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11.
Huibi Xu Kaixun Huang Xianghu Qu Zhonghong Gao Qiong Liu Runsheng Chen Zhenyu Xuan 《科学通报(英文版)》2001,46(14):1159-1161
The computer program RNA Draw was used to identify the secondary structures in the 3′ untranslated regions (3′UTRs) of the
mRNAs from 46 eukaryotic selenoproteins among 7 species. The program found one or two possible SECIS elements in these selenoproteins.
The SECIS element consists of a stem-loop or hairpin structure with three conserved sequences of AUGA-(A)AA-GA. SECIS element
was not found by the RNA Draw program in randomly selected non-selenoproteins. The results showed that SECIS element is the
unique character of the genes of eukaryotic selenoproteins. Thus it is possible to use RNA Draw to search the SECIS elements
in gene bank for potential new selenoproteins. 相似文献