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11.
12.
对膜结构裁剪分析中目前应用较广的裁剪线的生成方法进行了比较研究,提出修正二次测地线法。确定了采用测地线作为裁剪线及展开图形的基准线。之后对已有图形展开方法——二次测地线法做了适当改进,提出修正二次测地线法。 相似文献
13.
M. T. Santini R. Masella A. Cantafora S. W. Peterson 《Cellular and molecular life sciences : CMLS》1992,48(1):36-39
We have recently demonstrated, using electron paramagnetic resonance (EPR) spectroscopy, that insulin receptor internalization in response to insulin incubation (down-regulation) in human erythrocytes is accompanied by a transient decrease in membrane order, as measured by the 2T order parameter. Since membrane lipids play such an important role in receptor internalization, we investigated the possible effects that an alteration of the normally-occurring lipid profile might have on down-regulation and the concomitant transient decrease in membrane order. Consequently, human erythrocytes enriched with cholesterol and erythrocytes from cirrhotic patients were examined, because both of these groups of cells have a higher cholesterol/phospholipid molar ratio (CH/PL) than controls. The 5-nitroxystearate spin label, which inserts into the lipid bilayer of cell membranes, was used to monitor changes in 2T for a 3-h period at 37°C. We report here that both cholesterol-enriched and cirrhotic erythrocytes do not down-regulate, as demonstrated by binding assays, and that they do not show the typical transient decrease in membrane order observed in controls. The results seem to indicate that a more ordered membrane inhibits internalization of the insulin receptor in erythrocytes, and that an increase in membrane disorder is necessary for insulin receptor down-regulation. 相似文献
14.
A. Ballio 《Cellular and molecular life sciences : CMLS》1991,47(8):783-790
During the last decade increasing attention has been directed towards the biochemical mechanisms responsible for the biological activity of phytotoxins. Studies on the mode of action of some non-host-selective phytotoxins, some following on from previous observations, have demonstrated a very specific interaction with particular components of the cell machinery, and have suggested the possible use of these phytotoxins as tools for the investigation of important biochemical processes. This review article reports and discusses results of studies carried out in the 1980s with seven non-host-selective fungal toxins: brefeldin A, cercosporin,Cercospora beticola toxin, fusicoccin, ophiobolins, tentoxin, and zinniol. Each of these interferes with the life of the host by interacting with a different biochemical target. 相似文献
15.
Summary We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins. Porin, like all outer mitochondrial membrane proteins studied so far is made as a precursor without a cleavble signal sequence; thus targeting information must reside in the mature sequence. At least part of this information appears to be located at the amino-terminal end of the molecule. Transport into mitochondria can occur post-translationally. In a first step, the porin precursor is specifically recognized on the mitochondrial surface by a protease sensitive receptor. In a second step, porin precursor inserts partially into the outer membrane. This step is mediated by a component of the import machinery common to the import pathways of precursor proteins destined for other mitochondrial subcompartments. Finally, porin is assembled to produce the functional oligomeric form of an integral membrane protein wich is characterized by its extreme protease resistance. 相似文献
16.
多方向线性特征提取的模板构造及处理方法 总被引:2,自引:0,他引:2
黄毅 《合肥工业大学学报(自然科学版)》1998,(2)
常用的空域定向滤波模板方法具有较好的方向针对性,但是对于某些研究方向,如提取遥感图象线性特征等,常用的定向滤波模板不太适合,原因是它所提供的多个方向中,有重复多余的方向,因而模板方向就少得不足以全面反映被处理遥感图象的特点,不利于图象中线性特征的提取及模式识别。文章在常用的空域定向滤波模板基础上,对构造新的多方向和多尺寸的滤波模板,进行了有效的研究及详细的阐述。 相似文献
17.
The relaxation of the highly vibrationally excited CO (v = 1–8) by CO2 is studied by timeresolved Fourier transform infrared emission spectroscopy (TR FTIR). 193 nm laser photolysis of the mixture
of CHBr3 with O2 generates the highly vibrationally excited CO(v) molecules. TR FTIR records the intense infrared emission of CO(v→v-1). The
vibrational populations of each level of CO(v) have been determined by the method of spectral simulation. Based on the evolution
of the time resolved populations and the differential method, 8 energy transfer rate constants of CO(v = 1–8) to CO2 molecules areobtained: (5.7±0.1), (5.9±0.1), (5.2±0.2), (3.4±0.2), (2.4±0.3), (2.2±0.4), (2.0±0.4) and (1.8±0.6) (1014 cm3 · molecule−1 · s−1), respectively. A two-channel energy transfer model can explain the feature of the quenching of CO(v) by CO2. For the lower vibrational states of CO, the vibrational energy transfers preferentially to the u3 mode of CO2 For the higher levels, the major quenching channel changes to the vibrational energy exchange between CO(v→v-1) and the u1 mode of CO2. 相似文献
18.
The vibrational energy transfer from highly vibrationally excited CO to H2O molecules is studied by time-resolved Fourier transform infrared emission spectroscopy (TR FTIR). Following the 193 nm laser
photolysis of CHBr3 and O2 the secondary reactions generate CO(v). The infrared emission of CO(v → v−1) is detected by TR FTIR. The excitation of H2O molecules is not observed. By the method of the spectral simulation and the differential technique, 8 rate constants for
CO(v)/H2O system are obtained: (1.7 ±0.1), (3.4 ±0.2), (6.2 ±0.4), (8.0 ±1.0), (9.0 ±2.0), (12 ±3), (16 ±4) and (18 ±7) (1013cm3 · molecule-1· s-1). At least two reasons lead to the efficient energy transfer. One is the contributions of the rotational energy to the vibational
energy defect and the other is the result of the complex collision. With the SSH andab initio calculations, the quenching mechanism of CO(v) by H2O is suggested. 相似文献
19.
介绍了采用模板和继承方法设计可重用C++类的方法,探讨了采用继承和模板的区别.介绍了重用C++类时的方法和应注意的问题. 相似文献
20.
应用表面反应红外动态技术考察了促进型铑催化剂Rh-Ag/SiO2上CO吸附及其加氢反应的性能,结果表明:线式吸附态的CO对氢的反应性能高于桥式吸附的CO,是加氢反应的主要活性吸附态.反应条件下温度升高有利于Rh-Ag/SiO2上线/桥CO吸附态强度比值的增加.表面反应生成了表面甲酰基、甲酸盐、乙酰基、乙酸盐、乙烯酮及烯醇盐等关键的C1-2含氧中间体.助剂Ag的加入提高了铑催化剂上CO吸附态的线/桥强度比值以及线式吸附CO的加氢反应速率和C2含氧物的生成率. 相似文献