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排序方式: 共有229条查询结果,搜索用时 531 毫秒
1.
绿脓杆菌外毒素A与Ⅱ型单纯疱疹病毒糖蛋白嵌合表达质粒的构建及其免疫原性的研究 总被引:1,自引:1,他引:1
构建外毒素结构域Ⅰ a基因(EPA103)与Ⅱ型单纯疱疹病毒糖蛋白(HSV-2-gD)嵌合蛋白表达载体(pET-EgD),得到嵌合表达蛋白.利用外毒素结构域Ⅰ a基因表达蛋白的佐剂效应,以pET-EgD表达嵌合蛋白免疫Balb/c小鼠.结果显示:嵌合表达蛋白(pET-EgD)免疫小鼠,可在小鼠体内诱导产生抗HSV-2特异性抗体.嵌合表达蛋白(pET-EgD)具有较强的免疫原性,为开发研究Ⅱ型单纯疱疹核酸疫苗奠定了基础. 相似文献
2.
介绍了应用于多媒质区域电磁问题的介质子网格时域有限差分法.该方法在保证精度的前提下,节省了大量计算时间及计算机内存,尤其在处理多媒质界面方面具有很大的优势. 相似文献
3.
LIUZhifei TUOShouting ZHAOQuanhong CHENGXinrong HUANGWei 《科学通报(英文版)》2004,49(20):2190-2197
The most prominent cooling event of the Earth surface during Cenozoic in the long-term transition from a non-glaciated planet, or “green-house world”, to a polar, glaciated planet, or “ice-house world”, is the Earliest Oligocene Glacial Maximum (EOGM) above the Eocene/Oligocene boundary at about 33.7 Ma. Planktonic and benthic foraminiferal oxygen and carbon isotopes, carbonate content, and coarse fraction, along with high-resolution color reflectance and magnetic susceptibility records during 35-30 Ma, from deep-water Sites 1262 and 1265, Ocean Drilling Program (ODP) Leg 208 in South Atlantic, reveal the global cooling event occurring in both surface and deep oceans. The results show that the earliest Oligocene δ^18O values during 33.5-33.1 Ma represent the magnitude of continental ice sheets on east Antarctica and indicate the large decrease in both surface and deep water temperatures of worldwideoceans. The δ^13C records show the large excursion during the period of EOGM event and indicate some types of shift in global carbon reservoir, probably demonstrating the sudden increase in organic carbon burial rates and the changes in the distribution and timing of production. At the same time, lithologic composition, carbonate content, color reflectance, and coarse fraction brought about significant changes close to the Eocene/Oligocene boundary, reflecting the abrupt deepening in the carbonate compensation depth (CCD). Changes in carbonate content were revealed from the color reflectance identify periodicities associated with eccentricity of the Earth‘s orbit (100 and 400 ka), further indicating orbitally forced global climate variations in the Early Oligocene. 相似文献
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5.
《Journal of Natural History》2012,46(11):1597-1615
Over 8000 amphipods were examined from coastal (primarily intertidal) and anchialine pool habitats of Ascension Is. Twenty-seven species, of which 14 are undescribed, were identified. Comparison of species from Ascension with amphipods found in possible source areas suggests that most colonization of the island by these animals has been via the Benguela Current. Possible western Atlantic faunal contributions are significantly lower than for other marine taxa that have been studied at Ascension, all of which are generally characterized by having dispersive larval stages. The high proportion of apparently endemic species, which exceeds that described for amphipods of other oceanic islands, is probably due to both the island's isolation and incomplete faunal surveys in possible source areas. Amphipod species diversity is low, a probable consequence of the size, isolation, youth and low habitat variability of Ascension Is. Consistent with other Atlantic islands that have been studied, nestlers predominate (56% of the species), with tubicolous species (33%) of secondary importance and inquilines (11%) making only a minor contribution. Three species occur in the anchialine pool habitat. Rather unexpectedly, caprellid amphipods are absent. 相似文献
6.
