吉非罗齐胶囊剂的相对生物利用度及其生物等效性评价

１０名健康受试者口服两种不同厂家生产的吉非罗齐胶囊,以高效液相色谱法（ＨＰＬＣ）测定其血药浓度经时过程,经“ＰＫＢＰ－Ｎ１”药动学程序计算表明,湘江制药厂生产的吉非罗齐胶囊与金晓制药厂生产的吉非罗齐胶囊的吸收半衰期ｔ１／２ｋａ分别为（０４２±０１９）和（０４９±０２８）ｈ;消除半衰期ｔ１／２分别为（１４８±０８４）和（１２６±０４５）ｈ;达峰时间ｔｍａｘ分别为（１４５±０３７）和（１６０±０７８）ｈ;达峰浓度ｃｍａｘ分别为（６１８８±１５５１）和（６１５１±１０３４）μｇ／ｍＬ;ＡＵＣ０－∞分别为（２１２９１±４７１６）和（１９９８５±２４９１）μｇ·ｈ／ｍＬ,以湘江制药厂生产的吉非罗齐胶囊为参比测得金晓制药厂生产的吉非罗齐胶囊的相对生物利用度为０９３９。经双单侧ｔ检验法统计分析,表明两制剂间ＡＵＣ无显著差异,两制剂具有生物等效性。     

大立体角多参数电离室

因重离子核物理研究工作研究,研制成功灵敏区深庶３５ｃｍ的大立体角多参数电离室,可同 量信号△Ｅ、Ｅ和位置信号Ｘ、Ｙ等多项参数。     

Milestone of the meridian science──970th anniversary of the Chinese Bronze Statue of Meridian

For more than a thousand years, Chinese people were aware of the transmitted sensations by the application of needles on the body surface. This practice is called acupuncture. Acupuncture had been recorded and transcribed in writings and in drawings, until finally the acupoints were inscribed onto a bronze statue. The bronze statue was called the Meridian Figure. Deeply embodied in the bronze statue is a tripartite confrontation-prism representation of the humans body. This concept was a great scientific achievement in ancient China. The author traces the history of Meridian science described in traditional Chinese medical terms. Then he explores a clear analogy of the meridian pathway (MP) phenomenon. In a model system, by using a simple segmental in vertebrate, certain parallels can be demonstrated with the meridian concept. For example, the author demonstrated a clear correlation rule among the central mechano-sensory channels, and characteristics of positional discrimination in individual nerve cells from different receptive field inputs. The evidence suggests that the MP phenomenon is an objective neurobiological response. To clarify the research objective in this paper, the author suggests that the MP is a bi-directional pathway along which a positional message signal is transmitted. This phenomenon is evoked by physical stimulation, transmitted linearly across the human body segments, and is perceived by the brain. The MP consists of low resistance paths, is connected by the liquid media contained in the apposite membranous structure. At the cellular level, the regulation functions of MP must pass through along this low resistance path. Two aspects of the modern Meridian research are the functional regulation and the mechanism of intercellular liquid modulation at the nanometer level.     

春秋刘国故城考

刘国是春秋时期东周王畿内的重要封国之一。笔者就刘国故城遗址、地望及其兴衰进行了考证     

一个模糊多目标群体决策方法

将多目标系统模糊决策理论推广到多目标标群体决策,给出一个模糊多目标群体决策方法。     

三种国外冷杉的核型研究

首次报道了３种国外冷杉的核型。ＡｂｉｅｓｃｅｐｈａｌｏｎｉｃａＬｏｕｄ。有９对中部着丝粒和３对近中着丝粒染色体,Ａ．ｎｕｍｉｄｉｃａＤｅＬａｎｎｏｎｅｘＣａｒｒ．文中还讨论了３种冷杉及其氯不组的进化地位。     

关于傅科摆相对运动轨迹的讨论

根据傅科摆确定的起始条件,正确导出其轨迹方程,并用计算机画出其相对运动轨迹曲线。同时推证得摆锤在最大幅角位置时,其相对速度为零这一重要特征。     

关于Scott拓扑的core紧性

ＤＣＰＯ Ｌ被称作Σ－ｃｏｒｅ紧的,如果当Ｌ赋以Ｓｃｏｔｔ拓扑后是一个ｃｏｒｅ紧空间,长期以来,从序结构的角度刻划那些Σ－ｃｏｒｅ紧的ＤＣＰＯ一直是悬而未解的问题。在一定的限制条件下讨论上述问题,并得到了一些结果。     

青海高原春小麦籽粒蛋白质积累规律研究

分析了阿勃,青春５３３,青农４６９、青农４５２等四个春小麦品种（品系）在青海西宁地区籽粒蛋白质相对含量的变化规律和蛋白质绝对含量的积累进程,结果表明,从开花至成熟,籽粒蛋白质相对含量的变化呈“Ｕ”型曲线,并以花后籽粒发育初期含量最花,花后３１天左右是该地区春小麦籽粒中蛋白质相对含量最低的时期。不同品种在花后不同时期蛋白质相对含量各不相同;籽粒蛋白质绝对含量的积累过程呈“Ｓ”形曲线,可用概率转换方程     

滇缅公路在抗日战争中的历史地位

滇缅公路是抗战时期，为了战局的需要新辟的一条重要交通干线，不仅对我国的抗战和世界反法西斯战争的胜利起了积极作用，而且对云南地方经济的发展和边疆少数民族地区的开发也产生了巨大的影响。