基于整数线性规划的MPSoC通信优化策略

摘要： 针对多处理器片上系统 (Multiprocessor System on chip,MPSoC) 的通信优化技术--通信流水线和消息聚合,其过度使用可能会导致系统同步开销上升从而带来整体系统性能降低的问题,提出了基于整数线性规划(Integer Linear Programming, ILP)的优化策略.该策略以综合优化系统通信和同步开销为目标,通过对通信流水线技术和消息聚合技术的合理规划,使系统性能达到最优.实验结果表明,基于ILP的通信优化策略能够充分发挥通信优化技术的优点,使系统性能显著提升.
关键词： 通信优化; 整数线性规划; Simulink
中图分类号： TP 31文献标志码： A     

医疗无线传感器网络匿名认证机制

针对无线医疗传感器网络的特点,以智能卡和口令作为身份认证与密钥交换的基础,提出了一种匿名认证机制,主要包括注册、登陆、认证以及口令更新4个阶段.该机制可以保证专业人员及其病人的匿名性,实现传感器节点与专业人员之间的双向认证以及网关、传感器节点、专业人员之间的公平的密钥协商;与此同时,利用静态Diffie-Hellman密钥、会话密钥对传输过程的相关信息进行加密,保证其机密性.     

颗粒级配对火山灰力学特性影响的试验研究

以吉林省靖宇县的黑色、红色两种火山灰为原材料,分别配制了5种不同级配的试样.通过土粒相对密度、矿物成分与颗粒形态、直接剪切和固结试验分析,得到该火山灰材料的土粒相对密度、化学成分、颗粒形态、剪切强度、压缩性等物理力学特性,并分析了5种级配的中值粒径d50和不均匀系数cu对火山灰剪切强度的影响.靖宇火山灰主要由泡沫状的火山玻璃组成,未经历过长期水力、风力的磨圆作用,颗粒棱角分明,其剪切特性与干沙土类似,内聚力很小,剪切强度受级配的影响较大.在配制的5种级配曲线的粒径范围,试样的内摩擦角随着中值粒径d50的增大而增大,不均匀系数cu对试样内摩擦角的影响较小.     

Positive regulation of apoptosis signal-regulating kinase 1 by dual-specificity phosphatase 13A

Apoptosis signal-regulating kinase 1 (ASK1), a member of the MAP kinase kinase kinase, is activated by several death stimuli and is tightly regulated by several mechanisms such as interactions with regulatory proteins and post-translational modifications. Here, we report that dual-specificity phosphatase 13A (DUSP13A) functions as a novel regulator of ASK1. DUSP13A interacts with the N-terminal domain of ASK1 and induces ASK1-mediated apoptosis through the activation of caspase-3. DUSP13A enhances ASK1 kinase activity and thus its downstream factors. Small interfering RNA (siRNA) analyses show that knock-down of DUSP13A in human neuroblastoma SK-N-SH cells reduces ASK1 kinase activity. The phosphatase activity of DUSP13A is not required for the regulation of ASK1. This regulatory action of DSUP13 on ASK1 activity involves competition with Akt1, a negative regulator of ASK1, for binding to ASK1. Taken together, this study provides novel insights into the role of DUSP13A in the precise regulation of ASK1.     

Chaperonin-mediated stabilization and ATP-triggered release of semiconductor nanoparticles

Various properties of semiconductor nanoparticles, including photoluminescence and catalytic activity, make these materials attractive for a range of applications. As nanoparticles readily coagulate and so lose their size-dependent properties, shape-persistent three-dimensional stabilizers that enfold nanoparticles have been exploited. However, such wrapping approaches also make the nanoparticles insensitive to external stimuli, and so may limit their application. The chaperonin proteins GroEL (from Escherichia coli) and T.th ('T.th cpn', from Thermus thermophilus HB8) encapsulate denatured proteins inside a cylindrical cavity; after refolding, the encapsulated proteins are released by the action of ATP inducing a conformational change of the cavity. Here we report that GroEL and T.th cpn can also enfold CdS semiconductor nanoparticles, giving them high thermal and chemical stability in aqueous media. Analogous to the biological function of the chaperonins, the nanoparticles can be readily released from the protein cavities by the action of ATP. We expect that integration of such biological mechanisms into materials science will open a door to conceptually new bioresponsive devices.     

半平面上有限级B值Dirichlet级数的增长性

研究了有关B值Dirichlet级数的一些基本性质,扩充了B值Dirichlet级数的理论.在此基础上,研究了B值Dirichlet级数的增长级,得到了正规增长的几个充分必要条件.     

广义 Korteweg-de Vries-Burgers 方程解的一致估计

考查了广义Korteweg-de Vries-Burgers方程ut f(u)x=μuxx δuxxx的Cauchy问题解的一致估计。粗略地讲就是Korteweg-de Vries-Burgers方程是无粘Burgers方程的一个粘性逼近。     

DESIGN OF A SOFTWARE AGENT FOR BUSINESS GAMING SIMULATION

1. Introduction 1.1 Gaming Simulation Gaming Simulation is categorized into the following five fields: Entertainment games, Educational games, Experimental games, Research games, and Operational games (Stahl, 1983). Business game is one of the Educational games. Business game is a tool that focuses on understanding about business and the principle of management through the experience in a virtual world. Through this method the players have roles of managers or presidents of companies (Ter…     

CD24 controls Src/STAT3 activity in human tumors

CD24 is a glycosyl-phosphatidylinositol-anchored membrane protein that is frequently over-expressed in a variety of human carcinomas and is correlated with poor prognosis. In cancer cell lines, changes of CD24 expression can alter several cellular properties in vitro and tumor growth in vivo. However, little is known about how CD24 mediates these effects. Here we have analyzed the functional consequences of CD24 knock-down or over-expression in human cancer cell lines. Depletion of CD24 reduced cell proliferation and adhesion, enhanced apoptosis, and regulated the expression of various genes some of which were identified as STAT3 target genes. Loss of CD24 reduced STAT3 and FAK phosphorylation. Diminished STAT3 activity was confirmed by specific reporter assays. We found that reduced STAT3 activity after CD24 knock-down was accompanied by altered Src phosphorylation. Silencing of Src, similar to CD24, targeted the expression of prototype STAT3-regulated genes. Likewise, the over-expression of CD24 augmented Src-Y416 phosphorylation, the recruitment of Src into lipid rafts and the expression of STAT3-dependent target genes. An antibody to CD24 was effective in reducing tumor growth of A549 lung cancer and BxPC3 pancreatic cancer xenografts in mice. Antibody treatment affected the level of Src-phosphorylation in the tumor and altered the expression of STAT3 target genes. Our results provide evidence that CD24 regulates STAT3 and FAK activity and suggest an important role of Src in this process. Finally, the targeting of CD24 by antibodies could represent a novel route for tumor therapy.