The effect of acidic polysaccharides and prostaglandin-like substances isolated from Propionibacterium acnes on granulocyte chemotaxis.

Three acidic polysaccharide (AP) fractions and the prostaglandin-like substances (PLS) isolated from P. acnes were investigated regarding their chemotactic activities on polymorphonuclear leukocytes. Both AP's and PLS induced a significant chemotatic response, which suggests their involvement in inflammatory acne vulgaris.     

The effect of acidic polysaccharides and prostaglandin-like substances isolated fromPropionibacterium acnes on granulocyte chemotaxis

Summary Three acidic polysaccharide (AP) fractions and the prostaglandin-like substances (PLS) isolated fromP. acnes were investigated regarding their chemotactic activities on polymorphonuclear leukocytes. Both AP's and PLS induced a significant chemotactic response, which suggests their involvement in inflammatory acne vulgaris.