反式2—呋喃硝基乙烯与二甲胺加成中间体结构的MO研究

在LCAO-SCF-MO-AM1水平上研究了反式2-呋喃硝基乙烯同二甲胺亲核加成反应中间体的结构和性质,从理论上证实了该中间体是一个极性两性离子。     

PKCα反义RNA对乳腺癌细胞增殖及cyclinD1和CDK4表达的影响

ＰＫＣ,ｃｙｃｌｉｎ和ＣＤＫ基因直接参于调控细胞的增殖与分化,因此它们在细胞癌变中的作用已成为重要的研究课题。利用反义ＲＮＡ技术抑制ＰＫＣａ基因的表达,然后观察分析了乳腺癌细胞增殖的变化以及对ｃｙｃｌｉｎＤ１和ＣＤＫ４基因表达的影响。     

Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives

Despite the considerable progress in modern tumor therapy, the prognosis for patients with glioblastoma, the most frequent malignant brain tumor, has not been substantially improved. Although cytoreductive surgery and radiotherapy are the mainstays of treatment for malignant glioma at present, novel cytotoxic drugs and immunotherapeutic approaches hold great promise as effective weapons against these malignancies. Thus, great efforts are being made to enhance antitumoral efficacy by combining various cytotoxic agents, by novel routes of drug administration, or by combining anticancer drugs and immune modulators. Immunotherapeutic approaches include cytotoxic cytokines, targeted antibodies, and vaccination strategies. However, the success of most of these experimental therapies is prevented by the marked molecular resistance of glioma cells to diverse cytotoxic agents or by glioma-associated immunosuppression. One promising experimental strategy to target glioma is the employment of death ligands such as CD95 (Fas/Apo1) ligand or Apo2 ligand (TRAIL). Specific proapoptotic approaches may overcome many of the obvious obstacles to a satisfactory management of malignant brain tumors. Received 8 March 1999; received after revision 27 May 1999; accepted 14 June 1999     

两类积图的(2,1)-全标号

图G的一个k-(2,1)-全标号是一个映射f:V(G)∪E(G)→{0,1,…,k},使得任意2个相邻的点和相邻的边有不同值,且任一对相关联的点和边的值差的绝对值至少为2.G的(2,1)-全标号数λt2(G)定义为G有一个k-(2,1)-全标号的最小的k值.刻画了圈与圈、路与路笛卡尔积图的(2,1)-全标号数.     

新经济下企业文化再造初探

新经济是以新技术、新知识等资源为基础的经济。新经济使企业文化生存面临种种挑战,也随之发生深刻的变革。实施企业X再造进而达到文化再造将是新经济下形成具有核心竞争力的创新性企业文化、推动企业前进的源动力。     

农业高职高专"顶岗学习"的研究与实践

探讨农业专业如何实现理论与实践的结合，学习与就业的结合，课堂与岗位的结合，提高学生的岗位职业能力。提出了学校与就业岗位实现“零距离”的运作模式。     

纳米陶瓷材料制备中的烧结技术

本文主要结合纳米陶瓷的制备工艺,对常见的纳米陶瓷烧结技术的特点和应用进行了综述.     

用单板机实现管道燃气的自动控制

运用AT89C51单片机技术，采用IC卡实现对燃气的预收费、报警、防止非法用气、用气数量显示。并通过网络实现自动化管理。     

一类时滞微分方程的全局吸引性

主要研究一类拟单调时滞微分方程渐近性态，给出方程存在全局吸引正平衡态的充分条件．推广了已有的相应结论．