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131.
指出在目前完善城市低保体制的工作中首先应该加强对低保工作的思想认识,其次应该加强政府的调控职能,缩小地区间贫富差距.还提出了一个“大低保”概念及其建制策略,解释了不确定性现象,并提出了相应对策,最后还就几个具体问题给出了对策. 相似文献
132.
WANGYutang WENYunyi MANing SHILei 《科学通报(英文版)》2003,48(24):2710-2714
The cardiac protective role of a novel erythro-cyte-derived depressing factor (EDDF) on spontaneous hy-pertensive rats (SHR), calcium overload (CaO) rats and Wistar rats and its mechanism was evaluated. Mean artery pressure (MAP), heart rate (HR) and LVdp/dtmax were measured by physiological recorder. The effect of EDDF on the Ca2+-ATPase activity in myocardial sarcoplasmic reticu-lum (SR) of CaO rats was determined by inorganic phos-phate assay. Calcium transport in myocytes was measured by 45Ca2+ radioactive isotope measurement. The phosphoryla-tion levels of extracellular signal-regulated protein kinases (ERK1/2) in myocardial tissue of SHR and CaO rats were measured by Western blot method. And the ultrastructures of cardiac muscle cells were observed with the transmission electron microscope. The results indicated that EDDF could significantly decrease MAP, HR and LVdp/dtmax in a dose dependent manner (P < 0.05). It seems that the mechanism might relate with activating the Ca2+-APTase, enhancing the uptake and release of Ca2+ from SR (P < 0.05), decreasing the phosphorylation levels of ERK1/2 of myocytes (P < 0.01) and lightening the ultrastructural lesion of cardiac muscle cells. In CaO rats, the Ca2+-ATPase activity decreased clearly com-pared to control (64.99 7.16 vs 94.48 7.68 nmol·min-1 ·mg-1 protein, P < 0.01), while EDDF (100 mg/mL) could significantly increase the activity (87.93 ?9.54 vs 64.99 ?7.16, P < 0.05, n = 7). Both uptake and release rate of Ca2+ (祄ol 45Ca2+/g protein/min) from myocardial SR of CaO rats re-markably decreased compared to control (32.40 ?2.70 and 15.46 ?1.49 vs 61.09 ?10.89 and 25.47 ?4.29, P < 0.05); EDDF (100 mg/mL) could significantly stimulate their activi-ties (50.48 6.76 and 21.76 2.75 vs 32.40 2.70 and 15.46 1.49, P < 0.05). EDDF could evidently down-regulate the phosphorylation of ERK1/2 in myocardial tissue from SHR and CaO rats (P < 0.01), lighten the ultrastructural lesion of cardiac muscle cells of SHR as well. It is concluded that EDDF seems to play protective roles on both structure and function of heart, which closely related with amelioration of Ca2+ transport and inhibition of Ca2+-MAP kinase pathway. 相似文献
133.
Scarborough GA 《Cellular and molecular life sciences : CMLS》2000,57(6):871-883
Living cells require membranes and membrane transporters for the maintenance of life. After decades of biochemical scrutiny, the structures and molecular mechanisms by which membrane transporters catalyze transmembrane solute movements are beginning to be understood. The plasma membrane proton-translocating adenosine triphosphatase (ATPase) is an archetype of the P-type ATPase family of membrane transporters, which are important in a wide variety of cellular processes. The H+-ATPase has been crystallized and its structure determined to a resolution of 8 angstrom in the membrane plane. When considered together with the large body of biochemical information that has been accumulated for this transporter, and for enzymes in general, this new structural information is providing tantalizing insights regarding the molecular mechanism of active ion transport catalyzed by this enzyme. 相似文献
134.
Zheng Xiaojing 《中国科学基金(英文版)》2007,15(1):29-33
It is very necessary for the investigation on mechanism of windblown sand movement to understand and find out effective measures of preventing and reducing danger of windblown sands,which also deals with some general characters and hot spots in the scient 相似文献
135.
136.
分别构造了具有小世界和无标度拓扑结构的束流输运网络,为了实现网络多目标同步控制的目的,把束流输运网络按照需要分成多局域网络,采用多局域网络的全局耦合分局域控制方法,实现了分区局域网络中各自所需的多目标(不动点和周期态等)的稳定控制.该方法可以拓广应用于其他复杂网络的多目标控制. 相似文献
137.
Concentration level and distribution of polycyclic aromatic hydrocarbons in soil and grass around Mt. Qomolangma, China 总被引:2,自引:0,他引:2
WANG XiaoPing YAO TanDong CONG ZhiYuan YAN XinLiang KANG ShiChang ZHANG Yong 《科学通报(英文版)》2007,52(10):1405-1413
High mountains may serve as a condenser for persistent organic pollutants. In the present study, soil and grass samples from Mt. Qomolangma region, China were collected from 4600 to 5620 m a.s.I and were analyzed for polycyclic aromatic hydrocarbons (PAHs) to determine if they are concentrated at colder, more elevated sites and to evaluate their possible resources and fractionation. The total PAHs concentration in soil samples was 〈 600 ng g^-1, the critical value to differentiate PAHs levels in remote and urban regions. This implied the PAHs levels at Mt. Qomolangma are relatively low and what one might expect in such a remote region of the world. These low values may represent a soil background for mid-latitude Northern Hemisphere soils away from the direct influence of an anthropogenic source. As for the distribution pattern, the low molecular weight PAHs were prone to accumulate at higher altitude, while the high molecular weight PAHs inversely related or unrelated with elevation. Based on high concentration of phenanthrene at elevated sample site and the ratios of individual PAHs, we deduced that home-heating combustion and vehicle emission may result in the constitution trait of PAHs in this mountain region. Monsoon traveling over India, Pakistan and other countries with dense population may carry contaminant to Mt. Qomolangma region. 相似文献
138.
张毅君 《科技情报开发与经济》2007,17(21):53-54
对校图书馆员"职业高原"现象进行了分析,提出了"以人为本"的管理策略,以帮助高校图书馆员走出"职业高原"期。 相似文献
139.
煤矿井下运输系统管理对策探讨 总被引:1,自引:0,他引:1
蔡旭峰 《科技情报开发与经济》2007,17(10):275-276
分析了煤矿原煤运输系统事故的原因,提出了控制煤矿皮带运输事故的对策和强化皮带运输系统安全管理的措施。 相似文献
140.
本文对一种新型输出波长1.55μm、超高速10 GHz、多量子阱、锁模半导体激光器的自发辐射光谱的蓝移现象进行实验研究,得到随着对锁模半导体激光器增益区施加增益电流的增加(5 mA→70 mA),多量子阱半导体激光器自发辐射光谱存在明显的蓝移现象(1.550μm→1.500μm),以及输出中心波长向短波长方向移动50 nm的实验结果,这对深刻理解和实现光时分复用技术中高质量超短相干脉冲光源具有重要意义. 相似文献