A simulation method of combinding boundary element method with generalized Langevin dynamics

A new simulation approach to incorporate hydration force into generalized Langevin dynamics (GLD) is developed in this note. The hydration force determined by the boundary element method (BEM) is taken into account as the mean force terms of solvent including Coulombic interactions with the induced surface charge and the surface pressure of solvent. The exponential model is taken for the friction kernel. A simulation study has been performed on the cyclic undecapeptide cyclosporin A (CPA). The results obtained from the new method (GLDBEM) have been analyzed and compared with that obtained from the molecular dynamics (MD) simulation and the conventional stochastic dynamics (SD) simulation. We have found that the results obtained from GLDBEM show the obvious improvement over the SD simulation technique in the study of molecular structure and dynamic properties.     

Stretching and imaging studies of single DNA molecules

DNA molecules were stretched on silanized mica surface with the molecular combing technique, and detected with fluorescence microscopy and atomic force microscopy. Meantime, DNA molecules were stretched with a modified dynamic molecular combing technique and studied with atomic force microscopy. The results indicate that, compared with the dynamic molecular combing technique, the modified dynamic molecular combing technique has advantages of less-sample demand and less contamination to sample; as compared with the molecular combing technique, it has better aligning effect and reproducibility. Combination of this kind of DNA molecular manipulating technique with the single DNA molecule detecting technique by atomic force microscopy and fluorescence microscopy will play an important role in the basic research of molecular dynamics and the application of gene research.     

Atomic force microscopic observation on substructure of pollen exine inCedrus deodara andMetasequoia glyptostroboides

The substructure of pollen exine inCedrus deodara (Roxb.) Loud. andMetasequoia glyptostroboides Hu et Cheng has been examined with an atomic force microscope (AFM). The results indicate that the exine substructure units containing sporopollenin in two species are similar in shape, which are granular, but slightly different in size. InCedrus the substructure unit of pollen exine appears to be 56–99 nm long and 42–74 nm wide, while inMetasequoia it appears to be 81–118 nm long and 43–98 nm wide. It has been observed that the subunits of pollen exine inCedrus arranged tightly to form short-rod-like or spheroidal pollen exine units, several or more than ten of which formed an island-like structure. There are various spaces among these island-like structures which are interconnected to occupy the entire pollen exine. InMetasequoia, the subunits of pollen exine also arranged tightly with a distribution tendency of cluster of 3–10, however, no obvious boundary exists among these clusters. From our results, it is concluded that there is no tendency of helical arrangement for the subunits of pollen exine inCedrus andMetasequoia, and the results support Southworth’ view that subunits of pollen exine are granular shape in lattice structure.     

大气海洋油气质点受力分析

从平面入手 ,讨论了地球球面质点在绕太阳运行过程中的受力情况 ,并推得球面质点所受各力的表达式 ,讨论了各力的函数关系及其变化性质 ,对有关各力进行比较归类 ,指出了各力的适应性及存在问题。展望了各力在大气、海洋、油气、板块等运动研究方面的应用前景。     

Stewart平台式六维力测量装置初探

利用Ｓｔｅｗａｒｔ平台结构特点,开必一种新型的六维力测量装置。根据Ｓｔｅｗａｒｔ平台的静力学关系,建立了六维力测量装置的数学模型。给出了Ｓｔｅｗａｒｔ平台上平台所受的六维力和６个支承腿所受拉压力的关系,并进行了结构设计和测量系统设计。     

汽轮机叶片参数的多目标优化设计

由于制造误差和不平衡力的作用,汽轮机叶片的周向气动力除合成一个力倡外,还合成一个横向力,这个横向力使转子发生进动,在一定条件下会使转子失稳,是转子的一个自激激振力。为保证机器正常工作,应对汽轮机叶片参数进行多目标优化、本文首先导出了力偶和激振力的公式,建立了汽轮机叶片参数的多目标优化设计的数学模型,提出了求解该模型的算法,并给出了算例。     

静电磁场中的带电粒子

给出了带电粒子在任意一个均匀静电磁场中的运动方程 ,并依据此结果 ,讨论了几种典型情况     

双向无粘结预应力混凝土井式楼盖的设计研究

双向井字梁盖可在不增加层高的基础上提供大空间及美观的室内天花。本文通过一设计实例较详细介绍了无粘结部分预应力混凝土井字梁结构的方案确定和设计计算。结果表明 ,双向无粘结部分预应力结构合理、施工方便     

一种近似恒力弹簧装置的设计

为消除弹簧装置中应力随应变不断变化而产生的多余应力 ,在卷簧结构中 ,采用螺旋变径输出轮 ,用半径的变化抵消力矩的变化 ,获得近似恒定的输出力 .在精度要求不高的场合 ,采用此方式可形成简便可靠的近似恒力的弹簧装置 .     

考虑基桩承载力差异随机性的承台梁内力分析

提出了一种考虑桩土共同工作的承台梁内力分析方法及确定其桩承地菌的可靠性数理统计方法,结合承机分析理论,提出了考虑基桩承载力随机性的承台梁内力包络图的确定方法,并开发出相应的计算分析软件。