信息技术和教学方式的改革

主要阐述了信息技术给教学方式带来的深远影响，以及21世纪教师掌握和应用信息技术以辅助教学的必要性。     

管理信息系统教学刍议

企业管理的发展变化和计算机信息技术的迅猛发展,给管理信息系统的教学提出了更高的要求,要求管理信息系统的教学体系要不断完善、教学内容要不断充实,教学方式要不断改进。从预备知识的重要性、教学内容的更新、强化案例教学、加强实践环节等方面进行探讨,探索出一条真正有效、切实可行的教学改革之路。     

地理新课程中环境教育的定位、目标与教学策略

地理课程在环境教育中承担主渠道作用。针对目前地理学科教学渗透环境教育模式成效不明显的现状，分析了两者目标的融合性，并提出了有效的教学策略。     

现代信息技术在大学英语教学中的应用

从信息技术的发展趋势入手,分析了信息技术在英语教学中的应用现状,提出了进一步加强信息技术与英语教学整合的措施。     

靖西县新圩铝土矿地质特征及控矿因素

根据多年的实际工柞经验，论述了靖西新圩铝土矿床的地质特征及控矿因素。     

辽宁大学生身体健康状况的调查研究

运用问卷调查、健康检测及数理统计等方法,对辽宁大学生健康状况及影响诱因进行调查分析。结果表明:大学生身体健康状况基本良好,运动目的性呈现多元倾向。部分学生的认识和行为表现不一致,健康知识的知晓度欠缺,导致身体健康水平不高。提出相应改善对策,为高校实施健康教育、科教兴省提供参考。     

深化实践教学改革,构建合理实践教学体系

全面培养高素质的具有创新意识和实践能力的应用型人才是时代发展的需要,也是深化当今教育改革的根本目标。根据普通高校实践教学中普遍存在的问题以及学校目前的实践教学现状,结合我校应用型人才培养目标,深化实践教学改革,构建了较为科学合理的实践教学体系。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

高校艺术体育类学生英语口语教学的探索与实践

高校艺术体育类学生是指在各高校学习音乐、舞蹈、美术、体育等艺术类和体育类专业的非文史理工类大学生。从英语口语教学实践出发，说明教学环境和英语语音学知识与口语能力的提高休戚相关，探讨艺术体育类学生英语口语水平提高之途径。     

开展项目教学,提高教与学质量

项目教学合理的选择了知识内容和教学方法,保证了学生获得相对完整的专业知识和专业能力,所以项目教学既提高了教师的教学素质,同时也提高了学生各方面的能力。