The involvement of porphyrogenic steroids in the development of experimental porphyria

Summary Hexachlorobenzene alters the hepatic steroid metabolism, and it was suggested that a porphyria was induced by overproduction of 5-H-steroids. Structurally similar chlorinated hydrocarbons (pentachlorobenzene, pentachlorophenol, 2,4,5-trichlorophenol) without porphyrogenic activity did not affect the steroid metabolism in rat liver.Dedicated to Prof. Dr. L. Róka on the occasion of his 60th birthday.     

Wirkung von 6β-Methoxy-9β,10α-pregna-4,6-dien-3,20-dion

Summary 6-Methoxy-9,10 -pregna-4,6-diene-3,20-dione inhibites the ⁴-3-oxosteroid-5-reduction in microsomes and the ⁴-3-oxosteroid-5-reduction in the soluble fraction of male rat liver. The 3- and 3-hydroxysteroid dehydrogenase are not inhibited by this substance.

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Diese Arbeit wurde von der Firma Hoffmann-La Roche, Basel, unterstützt.     

Participatory Impact Assessment of Food Securing Upgrading Strategies in Rural Tanzania

Systemic Practice and Action Research - Subsistence farmers in sub-Saharan Africa aim for strategies to enhance their food security. Implementing upgrading strategies (UPS) must be assessed prior...     

Multi-Disciplinary North-South Collaboration in Participatory Action Research on Food Value Chains: a German-Tanzanian Case Study on Perceptions,Experiences and Challenges

Systemic Practice and Action Research - Upgrading local food value chains is a promising approach to invigorating African food systems. This endeavour warrants multi-disciplinary North-South...