带卷夹钳的设计与仿真分析

以分析力学为基础对某夹钳进行了理论设计，提出了夹错初始工作阶段的动态反馈过程，得出了夹钳可靠运行的条件，并借助C^＋＋对理论计算获得的核心技术参数进行了优化。以ADAMS为平台对该夹钳建立了虚拟样机，通过仿真分析，验证了设计机构的实用性和理论设计的正确性，为同类产品的改进设计提供了参考。     

U型钢可缩性支架的初始缩动条件

Ｕ型钢可缩性支架的缩动与否，取决于支架卡缆预紧力及搭接部分两端的内力。本文根据Ｕ型钢可缩性支架搭接部分的传力特点和摩擦条件，建立了Ｕ型钢可缩性支架的缩动准则，为支架的力学分析及支护参数的确定提供一种理论根据。     

Patch clamp technique and biophysical study of membrane channels

Summary The present work describes the patch clamp technique, which first allowed the recording of single channel currents in biological membranes. In particular, it describes procedures for preparation and applications of the four different patch clamp configurations. Briefly, the cell-attached configuration is widely used for investigating channel modulation by transmitters acting via second messengers. The cell-free configurations (inside-out and outside-out), complementary to one another with respect to the orientation of the membrane surface, are particularly indicated for the study of the biophysics (kinetics, conductivity, selectivity, mechanism of permeation and block) of ionic channels. Finally, the whole-cell configuration which, because of the remarkable feature that it allows voltage clamp of very small cells, has given access to a number of physiologically important preparations never studied before.     

重载钢轨磨耗预测模型及接触斑网格密度研究

基于车辆-轨道耦合动力学及轮轨滚动接触分析,结合材料磨损理论建立了钢轨磨耗预测模型,编制了计算程序,可实现钢轨磨耗具体分布及发展的定量预测分析.鉴于轮轨接触斑离散化网格密度在预测模型中的显著影响作用,从接触力、磨耗分布等方面对这一因素的影响机理进行分析,探讨合理的接触斑网格密度.研究结果表明:网格密度不影响计算结果的正确性,但是稀疏的网格密度得到的蠕滑力及磨耗分布存在较多尖锐形状突变,增大密度可提高精度及磨耗分布平滑性,但会成倍增加计算代价;网格密度20×20时,钢轨磨耗速率变化由剧烈趋于稳定,继续增大密度改善效果已不明显,建议预测模型中接触斑网格密度取20×20,在确保精度的同时尽可能拥有较高计算效率.     

一个三维食饵,捕食者,小区域模型

本文探讨一个食饵、捕食者、空小区域之间关系的模型.研究一个三维非线性微分方程组论证它的平衡点的稳定性和周期解的存在性.     

索夹对自锚悬索桥成桥状态影响分析

基于有限单元法(FEMC)比较分析了索夹对自锚悬索桥成桥状态的影响.索夹能够提高中跨主缆的成桥线形,在维持索长不变的情况下,各吊杆的成桥索力会有所增大,若使各吊杆均达到设计成桥索力值,则需增大各吊杆的无应力长度值.基于计入索夹影响的FEMC模型分别讨论了索夹长度、截面面积和惯性矩等参数对结构成桥状态的影响,并且建立了根据索夹长度比和面积比计算得到的主缆中跨跨中控制点成桥高程提升量和吊杆索力平均增量值的简化计算公式.经工程实例验证,提出的索夹模型计算结果与结构实际变形接近.     

Development of planar patch clamp technology and its application in the analysis of cellular electrophysiology

A patch clamp chip, as a novel cell-based chip for electrophysiological recordings, has many prominent advantages such as high resolution, accuracy, high throughput and automation. It can be used to perform multivariate and real-time measurements of cell networks in situ. Therefore, this technology will dramatically promote the research on ionic channels, neuronal networks and the application of this technology in drug screening. This paper reviews the development of planar patch clamp technology and its applications in detail. The latest progress in the research of taste cells electrophysiology and taste transduction is also presented. Finally, this paper analyzes the methodology of neural chips. Based on the current research of our laboratory, the prospective applications of a patch clamp chip in the research of taste sensation and transduction mechanisms at molecular and cellular levels are discussed.     

等参双线性元的ZZ超收敛理论分析

分析了ＺＺ超收敛方法，从理论上证明了用等参双线性元求解两阶偏微分方程时，有限元解具有ＺＺ超收敛性。     

Integrating Automatic Patch Snatching System by the Concept of Generalized Mechanisms

An automatic patch snatching system is described which has three machine cells including dividing equipment, tackling equipment and patch removing equipment. The electromechanical integration design of in-piece tackling system based on the concept of generalized mechanisms is introduced. The design of the dividing equipment, the design of micro.feeding machine equipped with micro-level pressure sensor, and the realizing of computer path for patch snatching are investigated.