Wilson J. E. M. Costa Axel M. Katz José Leonardo O. Mattos Pedro F. Amorim Beatrizz O. Mesquita Paulo J. Vilardo 《Journal of Natural History》2019,53(47-48):2905-2928
ABSTRACT This study is primarily directed to the most poorly known species of the genus Trichomycterus, comprising five nominal species (T. florensis, T. immaculatus, T. nigricans, T. paquequerensis and T. santaeritae) endemic to south-eastern Brazil. One of them, T. nigricans, is the type species of the genus, involved in taxonomic problems for over 150 years. A detailed historical review, accompanied by examination of type specimens and recent collections, revealed that the correct type locality of T. nigricans is in the vicinity of Rio de Janeiro, not Santa Catarina as commonly appears in the literature; specimens previously misidentified as T. nigricans from Santa Catarina belong to a possibly undescribed species of the genus Cambeva; T. paquequerensis is a synonym of T. immaculatus, and T. florensis is a synonym of T. santaeritae; and the hypothesis that T. santaeritae is closely related to the Amazon Sarcoglanidinae is refuted. The three valid species are redescribed. These species are members of a clade also including T. caipora that is highly supported by molecular data, diagnosed by a pronounced posterior maxillary process and caudal fin emarginate at least in larger specimens. A subclade comprising T. caipora, T. nigricans and T. santaeritae is diagnosed by a long maxilla and a bifid anterior extremity of hypobranchial 3. 相似文献
7.
为解决南大西洋至几内亚湾海域的海浪组成成分、传播特性及来源这3个该海域一直需要解决的问题,建立SWAN (Simulating WAves Nearshore)双层嵌套海浪模型对南大西洋至几内亚湾冬季海浪时空分布进行模拟分析,结果表明:南大西洋海浪有效波高呈高纬度区(30°S以南)向低纬度区(30°S以北)递减的趋势 ,高纬度区海浪传播方向与风场关系密切,低纬度区则与风场差异明显;南大西洋涌浪波高与混合浪波高分布高度相关,涌浪在混合浪中所占比例较大,尤其在风速较小的低纬度海域更为显著;南大西洋中部至几内亚湾存在相对固定的S-SW涌浪系统,其能量在二维海浪谱上分布集中,空间方向上分布范围较窄;模拟时段内几内亚湾呈明显的涌浪主导状态,通过对有效波高最大时刻的一次涌浪过程溯源发现,影响几内亚湾的涌浪可追溯至约6.5天前南大西洋咆哮西风带海域的强风浪。 相似文献
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9.
Ivanklin Soares Campos-Filho Jonathas Teixeira Lisboa Giovanna Monticelli Cardoso 《Journal of Natural History》2018,52(7-8):457-482
To date, the family Pudeoniscidae includes six species and three genera, Pudeoniscus, Brasiloniscus and Iansaoniscus, with distributions restricted to Brazil. Here, we redefine the family Pudeoniscidae based on the discovery of a new genus and two new species, Oxossioniscus pataxo sp. nov. and Oxossioniscus akoko sp. nov., from the Brazilian Atlantic forest in the state of Bahia, and on the examination of Pudeoniscus birabeni and Pudeoniscus obscurus. Moreover, P. obscurus is re-described and new records are provided for P. birabeni.
http://www.zoobank.org/urn:lsid:zoobank.org:pub:A0123730-C623-49CE-8665-AE17FDDF994A. 相似文献
10.
《Journal of Natural History》2012,46(30):2759-2794
New data on the warm temperate and tropical east Atlantic Bathyporeia species are presented. Four new species are described: Bathyporeia cunctator sp. nov. from South Africa, B. chevreuxi sp. nov. from Senegal, B. gladiura sp. nov. from South Africa, and B. griffithsi sp. nov. from Namibia. Bathyporeia cunctator sp. nov. and B. chevreuxi sp. nov. are very closely related to the west European B. tenuipes Meinert, 1877 and the Mediterranean B. lindstromi Stebbing, 1906; these four cryptic species forming the complex tenuipes. Bathyporeia griffithsi sp. nov. and B. gladiura sp. nov. are highly distinctive new species. The morphotype “sunnivae” of Bathyporeia guilliamsoniana is recorded for the first time outside the Mediterranean Sea, in the Canary Islands. An identification key to all known Bathyporeia species is given. 相似文献