS》1978,34(10):1314-1315
Summary Bicuculline- and strychnine-sensitive components of the binding of GABA, glycine and -alanine, which can be demonstrated in the presence of a physiological concentration of Na+, might be related to synaptic receptors. 相似文献
5.
Summary The difference in protein of cerebral nerve-ending fractions caused by differential housing of male mice is of a quantitative nature and might reflect a change in the number of nerve-endings.This work was supported in part by Centro Nacional Ramón y Cajal (de la Seguridad Social) and Fundación Juan March and was conducted in part at the Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan Italy, while Dr F. P. Conde was on a research fellowship. Thanks are due to Mr Riccardo Gelati for technical assistance and to Mr Mario Azzini for the photography. 相似文献
6.
7.
γ-Aminobutyric acid and cardiovascular function 总被引:1,自引:0,他引:1
F. V. DeFeudis 《Cellular and molecular life sciences : CMLS》1983,39(8):845-849
8.
Summary In a model of conditioned feeding behavior, oral administration of cyproheptadine (1–100 mg/kg), 30 min before presentation of food, produced a dose-dependent reduction of food intake in the rat (ED5017 mg/kg during the 1st h of testing). This anorexic effect persisted for at least 24 h. These results provide further evidence that under certain conditions cyproheptadine, which is used as an orectic agent in man, can produce anorexia. 相似文献
9.
F. V. DeFeudis P. Madtes J. Gervas-Camacho 《Cellular and molecular life sciences : CMLS》1977,33(3):340-342
Summary GABA (6×10–6 M) binding to synaptosome-enriched fractions of cat CNS exhibited a clear rostro-caudal gradient, whereas glycine (6×10–6 M) binding was greatest to particles of cerebellar cortex, and this was followed by medulla caudate nucleus cerebral cortex pons > corona radiata. Strychnine-SO4 (10–3 or 10–4 M) inhibited the binding of GABA and glycine in all brain regions studied; at 10–5 M this drug inhibited the binding of both GABA and glycine only to particles of the cerebral cortex.This study was supported by Centro Nacional Ramón y Cajal and Fundación Juan March. P. M. was a summer student from Eastern Nazarene College, Wollaston, Mass., USA. 相似文献
10.