生物组织中光敏剂浓度的非侵入式测量

用反射式分光光度计测量生物样品表面背散射光的变化能够调定作品内光敏剂浓度，本文把光子迁移模型理论用于该方法．测量灵敏度与已有的扩散理论的结果比较表明，光子迁移模型理论可用于光敏剂浓度的确定．     

Modulation of low-frequency oscillations in GaAs MESFETs’ channel current by sidegating bias

Low-frequency oscillations in channel current are usually observed when measuring the GaAs MESFET‘s output characteristics. This paper studies the oscillations by testing the MESFET‘s output characteristics under different sidegate bias conditions. It is shown that the low-frequency oscillations of channel current are directly related to the sidegate bias. In other words, the sidegate bias can modulate the oscillations. Whether the sidegate bias varies positively or negatively, there will inevitably be a threshold voltage after which the low-frequency oscillations disappear. The observation is strongly dependent upon the peculiarities of channel-substrate (C-S) junction and impact ionization of traps-EL2 under high field. This conclusion is of particular pertinence to the design of low-noise GaAs IC‘s.     

Monte Carlo方法研究光子在有界肿瘤组织中的分布

目的研究有界肿瘤组织中光子分布特性。方法通过建立光在有界肿瘤组织中传输模型,用蒙特卡罗方法模拟光子在有界生物组织的传输,与半无限大肿瘤组织中光子分布的特性对比,分析光子在有界肿瘤组织中的分布特性。结果肿瘤组织中光子能量密度分布在纵向和横向基本是按负指数规律变化,但沿纵向在入射表面附近有极值点,当取定较小边界范围时,光子能量密度增加,组织内的有效光子数下降。结论有界肿瘤组织光子能量密度沿纵向和横向变化规律与半无限大组织变化规律相似,肿瘤组织边界影响光子在生物组织的能量密度和有效光子数分布。     

鲍鱼多糖Hal-B的乙酰解研究

对鲍鱼中分离得到的硫酸脂多糖Hal—B进行了乙酰解的研究。硅胶柱层析分离得到两个组分，核磁共振和串联质谱的研究表明：这两个组分分别是全乙酰化的半乳糖和全乙酰化的寡糖混合物。     

电离放电特征参量时空演变规律及其除尘应用的基础研究

本文详细介绍了电除尘技术的研究现状、现存问题及其研究趋势。认为目前电除尘技术的理论尚不完备,基本上还处于20世纪60年代的水平,属于经验工程的学科。并为此,本文深入研究了大气压电场电离放电特征参量的时空演变规律、电离放电通道中的带电粒子复合及其输运特性等,以便解决目前除尘电场的电离占空比、带电粒子输运项甚低等问题。进而强化了烟尘的荷电、凝聚物理过程,这将大幅度提高烟尘的驱进速度和除尘效率。     

Sequencing of phosphopeptides sulfonated by 4-sulfophenyl isothiocyanate using post-source decay matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Phosphorylation/dephosphorylation is probably the most common and important reversible post-translational modification of proteins. Analyzing the functional effects of phosphorylation is helpful for understanding the biological functions of proteins. Identification of the phosphorylation sites of phosphorylated protein is a prerequisite for research on phosphorylation. In this work, an effective and simple method of identification of protein phosphorylation sites has been developed. Phosphopeptides were selectively enriched with immobilized metal affinity chromatography (IMAC) and subsequently chemically modified by 4-sulfophenyl isothiocyanate, and then the chemically modified phosphopeptides were sequenced with post-source decay (PSD) matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry for detecting phosphorylation sites. The charge of derivatization by 4-sulfophenyl isothiocyanate introduces a negative sulfonic acid group at the N-terminus of a peptide, and enables the selective detection of only a single series of C-terminal y-type ions. This chemically assisted method greatly simplifies the extremely complex pattern of PSD fragment ions and makes the PSD spectra more easier to be interpreted. The phosphorylation sites of a synthesized model phosphopeptide and human c-myc protein have been successfully identified by this method.     

基于GATE程序的MicroSPECT成像系统并行化Monte Carlo模拟

MicroSPECT(micro single photon emission computed tomography)是专用于小动物成像的分子核医学设备。为了准确研究复杂放射源分布条件下光子在MicroSPECT成像系统中的输运过程,使用GATE程序模拟了基于H8500位置灵敏光电倍增管和针孔准直器的MicroSPECT系统,并在清华高性能计算集群上实现了GATE程序的并行化模拟。通过并行计算有效地提高了模拟速度,分别获得了点源、线源、Derenzo模型、Moby模型的投影数据及用于迭代断层图像重建的系统点扩展函数(point spread function,PSF)数据。     

光电子成像:走向新的世纪

半个世纪以来,光电子成像(主要包括微光成像和热成像)技术取得了惊人的发展,显示出极为辉煌的前景.在微光成像技术方面,发展了一代、二代和三代直视像增强技术,真空和固体微光摄像技术及光子计数成像技术;在热成像技术方面,发展了致冷型一代、二代和三代热成像技术和非致冷型列阵热成像技术.回顾光电子成像技术自1930年以来的进展,展望新世纪中微光四代像增强技术、新型微光摄像技术和先进的焦平面(FPA)和非致冷型热成像技术的发展.     

微波场影响生物体超弱发光的研究

根据F.A.Popp相干理论及有关实验，生物光子的延迟辐射强度时间服从双曲函数分布，通过对蒜瓣在微波作用下超弱发光的研究表明，并非所有生物体的发光曲线都呈双曲衰减，有些生物体的超弱发光呈振荡趋势。考虑到声子和光子的相互作用，并通过实验和计算机模拟验证这一结果。     

电场处理对牧草种子超弱发光的影响

生物系统超弱光子辐射值是生物系统内物质代谢和能量转化活动的一项指标.我们用电场处理牧草种子,测定电场对种子的超弱发光值的影响.结果表明,电场处理种子明显影响种子的超弱光子辐射强度,不同电场处理条件对种子的超弱发光值影响不同.在0.5～5.5kV/cm场强范围内,超弱发光值随场强增加呈非单调型变化.