Interaction of Apolipoprotein H with Phospholipid Membranes : a Monolayer Study

ＩｎｔｒｏｄｕｃｔｉｏｎＡｐｏｌｉｐｏｐｒｏｔｅｉｎＨ（ＡｐｏＨ）ｉｓａｐｌａｓｍａｇｌｙｃｏｐｒｏｔｅｉｎｂｅｌｏｎｇｉｎｇｔｏｔｈｅｆａｍｉｌｙｏｆａｐｏｌｉｐｏｐｒｏｔｅｉｎｓ．Ｉｔｗａｓｄｅｓｃｒｉｂｅｄｆｏｒｔｈｅｆｉｒｓｔｔｉｍｅｉｎ１９...     

Interaction of 80S Rat Liver Ribosome with Lipid Monolayers Studied by Electron Microscopy

ＩｎｔｒｏｄｕｃｔｉｏｎＲｉｂｏｓｏｍｅｓ，ｗｈｉｃｈａｒｅｈｉｇｈｌｙｃｏｍｐｌｅｘｏｒｇａｎｅｌｅｓｆｏｒｍｅｄｂｙｔｈｅａｓｓｅｍｂｌｙｏｆｐｒｏｔｅｉｎｓａｎｄｎｕｃｌｅｉｃａｃｉｄｓ，ｅｘｉｓｔｉｎｎｅａｒｌｙａｌｋｉｎｄｓｏｆｃｅｌｓ．Ｔ...     

甲酸钠的抗氧化作用

以溶血试验、红细胞还原型谷胱甘肽测定、受照南粒ＰＵＣ１８ＤＮＡ单链断裂的测定、受照小鼠肝和肾匀浆脂质过氧化物的测定作为指标，检测了甲酸钠的抗氧化作用。结果表明：甲酸钠能显著地降低受＾６０Ｃｏγ射线照射的红细胞的溶血水平；显著抑制ＶｉｔＣ／Ｆｅ＾＋＋诱导的红细胞悬液还原型谷胱甘肽的耗竭；显著抑制受质粒ＰＵＣ１８ＤＮＡ单链断裂程度；显著地抑制受照小鼠肝、肾匀浆丙二醛水平的升高，结果提示：内具有抗氧化作     

汉、维吾尔、哈萨克三民族血脂与脂肪肝的关系分析

为探讨汉、维吾尔、哈萨克三个民族患脂肪肝发病情况及是否存在差异.采用超声诊断仪对脂肪肝进行检测,并测定血脂四项.结果显示受调查1152人中,患有脂肪肝379人,其中大多数血脂异常.由此可知脂肪肝在不同民族之间分布不同,脂肪肝患者中血脂异常是其危险因素.     

海洋深层水与褐藻糖胶配伍应用抑制HepG2肝细胞脂质积聚调节作用的研究

以Hep G2细胞为模型,研究海洋深层水(deep sea water,DSW)与褐藻糖胶(fucoidan,FPS)配伍应用对Hep G2细胞脂质代谢的调节作用。采用MTT法确定与DSW配伍应用的FPS浓度控制在50μg/m L以内。在这一范围内,随着FPS浓度的增加(分别为5,10,20,50μg/m L),Hep G2细胞胞内的脂质含量逐渐降低,呈现明显的剂量依赖关系。而且,DSW与50μg/m L的FPS配伍应用的效果显著优于单用同剂量的DSW或FPS。实验结果表明,DSW与FPS配伍应用对Hep G2细胞脂质代谢具有更好的调节作用,其最佳配伍应用浓度为50μg/m L,这为高脂血症的防治提供了一个新的思路。     

Identification of high-lipid producers for biodiesel production from forty-three green algal isolates in China

To identify some desirable algal strains for our future research and/or the production of algae-based biofuel,43 green algal strains were successfully isolated from Chinese freshwaters,and then incubated in the laboratory bioreactors for the growth and oil accumulation investigations.During a 15 d incubation experiment,the accumulations of their biomass and total lipids,together with the lipid productivities for these green algal strains were systematically investigated and compared.Results indicated tha...     

Relationship of phosphatidylcholine to hydrophobic surfactant on rat intestinal chylomicron secretion

Hydrophobic surfactants such as Poloxalene inhibit triglyceride secretion into lymph by enterocytes. The inhibitory effect of these agents on triglyceride secretion is reversed when lipid presented for absorption is exclusively in the form of phosphatidylcholine (PC) and not triglyceride. The present investigation performed in conscious mesenteric lymph fistula rats was designed to determine whether various mixtures of triglyceride and PC given intraduodenally with Poloxalene would also reverse the inhibitory effect of Poloxalene on triglyceride secretion into lymph. A 50–50 mixture of triolein (TO) and PC resulted in normal triglyceride secretion into lymph. However, when the mixture of lipids was 75-25, TO to PC, results for triglyceride recovery in lymph were considerably reduced. The transport rate for triglyceride into lymph was not as depressed, however, as observed for Poloxalene treated rats given lipid for absorption basically in the triglyceride form. Substitution of phosphatidylethanolamine for PC had no beneficial effect on triglyceride secretion in Poloxalene treated rats. It is concluded that PC can reverse the inhibitory effect of Poloxalene on triglyceride secretion into lymph even when considerable amounts of triglyceride along with PC are presented for absorption.     

Role of lipid peroxidation in ferric lactate-enhanced calcium uptake by Ehrlich carcinoma cells

Comparison of Ca²⁺ uptake by Ehrlich carcinoma cells in presence of ferric lactate or aluminum lactate, and formation of thiobarbituric acid-reactive substances, suggests that lipid peroxidation is associated with but not the cause of calcium overload that can lead to cell injury and death.     

橡胶种子油治疗220例高脂血症患者的疗效分析

近年来我们进行了一系列动物实验研究,证实橡胶种子油具有降低血脂和抗动脉粥样硬化的作用,并促进动脉粥样硬化的消退。为验证它的临床疗效,先后选择220例高脂血症患者用精制的橡胶种子油进行治疗。结果证明:橡胶种子油具有良好的降血脂疗效,为当前降低血脂,防治动脉粥样硬化提供了新的途径。