Vaults and the major vault protein: Novel roles in signal pathway regulation and immunity

The unique and evolutionary highly conserved major vault protein (MVP) is the main component of ubiquitous, large cellular ribonucleoparticles termed vaults. The 100 kDa MVP represents more than 70% of the vault mass which contains two additional proteins, the vault poly (ADP-ribose) polymerase (vPARP) and the telomerase-associated protein 1 (TEP1), as well as several short untranslated RNAs (vRNA). Vaults are almost ubiquitously expressed and, besides chemotherapy resistance, have been implicated in the regulation of several cellular processes including transport mechanisms, signal transmissions and immune responses. Despite a growing amount of data from diverse species and systems, the definition of precise vault functions is still highly complex and challenging. Here we review the current knowledge on MVP and vaults with focus on regulatory functions in intracellular signal transduction and immune defence. Received 27 June 2008; received after revision 25 July 2008; accepted 30 July 2008     

Research on secure buyer-seller watermarking protocol

A new buyer-seller watermarking protocol is proposed by applying a double encryption method and a novel mechanism of embedding a buyer＇s watermark. The protocol can effectively prevent against collusion attacks and the man in the middle attack if the third party is not trusted. Also, based on the proposed scheme for the first-hand transaction, a new buyer-reseller watermarking protocol and a formal multi-party watermarking protocol are also proposed. The proposed buyer-resell watermarking protocol only needs the original seller to provide transfer certificate and encryption-decryption service to support the second-hand transaction, and the multi-party watermarking protocol with distributed certificate authorities can overcome the difficulty in the combination of multicast mechanism with multiple unique watermarks and allow a seller to multicast the watermarked digital contents and key transaction information to n buyers. Furthermore, the idea of zero knowledge proof is also applied into the proposed scheme to allow the seller to take an effective control on the task performed by the third party.     

COHERENT, REGULAR AND SIMPLE SYSTEMS IN ZERO DECOMPOSITIONS OF PARTIAL DIFFERENTIAL SYSTEMS

1.IntroductionWeareconcernedwithalgebraicdifferentialpolynomials(abbreviatedas'd-pcis)inafinitenumberofdifferentialindeterminatesoveradifferentialfieldofcharacteristic0.Givenafinitesetofsuchd-pcis,wewouldliketostudyd-Zero(),thedifferentialalgebraicsetdefinedbyPoverauniversaldifferentialfield.Wemayaskwhetherd-Zero()isempty,whetherad-pcivanishesond-Zero()(differentialradicalidealmembershipproblem),whatthedimensionofd-Zero()is,howtodecomposed-Zero()intoirreduciblealgebraicdifferentialsets,andso…     

Vaidya-Bonner空时中Dirac粒子和标量粒子的能级比较

用旋量零标架方法推导出Vaidya-Bonnet空时中Dirac粒子的能级方程;从Hamilton-Jacobin方程出发,通过广义Tortoise变换推导出该时空中标量粒子的能级方程;发现Dirac粒子和标量粒子在该空时中的能量分布在视界附近有着明显的不同,但在远离视界处即r→∞时是相同的,都等于它的静止质量,两类粒子的能级方程则有明显区别。     

高光谱遥感技术在悬沙水体研究中的应用

水体中悬浮泥沙影响到水体的透明度和水色等光学性质，还密切关系到河口海岸冲淤变化过程。采用高光谱遥感技术获得悬沙水体的反射光谱数据，同时从原理上来计算反射率。针对传统水体遥感测量的局限性，地物光谱仪测量方式更加合理。选用地物光谱仪和光纤光谱仪进行研究，得到以下结论：随着悬沙浓度的增高，反射率也增高，且发生反射的波段范围有所增大；离水面一定距离时测得的悬沙反射率的误差主要来自于天空光，近水面虽然减少了天空光的部分影响，但光纤光谱仪较敏感，受水面波动的影响较大；到水面下光强变弱，利用光纤光谱仪可以不受天空光影响直接获得水体反射率。     

