排序方式: 共有16条查询结果,搜索用时 281 毫秒
1.
复数,实数及实对称数据下Bruun FFT算法的实现 总被引:3,自引:0,他引:3
本文在复数、实数以及实对称数据下研究和实现了Bruun FFT算法。文章分析和评价了各种数据下BruunFFT的运算量和特点,提出了算法的实现结构和方法。最后给了TMS320C30上的运算时间,我们实现的算法比基2FFT速度提高35%。 相似文献
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SongTing Shi David J. J. de Gorter Willem M. H. Hoogaars Peter A. C. ’t Hoen Peter ten Dijke 《Cellular and molecular life sciences : CMLS》2013,70(3):407-423
Bone morphogenetic proteins (BMPs) are important extracellular cytokines that play critical roles in embryogenesis and tissue homeostasis. BMPs signal via transmembrane type I and type II serine/threonine kinase receptors and intracellular Smad effector proteins. BMP signaling is precisely regulated and perturbation of BMP signaling is connected to multiple diseases, including musculoskeletal diseases. In this review, we will summarize the recent progress in elucidation of BMP signal transduction, how overactive BMP signaling is involved in the pathogenesis of heterotopic ossification and Duchenne muscular dystrophy, and discuss possible therapeutic strategies for treatment of these diseases. 相似文献
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西部农业信息化建设问题的探讨 总被引:3,自引:0,他引:3
西部农业信息化水平低下制约着西部农业的发展。物质基础薄弱、信息意识淡薄、信息人才及资金短缺是造成西部农业信息化水平低下的原因。为加快西部信息化农业建设,应该从更新观念、加大政府支持力度、利用有限资源进行信息化基础建设、重视人才资源的开发、培育信息产品市场、加强农业应用系统和信息化农业技术的研究、加强示范应用体系等方面入手。 相似文献
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Singh R Hoogaars WM Barnett P Grieskamp T Rana MS Buermans H Farin HF Petry M Heallen T Martin JF Moorman AF 't Hoen PA Kispert A Christoffels VM 《Cellular and molecular life sciences : CMLS》2012,69(8):1377-1389
A key step in heart development is the coordinated development of the atrioventricular canal (AVC), the constriction between the atria and ventricles that electrically and physically separates the chambers, and the development of the atrioventricular valves that ensure unidirectional blood flow. Using knock-out and inducible overexpression mouse models, we provide evidence that the developmentally important T-box factors Tbx2 and Tbx3, in a functionally redundant manner, maintain the AVC myocardium phenotype during the process of chamber differentiation. Expression profiling and ChIP-sequencing analysis of Tbx3 revealed that it directly interacts with and represses chamber myocardial genes, and induces the atrioventricular pacemaker-like phenotype by activating relevant genes. Moreover, mutant mice lacking 3 or 4 functional alleles of Tbx2 and Tbx3 failed to form atrioventricular cushions, precursors of the valves and septa. Tbx2 and Tbx3 trigger development of the cushions through a regulatory feed-forward loop with Bmp2, thus providing a mechanism for the co-localization and coordination of these important processes in heart development. 相似文献
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Gene expression profiling predicts clinical outcome of breast cancer 总被引:243,自引:0,他引:243
van 't Veer LJ Dai H van de Vijver MJ He YD Hart AA Mao M Peterse HL van der Kooy K Marton MJ Witteveen AT Schreiber GJ Kerkhoven RM Roberts C Linsley PS Bernards R Friend SH 《Nature》2002,415(6871):530-536
Breast cancer patients with the same stage of disease can have markedly different treatment responses and overall outcome. The strongest predictors for metastases (for example, lymph node status and histological grade) fail to classify accurately breast tumours according to their clinical behaviour. Chemotherapy or hormonal therapy reduces the risk of distant metastases by approximately one-third; however, 70-80% of patients receiving this treatment would have survived without it. None of the signatures of breast cancer gene expression reported to date allow for patient-tailored therapy strategies. Here we used DNA microarray analysis on primary breast tumours of 117 young patients, and applied supervised classification to identify a gene expression signature strongly predictive of a short interval to distant metastases ('poor prognosis' signature) in patients without tumour cells in local lymph nodes at diagnosis (lymph node negative). In addition, we established a signature that identifies tumours of BRCA1 carriers. The poor prognosis signature consists of genes regulating cell cycle, invasion, metastasis and angiogenesis. This gene expression profile will outperform all currently used clinical parameters in predicting disease outcome. Our findings provide a strategy to select patients who would benefit from adjuvant therapy. 相似文献
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't Hooft G Susskind L Witten E Fukugita M Randall L Smolin L Stachel J Rovelli C Ellis G Weinberg S Penrose R 《Nature》2005,433(7023):257-259
8.
Gallagher FA Kettunen MI Day SE Hu DE Ardenkjaer-Larsen JH Zandt Ri Jensen PR Karlsson M Golman K Lerche MH Brindle KM 《Nature》2008,453(7197):940-943
As alterations in tissue pH underlie many pathological processes, the capability to image tissue pH in the clinic could offer new ways of detecting disease and response to treatment. Dynamic nuclear polarization is an emerging technique for substantially increasing the sensitivity of magnetic resonance imaging experiments. Here we show that tissue pH can be imaged in vivo from the ratio of the signal intensities of hyperpolarized bicarbonate (H(13)CO(3)(-)) and (13)CO(2) following intravenous injection of hyperpolarized H(13)CO(3)(-). The technique was demonstrated in a mouse tumour model, which showed that the average tumour interstitial pH was significantly lower than the surrounding tissue. Given that bicarbonate is an endogenous molecule that can be infused in relatively high concentrations into patients, we propose that this technique could be used clinically to image pathological processes that are associated with alterations in tissue pH, such as cancer, ischaemia and inflammation. 相似文献
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潘江 《科技情报开发与经济》2004,14(6):9-10
引入研究型大学及其图书馆的定义,阐述了研究型大学图书馆进行人力资源管理的重要意义。进而提出了研究型大学图书馆人力资源管理的策略,包括改变人力资源管理理念,建立以人为本的人才管理机制,注重人才的使用和培养,充分调动馆员的积极性等。 相似文献
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庞晓青 《科技情报开发与经济》2004,14(6):250-251
人才是提高综合国力的关键要素。为用好人才,一是要辨证地把握好识别人才、起用人才的标准,既要选拔出德才兼备的人才,又不可求全责备;二是用人要讲究方法。做到公平竞争、择优录用、知人善用,同时鼓励人才合理流动;三是用人要遵循讲正气、讲民主、讲大度的原则,大胆使用人才。 相似文献