Characterization of the Expression of CTRP9, a Paralog of Adiponectin

Adiponectin is one of the hormones secreted exclusively by the adipose tissue with anti-diabetic anti-inflammatory, anti-atherogenic, anti-atherosclerotic, and insulin-sensitizing effects. Adiponectin has structural features including a signal peptide at the N terminus, a short variable region, a collagenous domain, and a C-terminal globular domain homologous to Clq. The family of proteins containing this globular domain is called the C1q/tumor necrosis factor-a-related proteins （CTRP）. Among all the CTRPs characterized so far, the CTRP9 protein has the highest homology to adiponectin. However, little is known about the functions of CTRP9. This study examines the tissue expression of CTRP9 as well as the expression of CTRP9 during mouse development and 3T3-L1 preadipocyte differentiation. The effects of LPS, TNFα, and starvation on the expression of CTRP9 were also investigated. CTRP9 mRNA is shown to be expressed in a variety of tissues including the adipose tissues. The expression profile of CTRP9 differs from that of adiponectin, implying that they are functionally diverse although structurally homologous.     

防腐蒸球的研制与展望

８０年代初期,造纸行业大多采用碱法制浆,碱法制浆对蒸球的腐蚀比较轻微,蒸球爆炸的事故较少。然而,碱法制浆对环境的污染很严重,威胁着人类的生存。 ８０年代末期,造纸行业陆续采用亚铵法制浆．虽然缓解了对环境的污染问题,但是却对球壳的化学腐蚀和冲刷磨损量很大。据有关研究统计资料,亚铵法制浆对碳钢蒸球的腐蚀与磨损速率约２－３ｍｍ／年。所以,在造纸行业兴盛的８０年代末期到９０年代初期,造纸蒸球爆炸事故频繁发生,成为我省事故率最高的压力容器。据我省１９８７年－１９９８年的事故报告统计,有２５台造纸蒸球发生了…     

组合优化聚类与马尔科夫链的城市环卫车辆行驶工况构建方法

为客观描述城市环卫车的实际行驶特征,基于3辆市政环卫车连续一周实际道路行驶数据,提出一种组合优化聚类与马尔科夫链的城市环卫车辆行驶工况构建方法. 首先对特征参数矩阵做均值化处理,增强参数降维后每一个主成分中所包含的特征参数信息;其次利用k均值聚类将不同运行特征的运动学片段划分到不同类的样本集内,以马尔科夫链法在每一类样本集中做状态预测,按时间比例合成代表工况. 最后,基于运动学参数对所构建的代表工况进行有效性检验. 结果表明,所构建的福州市环卫车辆行驶工况相较于C-WTVC国家标准工况,能更客观地反映福州市环卫车辆的实际运行情况.