龙王河流域(莒南段)水污染现状及综合治理对策

通过对龙王河流域水质现状评价及主要污染源分析，针对其存在的突出问题，按照目标、总量、项目、投资四位一体的小流域控制思路，本着治、用、保相结合的原则，提出了优化产业结构、污染源治理、废水资源化、生态保护等一系列综合治理对策。     

纳米SiC颗粒SAXS表征及其与 XRD、SEM的比较

对在不同工艺下制备的两组纳米SiC颗粒分别进行了小角X射线散射(SAXS)、X射线衍射(XRD)和扫描电镜(SEM)测试．结果显示，两组颗粒试样存在尺寸和粒度分布差异，不同测量方法所包含的信息各有侧重．利用二维探测器XRD系统进行了SAXS和XRD测量，探讨了该系统在SAXS测量中的数据采集和处理方法，对这些测试结果及其与SEM的结果进行了综合分析比较．发现SAXS更适合于样品尺寸的总体状态表征。能提供更丰富的信息，计算结果更可靠．     

Inducing dopaminergic differentiation of expanded rat mesencephalic neural stem cells by ascorbic acid in vitro

Ascorbic acid (AA) induced differentiation of neural stem cells (NSCs) into dopaminergic (DAergic) neurons is reported.NSCs derived from rat mesencephalon were maintained and expanded in a defined medium containing mitogens of basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF).Compared with the control, ascorbic acid treatment led to more DAergic neuronal differentiation as indicated by the expression of tyrosine hydroxylase (TH) and dopamine transporter (DAT), which are specific markers of dopamine neurons.AA induction also enhanced expression of Nurr1 and Shh.PD98059, an inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway, could block AA-induced Nurr1, TH and DAT mRNA expression.The results might suggest a new strategy to provide enough dopaminergic cells for the therapy of Parkinson's disease (PD), and Nurr1 and ERK signaling pathway might participate in the AA-induced DAergic differentiation.     

论福建省中小企业的跨国经营策略与风险防范

跨国经营是我国企业在全球化的世界经济中求得生存和发展的必然选择.随着我国经济实力的不断增强,中小企业走出国门进行国际化经营的实践活动愈趋活跃,但总体来讲我国中小企业的跨国经营尚处于起步阶段.应在中小企业跨国经营理论的基础上,结合福建省中小企业的特点,对本省中小企业跨国经营策略的内容、思路、特色等进行深入研究,以期更好地引导实践.     

迅速发展的复杂网络研究与面临的挑战

近年来复杂网络的小世界效应、无标度特性和超家族的发现,大大地激起了国内外研究复杂网络的热潮.本文简介了若干研究进展,讨论了当前整个复杂网络研究面临的挑战性问题.     

朱家尖岛滨海小流域湿地的蟹类

研究了朱家尖岛在海堤和水闸建成前,与海洋直接相连的滨海小流域小型湿地蟹类的种类与分布,为今后作进一步探讨湿地与海洋完全分隔后环境和生物多样性的变化提供基础.通过系统的采集,共采集到蟹类11种,分属3科8属,其中8种属于方蟹科,占总数的72.7%,1种属于沙蟹科,痕掌沙蟹遍布高潮区的沙滩.河道中,字纹弓蟹成为该地域内蟹类群落的优势种,而且蟹类分布与周围环境变化有关.水闸建成后,将会对字纹弓蟹等洄游性蟹类产生更大影响.     

Development of the CAS-IBB single-particle microbeam for localized irradiation of living cells

A single-particle microbeam facility has been constructed at the Key Laboratory of Ion Beam Bioengineering (LIBB), Chinese Academy of Sciences (CAS). The system was designed to deliver a defined numbers of hydrogen ions, produced by a van de Graaff accelerator, in an energy range of 2.0-3.0 MeV, into an area smaller than that of the nucleus of an individual living cell. The beam is collimated by a borosilicate glass capillary that forms the beam-line exit. An integrated computer program recognizes the cells and locates them one by one over the microbeam exit for irradiation. We present technical details of the CAS-LIBB microbeam facility, particularly on the collimator, hardware, control program, as well as cell irradiation protocols available. Various factors contributing to the targeting and positioning precision are discussed along with accuracy measurement results.     

土体小应变刚度特性的试验研究

土体的小应变刚度在深基坑或隧道开挖等以变形控制为主的工程中是起决定性作用的参数.利用固结仪、应力路径三轴仪和共振柱联合测定江苏常州地区3个典型土层原状土的小应变刚度特性,得到了土体小应变硬化模型(HSS)的相关参数,包括土体的初始剪切模量、模量退化曲线、土体强度参数、加卸载模量等.分析了土体有效应力对土体小应变刚度特性的影响,并对如何选择合适的小应变模型参数提出了初步建议.     

基于TCMSP抗肿瘤中药小分子EGFR-TKI的研究

目的研究分析中药小分子表皮生长因子受体酪氨酸激酶抑制剂(EGFR-TKI)的抗肿瘤情况。方法挖掘中药系统药理学数据库与分析平台(TCMSP)中药小分子表皮生长因子受体抑制剂,利用反向分子对接服务器(DRAR-CPI)进行靶点验证。结果木犀草素、槲皮素、金雀异黄酮、表没食子儿茶素没食子酸酯、漆黄素5种中药小分子与表皮生长因子受体(EGFR)结合良好。结论中药小分子EGFR-TKI能从多个靶点、多种途径抑制肿瘤细胞的生长和扩散,利用中药小分子开发新一代多靶点EGFR-TKI具有广阔的前景。     

非理性投资者行为的IPO抑价理论分析

借鉴行为金融学中有关投资者非理性行为的观点,对中国广大中小投资者的非理性行为和中国IPO抑价的关系进行了研究.假定发行公司以筹集资金最大化为目标函数,理性的机构投资者作为代理人持有股票,并在上市后把IPO股票转售给非理性的中小投资者,以攫取他们的消费者剩余,达到目的.通过模型化该过程,发现中国的IPO高抑价与中国存在众多的非理性中小投资者有直接的关系,是他们导致了抑价这一结果.