In vitro mutagenicity testing of a potent,new, benzoyl urea insect growth regulator

Summary Bacterial mutagenicity assay to detect potential chronic toxicity of a potent, new, benzoyl urea insect growth regulator (CGA-112913 or IKI-7899, formerly UC-62644) was conducted using 5 histidine auxotrophs ofSalmonella typhimurium. Tests within the concentration range of 0.9–500 g (saturating)/plate of the compound with and without the 5–9 mammalian metabolic activation system showed no mutagenic effects clearing the way for long-term chronic toxicology studies.The authors thank Professor Bruce N. Ames for supplying the tester strains together with all the relevant information for conducting the bioassays and Ms. Norma Charlebois for her meticulous technical assistance.     

具有优先级的深度确定性策略梯度算法在自动驾驶中的应用

深度确定性策略梯度(deep deterministic policy gradient,DDPG)算法在自动驾驶领域中应用广泛,但DDPG算法因采用均匀采样而导致低效率策略比例较高、训练效率低、收敛速度慢等.提出了基于优先级的深度确定性策略梯度(priority-based DDPD,P-DDPG)算法,通过优先级采样代替均匀采样来提升采样利用率、改善探索策略和提高神经网络训练效率,并且提出新的奖励函数作为评价标准.最后,在开源赛车模拟(The Open Racing Car Simulator,TORCS)平台上对P-DDPG算法的性能进行了测试,结果表明相对于DDPG算法,P-DDPG算法的累积奖励在25回合之后就有明显提升而DDPG在100回合之后训练效果才逐渐显现,提升约4倍.P-DDPG算法不仅训练效率提升且收敛速度加快.     

用复性电泳技术研究溶酶体蛋白水解酶的性质和活性

介绍了复性单向电泳（Ｇ－ＰＡＧＥ）和复性双向电泳（ＩＥＦ－Ｇ－ＰＡＧＥ）的概念、原理、方法、应用范围、优缺点和使用该方法应注意的事项。并用该方法定性和定量分析了Ｃ６大白鼠神经胶质瘤细胞酸性溶酶体蛋白水解酶的性质和活性。     

神经网络中误差反传算法的分析与改进

分析了ＢＰ网络存在的主要问题及其产生原因,提出了改进算法ＢＰＧ,以共轭梯度方向代替梯度方向进行搜索,并在学习过程中采用不精确的一维搜索、限幅和条件轮回等措施．计算机仿真结果表明：改进的ＢＰＧ算法优于原ＢＰ算法．     

SAG法合成钛酸铅纳米晶粒的工艺和结构研究

ＳＡＧ法合成钛酸铅纳米晶粒的工艺和结构研究李永祥刘泽吴冲若（东南大学电子工程系,南京２１００９６）ＰｂＴｉＯ３是应用广泛的铁电和光电材料之－,研究ＰｂＴｉＯ３纳米晶粒的合成技术和电学性能对基础研究和新型复合功能材料研究都有重要意义．作者曾采用Ｓｏｌ...     

An all solid-state electrochromic smart window

An all solid-state electrochromic smart window employing prussian blue and electrodeposited WO₃ film with poly (vinyl chloride) (PVC) gel electrolyte that has high conductivity (2 mS/cm) at room temperature has been fabricated for the first time. The smart window has beell found to be excellent for electrochromism and memory characteristics.     

Harmonic maps with potential from complete manifolds

Harmonic maps with potential from complete manifolds are considered. This is a new kind of maps more general than the usual harmonic maps relating to many interesting problems such as equilibrium system of ferromagnetic spin chain and Neumann motion. Aiming at the general properties, the author derives basic gradient estimates and then Liouville type results for these maps, which are interesting in constrast to those of the usual harmonic maps for the presence of potentials.     

有限稀释法筛选重组AcNPV病毒

有限稀释法筛选重组ＡｃＮＰＶ病毒钟劲胡美浩１）（北京大学生命科学学院,北京,１００８７１）关键词重组病毒;梯度稀释;筛选;测活中图分类号Ｑ３３２０引言昆虫杆状病毒表达系统是一高效表达外源基因的表达系统。用于基因工程表达外源基因的ＡｃＮＰＶ（ａｕｔｏｇ...     

毛细管电泳中溶质系统的熵平衡方程

采用非平衡热力学的研究方法,提出了溶质系统在毛细管电泳（ＣＥ）分离过程中的熵平衡方程．指出了各种非平衡因素不仅使溶质带展宽,同时也促使溶质带间分离．阐明了溶质系统的熵平衡方程是整体优化ＣＥ分离大系统的基础．     

用胶束毛细管电泳法测定清开灵注射液中的有效成分

采用胶束毛细管电泳法（ＭＥＣＣ）对清开灵注射液中有效成分黄芩甙（Ｂａｉｃａｌｉｎ）、绿原酸（Ｃｈｌｏｒｏｇｅｎｉｃａｃｉｄ）、去氧胆酸（Ｄｅｏｘｙｃｈｏｌｉｃａｃｉｄ）、胆酸（Ｃｈｏｌｉｃａｃｉｄ）及Ｌ－苯丙氨酸（Ｌ－ｐｈｅｎｙｌａｌａｎｉｎｅ）进行定量检测,其含量分别为１３．５、２．５８、０．７６０、０．９８０、０．０００ｇ／Ｌ,得到了满意的分离效果。