基于数值模拟的无芯模旋压收口工艺

为深入研究旋压收口成形机理,并为实际工艺过程提供依据,文中建立了单旋轮无芯模旋压收口成形的大变形弹塑性有限元模型,使用有限元分析软件MARC,对旋压收口成形过程进行三维弹塑性有限元模拟．对旋压成形过程的变形机理及应力应变分布的分析结果表明,变形金属在旋轮与毛坯的接触区受三向压应力作用;从已变形区到未变形区,轴向拉应变逐渐过渡为压应变,径向压应变则过渡为拉应变．随着压下量的增加,等效应力增加,径向应力最大值均出现在口部直身以及过渡圆角内壁,最薄区域（拉裂危险截面）出现在过渡圆角位置．有限元模拟结果与实际旋压变形规律吻合良好,为收口旋压成形工艺的制定提供了理论依据．     

含纳米硅粒SiO2薄膜的光致发光

采用RF磁控溅射技术制备含纳米硅的SiO2薄膜.通过对Si-SiO2复合靶的比分进行调节控制,并在不同的温度下进行高温退火得到不同粒径的纳米硅.利用XRD对样品进行分析得出纳米硅的平均粒径;对样品测量光致发光谱,其发光峰分别位于361 nm和430 nm,比较发现光致发光的峰位随比分的改变有微小的蓝移.文中对发光机理进行初步讨论.     

银/聚吡咯/二氧化钛复合纳米粒的制备与结构表征

以钛酸四丁酯、硝酸银和吡咯为原料采用溶胶-凝胶法制备了银/聚吡咯/二氧化钛(Ag/PPy/TiO2)复合纳米粒,考察了PPy单体用量、原料配比等因素对制备复合纳米粒的影响。运用扫描电镜(SEM)、透射电镜(TEM)、红外光谱仪(FTIR)等测试方法对复合纳米粒进行了表征。结果表明,Ag/PPy/TiO2复合纳米粒具有棒状的核壳结构,聚吡咯包覆在Ag和TiO2纳米粒子的表面。     

汽车轮辐错距强力旋压成形的有限元仿真

摘要： 利用ABAQUS软件建立轮辐三旋轮的错距强力旋压过程的弹塑性有限元仿真模型,并对成形过程进行分析;给出了仿真模型边界条件的施加方法和旋轮旋压轨迹曲线的加载方法;通过计算动能及伪应变能与内能的比率,并采用逆向扫描技术和实验测量方法对比分析仿真结果与轮辐生产件,以验证所建立模型的正确性.结果表明：与尾顶接触的材料不发生塑性变形,其他部位材料沿轮辐周向的塑性变形程度相当,而沿母线方向的塑性变形程度不同,并形成了等效塑性应变环和厚度环;在成形轮辐弯曲圆角处和外缘收口区域,材料的塑性变形程度较大,且材料堆积缺陷易出现在成形轮辐外缘收口区域;沿母线方向上不同位置处的轮辐的壁厚不同,壁厚变化遵循正弦规律.     

疏松砂岩油藏封隔颗粒防砂控水技术矿场实践

南海东部的F油田为疏松砂岩稠油油田,针对投产后出现的储层出砂堵塞筛管,油井产量递减快、见水后含水上升快等难题,在充分调研常规防砂控水技术优缺点的基础上,提出了一种由亲油疏水材料构成的封隔颗粒防砂控水技术。利用实验、油藏工程、数值模拟等方法评价了封隔颗粒的防砂控水效果。结果表明：封隔颗粒防砂控水技术具有无需找水、全井段控水、防砂、绿色环保等多种优势,配合自适应流量控水阀(autonomous inflow control device, AICD),防砂控水效果进一步提升;F油田部分单井矿场采用封隔颗粒防砂控水后,有明显的无水采油期,在相同采出程度的情况条件下,含水上升率明显更低,防砂控水增油效果显著。该技术为类似疏松砂岩油田的防砂控水开发提供了借鉴,推广前景良好。