化学修饰碳糊电极及其在药物分析中的应用

对化学修饰碳糊电极（CMCPE）的发展、制备与性能、富集机理、活化和再生及其在药物分析中的应用等进行了综述，并展望了其发展前景。     

室温固相法制备高纯超细氢氧化铝

用室温固相法制备了形状为纤维状，直径约为1—10nm，长度约为30—200nm的超细氢氧化铝，并运用粒度分析仪、X射线粉末衍射(XRD)、电感耦合等离子发射光谱仪对超细粉末进行了分析和表征,此方法具有操作方便，合成工艺简单，污染少等特点。     

泡沫铝的研究现状与应用展望

泡沫铝的多孔结构和金属特性使其在吸声、减震、过滤厦热交换等方面具有优异的性能。介绍了目前国内外泡沫铝的研究进展和基本制备方法，描述了泡沫铝的结构厦特殊性能，并分析了现存工艺、发泡机理及性能分析等方面问题，对泡沫铝在各个领域的应用进行了展望。     

急性小脑性共剂失调临床诊断与治疗

对24例患急性小脑共剂失调的患儿进行临床诊断和临床治疗,达到预期的临床治疗效果.     

一种适用型电子显微镜用钨阴极

本文介绍了一种采用国产钨丝材料做成的电子显微镜用的直热式钨阴极——DWY阴极。简要地介绍了它的制备工艺及主要特性。实践表明DWY阴极是一种具有推广价值的适用型电子显微镜用阴极。     

Preparation and Performance of Bipolar Membranes with Liquid Ion-Exchange Medium

The current density is rather low in solid bipolar membranes, because the water transfer rate is relatively slow across solid bipolar membranes made of solid ion-exchange materials. This paper describes the use of polymer solutions, such as phosphatic poly(vinyl alcohol) solution, poly(acrylic acid) solution and poly(vinyl alcohol) solutions with dispersed cation/anion-exchange resin particles to prepare bipolar membranes. The 0. 1 mol/L NaOH and the 0.05 mol/L H2SO4 were used to test the performance of the bipolar membranes. For a fixed liquid layer thickness, both the current density and the selectivity increase with the concentration increase of a polyelectrolyte solution. The maximum current density measured in the experiment was 1497A/m^2 with a selectivity of 96.8%.     

大麻药总皂苷滴丸制备工艺及溶出度研究

为确立大麻药总皂苷滴丸的最佳成型工艺并考察其溶出度,以滴丸的成型率为评价指标,对大麻药滴丸基质与冷却剂的选择、大麻药与基质的配比、滴制的温度、滴距、滴速进行了单因素分析,并在此基础上以正交试验通过丸重差异、溶散时限和外观质量3个指标对上述主要影响因素进行了优选,采用转篮法和HPLC测定了其溶出度和含量.结果表明:大麻药总皂苷滴丸的最佳工艺条件为B3A1C1D2,即药物基质质量比为1∶4,PEG4000-PEG6000基质质量比为2∶1,滴制温度为70℃,滴距为5 cm,此条件下滴丸各项指标最好.说明该工艺简便可行,评价指标可靠合理,滴丸溶出度良好,符合2010年版中国药典对滴丸制剂的要求.     

Enzymatic activity and chromatographic characteristics of the cell membrane immobilized on silica surface

A new cell membrane preparation. silica carrier cell membrane (CCM), has been presented, in which cell membrane was immobilized on silica which acted as carrier by the absorption. The surface characteristics of the silica CCM have been tested by a scanning electron microscope and surface energy spectrometer. Comparison has been made of the changeable rule of enzymatic activity of rabbit red cell membrane in three states: the silica CCM, the suspension and the precipitation cell membranes, with temperature and time. The result showed that the silica CCM still keeps the same enzymatic activity as the other two states of cell membranes. The interactions between calcium antagonists and rabbi red and cardiac muscle cell membranes, and the stereoscopic interactions between dihydropridines and rabbit cerebellar cell membrane have been investigated by the chromatographic system of the silica CCM as a stationary phase. From the foregoing results, the chromatographic parameters obtained from the system would be expected to indicate the special interaction and enantioselectivity between drugs and membrane receptorsin vivo.     

黑脉羊肚菌培养条件选择及原生质体的制备

探讨了黑脉羊肚菌的培养条件和原生质体的制备.结果表明,洋葱液体培养基适合黑脉羊肚菌生长.培养3d的黑脉羊肚菌菌丝体在30℃下,用4%溶壁酶酶解2 5h,原生质体数目为2 53×106个/mL.     

乌索酸滴丸剂的制备工艺及其质量评价

采用滴制法制备乌索酸滴丸,以滴丸的圆整度、质量差异及硬度等作为综合评定指标,优选出滴丸的最佳工艺为乌索酸与基质配比为1∶5,滴制温度为90℃,滴距为10 cm,冷凝剂的温度为15℃.同时采用RP-HPLC法测定滴丸中乌索酸含量为(5±6.1%)mg,乌索酸滴丸的体外溶出度75 min内比片剂提高232.8%,比乌索酸胶囊提高12.5%.