新型纱线定长(测长)器的研制

络筒机在络纱时容易造成纱线长度长短不一，这将导致后续整经工序中纱线的巨大浪费。笔者研制出一种新型纱线测长器，在纱线卷绕的过程中对其进行精确测量，达到减小误差、节约成本的目的。     

蚕丝蛋白仿生多肽RAGA16的纳米结构与性能研究

利用天然蛋白质氨基酸序列设计生物仿生材料是近年来兴起的一个热门研究领域.本文中将蚕丝蛋白特征氨基酸序列(Gly-Ala-Gly-Ala-Gly-Ser)部分引入离子互补型多肽RA-DA16-Ⅰ中,设计了新型多肽RAGA16.采用原子力显微镜(AFM)、旋转流变仪(Rheometer)、傅立叶变换红外光谱仪(FTIR)、倒置荧光显微镜等技术对多肽RAGA16的自组装结构、肽链的二级结构、流变学性能以及细胞相容性等进行研究.结果表明,蚕丝蛋白多肽序列引入后,多肽RAGA16具有自组装特性,能够自组装形成致密的纳米级三维网络结构,所形成的水凝胶力学性能明显提高,通过分析得知这可能是由于多肽二级结构中Silk Ⅰ结构成分比例增加所致.荧光染色显示,绝大多数接种于多肽水凝胶中的小鼠前成骨细胞MC3T3-E1能存活,且在不同的三维平面上生长增殖.综上,利用蚕丝蛋白特征序列对RADA16-Ⅰ进行仿生改性后,对拓展多肽材料在生物医学领域的应用具有重要意义.     

崇启大桥钢箱梁试验段制造工艺技术研究

本文基于崇启大桥主桥钢箱梁梁段制造工艺参数采集的需要,对试验段的制造工艺技术进行了探讨与研究。     

房山五渡桥钢塔架施工关键技术

房山五渡桥采用三角钢架悬吊连续梁组合桥结构体系,主塔采用十字形钢箱截面,钢塔架截面变高变宽均采用线性变化,总高为35m,与V墩共同组成W型,钢塔架共分11段进行吊装。由于倾斜型钢塔架施工难度大,质量和精度要求较高,因此针对钢塔架预制、防腐、搭设临时支架、吊装等方面进行了深入的研究,提出钢塔架的施工全过程的重点和难点方面的施工关键技术。     

基于梁格法的异型箱梁有限元计算分析

采用梁格法对一个结构较为复杂的异型箱梁建立空间有限元模型进行了分析计算,通过计算分析研究表明:用梁格法来分析桥梁上部结构,能得到比较准确的计算结果,在工程设计中是一种比较简便、高效、实用的计算方法。     

利用图像处理技术测定丝/毛混纺比的方法初探——特征参数的选择及模式识别

主要介绍了图像处理技术测定丝/毛混纺比时多种特征参数的选择及识别敏感度的分析,并利用多元分析方法对目标信号进行了识别和分类。     

斜度对多梁式连续斜交小箱梁桥力学性能的影响

基于斜交箱梁桥弯扭耦合的受力特点,利用梁格法求解了自重作用下0°,10°,20°,30°,45°,60°共6种情况下多梁式连续小箱梁的弯矩、扭矩、应力和位移,对比分析了斜度对斜交连续小箱梁桥力学性能的影响。研究结果表明,在常用斜度范围(θ60°)内,主梁跨中截面的弯矩、位移随斜度的增大先减小后增大,而墩顶截面的弯矩、跨中截面的扭矩随斜度的增大先增大再减小;各截面上缘应力随斜度的增大先增大后减小,而下缘应力则随斜度的增大先减小后增大;当斜度达到临界斜度45°时,各截面的内力、位移均达到最值,此时,跨中截面扭矩值与正桥跨中截面的扭矩值相差倍数达到了100以上;斜度为0°~10°时,主梁弯矩、应力和位移变化均较小,可近似按直桥计算。在设计中,应充分考虑斜度对斜交箱梁弯扭耦合性能的影响,合理布置墩顶截面和跨中截面的抗弯、抗扭预应力钢束,使设计更经济、安全。     

Conformational Transitions and Self-assembly of Regenerated Spider Silk Protein in Water

Spider silk, relying on its exceptional mechanical properties, has attracted extensive attention throughout the world. The structure of a material can influence its mechanical properties. Investigation of the structure of spider silk includes amino acid composition, molecular structure, self-assembly, and crystallization, among other characteristics. Herein, the effects of concentration, time, alkali metal ions （Na^＋and K ^＋ ） and pH on the conformational transition and self-assembly of regenerated Ornithoctonus huwena spider dragline silk protein （spidroin） in water were investigated using circular dichroism （CD） and atomic force microScopy （AFM）. Spidroin concentration, time and Na ＋ ions slightly influenced the conformational transition of spidroin molecules. However, K ＋ ions and pH induced the formation of a β- sheet structure. Increasing spidroin concentration or time increased the aggregation of spidroin and enhanced the formation of nanoffiaments. K ~ ions enhanced the serf-assembly of spidroin into nanofilaments. The self-assembled nanofilaments appeared at a pH of approximately 6. 11. Both lower and higher pH induced aggregation. At a lower pH, the aggregation was composed of nanopartides, whereas higher pH induced the aggregation of nanoffiaments, likely from the synergistic effect of Na ^＋ ions and pH.     

Silk Fibroin Microspheres： Preparation and Application for Controlled Drug Delivery

Silk fibroin （SF）, a natural protein polymer, has several unique properties such as aqueous processability, biocompatibility, and biodegradability. Due to these advantageous properties, it is promising for applications in various fields, especially drug delivery. In this paper, the simple preparation of SF microspheres was discussed via self-assembly. Some of SF＇s physicochemical properties and morphology were also investigated. The results show that the morphology, size and size distribution of silk microspheres depend upon various processing parameters, especially including volume ratios among SF, ethanol and polyvinyl alcohol （PVA）. Regular silk microspheres were obtained in PVA solution when adjusting the volume ratios of silk to ethanol from 20：1 to 20： 9. We also found that SF microspheres with various appearances were formed by addition of different PVA solution concentrations under a constant silk solution to ethanol volume ratio. From the Fourier transform infrared spectroscopy（FTIR） of silk microspheres, it was found that introducing ethanol into the SF solution induced conformational change from random coil to β-sheet. Additionally, under the observation of scanning electron microscopy （ SEM）, the shape of self-assembled silk microspheres was determined to be spherical. Finally, SF＇s potential as drug delivery carriers was discussed in the experimental results.