绿色溶剂离子液体在酯合成反应中的应用研究进展

离子液体作为一种绿色溶剂,由于其优良性质,在分离、有机合成及催化反应等领域被广泛应用．本文综述了近年来离子液体作为一种绿色溶剂和催化剂在酯合成反应中的应用研究进展．     

Protein kinase C regulation of GABAA receptors

Pharmacological studies with drugs that activate or inhibit several protein kinase C (PKC) isozymes have identified the PKC family of serine-threonine kinases as important in the regulation of -aminobutyric acid type A (GABA_A) receptor function. PKC modulates GABA_A receptor surface density, chloride conductance and receptor sensitivity to positive allosteric modulators such as neurosteroids, ethanol, benzodiazepines and barbiturates. Recent studies using PKC isozyme-selective reagents and gene-targeted mice have begun to identify critical roles for three isozymes, PKCII, PKC and PKC, in various aspects of GABA_A receptor regulation. Progress in this field touches upon therapeutic areas that are of great clinical importance such as anxiety and addiction. Increased understanding of how PKC regulates GABA_A receptors and which PKC isozymes are involved holds promise for development of new treatments for diverse neuropsychiatric disorders.Received 2 August 2004; received after revision 17 August 2004; accepted 21 August 2004     

丁炔二醇合成反应的颗粒宏观动力学及选择性的研究

本文从理论上分析了均匀分布有金属铜的球形大颗粒催化剂对合成丁炔二醇并-串连反应的影响,並用转框式反应器检验了宏观动力学分析结果。各组分浓度变化的模型计算值与实验测定值的相对误差一般在5%以内。     

一种新型氢化诺卜基双子季铵盐的合成及其抑菌活性研究

该文首先由N,N-二甲基乙醇胺与己二酸反应合成己二酸二(β-二甲胺基)乙酯,然后将己二酸二(β-二甲胺基)乙酯与氢化诺卜基溴按物质的量比例为1.0∶2.1进行反应,合成一种含二元酸酯基的氢化诺卜基双子季铵盐.产物结构用红外光谱、核磁共振(氢谱、碳谱)和质谱进行表征,用菌丝生长速率法评价了该季铵盐化合物对10种植物病原真菌的生长抑制作用.实验结果表明：当药液质量浓度为100.0 mg·L^-1时,该季铵盐化合物对松枯梢病病原菌、烟草黑胫病病原菌、彩绒革盖菌和七叶树壳梭孢菌的抑制率达97.0%～100.0%,远高于百菌清的抑制率,对水稻纹枯病病原菌的抑制率接近90.0%;当药液质量浓度为50.0 mg·L^-1时,该季铵盐化合物对以上5种病原菌的抑制率分别为100.0%、88.8%、86.8%、84.4%和77.2%,均超过对照样百菌清的抑制率.     

香豆素-3-羧酸与1-辛烷磺酸钠共插层LEuH及敏化发光性能?

本文采用水热法合成了NO-3型层状铕氢氧化物(NO3-LEuH),通过离子交换法将去质子的香豆素-3-羧酸和1-辛烷磺酸根离子引入前体LEuH的层间,改变香豆素-3-羧酸和1-辛烷磺酸钠的比例得到了一系列发光强度不同的复合体.采用X-射线粉末衍射仪(XRD),红外吸收光谱仪(IR),和荧光分光光度计(PL)等方法研究了其结构及性质,结果表明香豆素-3-羧酸的插入能有效敏化层板Eu3+的红光发射.     

Mechanism of Citric Acid Crosslinking in Cotton Fabrics

Citric acid (CA), which is cheap and nontoxicity, was regarded as the most likely formaldehyde - free durable press finishing reagent to be commercialized. To improve the drawbacks of CA finishs such as yellowing and less durability to home laundering, further research should be done. In this paper, a method had been found to differentiate ester crosslinkings from ester attachments on CA treated fabric and the variations of both ester crosslinkings and ester attachments under different curing conditions were also studied.     

蜡酯合成酶的研究进展及其应用

蜡酯合成酶（WS）是生物体内蜡酯合成的关键酶，存在于多种动植物和微生物中，该酶可催化生成一系列结构各异、功用不同的酯类化合物。随着对WS的深入研究，人们发现不同物种的WS在功能与活性上有较大的差异，这些差异导致了其合成产物及用途的多样性。本文系统论述了不同生物体内蜡酯的合成途径、WS的生化特性与酶工程改造及其在各种酯类化合物生产中的应用，为WS的进一步研究提供参考依据。     

噻唑烷-4-羧酸苄酯的合成

以L-半胱氨酸为原料,对甲苯磺酸为催化剂,合成L-半胱氨酸苄酯对甲苯磺酸盐,得到L-半胱氨酸苄酯对甲苯磺酸盐合成的较佳条件是：L-半胱氨酸、对甲苯磺酸、苯甲醇的物质的量比为1：1．1：3．7,50mL苯,在此条件下L-半胱氨酸苄酯对甲苯磺酸盐的产率是86．5％。然后用L-半胱氨酸苄酯对甲苯磺酸盐和醛类反应生成相应的噻唑烷-4-羧酸苄酯,产率为72．3％,化合物的结构经^1H NMR,IR,元素分析得以确证,该化合物为新型ACEI的设计与合成提供一种重要的中间体。     

Super-distant molecular hybridization of plant seeds by ion beam-mediated gene cluster

The N beam-mediated distant molecular hybridization between Ginkgo biloba I and watermelon was studied. The results showed that the ester gene of Ginkgo biloba L was successfully expressed in two varieties of watermelon. 3-16 and SR2-14-2, in both of which the ester quantities were measured as 17.0756 μg/g and 45.9998 μg/g respectively. Meanwhile, superoxide dismutase (SOD) activity in leaves of the watennelon expressing ester gene was increased twofold as compared to that of the control, showing that ion beam could mediate distant and/or super-distant donor gene expression in the cells of a receptor. Furthermore, the molecular nechanism of distant hybridization was analyzed.     

对甲苯磺酸催化合成异丁酸乙酯的研究

对甲苯磺酸作为异丁酸和乙醇的酯化催化剂,性能优于硫酸,本文探讨并确定了异丁酸与乙醇酯化反应的最佳条件。