The ‘Società degli Spettroscopisti Italiani’: birth and evolution

The anniversary of the death of Pietro Tacchini (1838–1905), one of the pioneers of solar physics in Italy, is commemorared by this account of his major creation, the Società degli Spettroscopisti Italiani (1871). Established to promote cooperation among solar spectroscopists engaged in the study of the solar chromosphere, it was the first scientific Society devoted to spectroscopy and its astronomical applications. Its journal, the Memorie, collected most of the important works on solar physics by Angelo Secchi SJ (1818–1878), Tacchini himself, and many other protagonists of the newly born astrophysics. A brief history of the Society and its development draws on many previously unexploited archival sources, in order to show its role in raising astrophysics to the status of a scientific discipline, in the context of the astronomical research of that time in Italy and abroad, especially in the USA.     

Mutations in CEP290, which encodes a centrosomal protein, cause pleiotropic forms of Joubert syndrome

Joubert syndrome-related disorders (JSRD) are a group of syndromes sharing the neuroradiological features of cerebellar vermis hypoplasia and a peculiar brainstem malformation known as the 'molar tooth sign'. We identified mutations in the CEP290 gene in five families with variable neurological, retinal and renal manifestations. CEP290 expression was detected mostly in proliferating cerebellar granule neuron populations and showed centrosome and ciliary localization, linking JSRDs to other human ciliopathies.