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Program evaluation can support capacity building and inform practice and policy. Yet long-term efforts to ensure evaluation use (EU) in the humanitarian sector are seldom documented, leaving much uncertainty about EU conditions. This study examined conditions that influenced EU by stakeholders of a humanitarian non-governmental organization (NGO) in Burkina Faso striving to base its health care program on solid evidence. It used 36 qualitative semi-structured interviews and a single case study design to document stakeholders’ (n?=?26) perception of EU conditions. Analyses focussed on characteristics of five broad conditions of research use previously documented. Results demonstrate that EU was facilitated by intended users with proactive attitudes, research experience, and willingness to participate in program evaluations. Also helpful was an organizational culture that valued learning, feedback, and accountability, wherein leaders collaborated toward common goals. Evaluation-based knowledge that met information needs and that was actionable, contextualized, and quickly accessible enhanced EU. Knowledge transfer strategies promoting EU were diverse, participatory, adapted to needs, and regularly followed up. Evaluators who were trusted, experienced, credible, and adaptable, promoted EU most effectively. Conversely, EU was compromised when intended users felt distrusting, uninformed, or unable to engage in program evaluations. Knowledge contradicting expectations or deemed inapplicable impeded EU. Adapting knowledge transfer strategies required time and interactions. Initially, evaluations were not sufficiently adapted and put into plain language, which hampered EU. EU conditions are numerous and intricately interrelated, but interpersonal relationships, trust, and effective communication are key conditions for evaluators and stakeholders wishing to promote EU.

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