扁窦形短指软珊瑚中的多羟基甾醇

从采白海南三亚附近海域的扁窦形短指软珊瑚Sinularia depressa Tixier-Durivault中分离鉴定出2种多羟基甾醇化合物。通过光谱分析确定它们分别为胆甾—7—烯—2β，3β，14μ，20β，22α，25—六羟基—6—酮，麦角甾—24(28)—烯—3β，5α，6β—三醇。前属于昆虫蜕皮激素，又称蜕皮甾酮。蜕皮甾酮主要存在于陆地植物中，这是从扁窦形短指软珊瑚中分离到蜕皮甾酮的首次报道。     

Monitoring of Cerebral Oxygenation by Near-infrared Spectroscopy during Cardiopulmonary Bypass in Infants

Objective： To evaluate the use of near-infrared spectroscopy for monitoring cerebral oxygenation under different cardiopulmonary bypass models. Method： Twenty-four patients with ventricular septal defect and pulmonary hypertension undergoing open-heart surgery were assigned eight each to three groups, with respect to different cardiopulmonary bypass models： moderate hypothennia cardiopulmonary bypass, deep hypothennia low flow and deep hypothennia circulatory arrest. For each patient, cerebral oxygenation with near-infrared spectroscopy were monitored and the relative concentration changes in cerebral oxygenated hemoglobin, deoxygenated hemoglobin and oxidized cytochrome aa3 were calculated. Electroencephalography, biochemical indicators such as neuron-specific enolase and lactate, and performed correlation analyses for nearinfrared spectroscopy data and biochemical indicators were also measured. Results： Near-infrared spectroscopy data and biochemical indicators for moderate hypothennia cardiopulmonary bypass and deep hypothennia low flow group showed no correlation. For deep hypothennia circulatory arrest group, oxygenated hemoglobin signal declined to a plateau （nadir） during the circulatory arrest period. The duration from reaching nadir until reperfusion ＂oxygenated hemoglobin signal nadir-time＂, and the minimum values of oxygenated hemoglobin, and oxidized cytochrome aa3 were closely correlated with increasing neuron-specific enolase and lactate. And, all patients whose oxygenated hemoglobin signal nadir-time was less than 35 rain were free from behavioral evidence of brain injury. Conclusion： Near-infrared spectroscopy data including oxygenated hemoglobin signal nadir-time and the minimum of oxygenated hemoglobin and oxidized cytochrome aa3 showed strong correlation with other cerebral function assessment for deep hypothermia circulatory arrest. Oxygenated hemoglobin signal nadir-time determined by near-infrared spectroscopy can be useful in predicting the safe duration of circulatory arrest.     

南海红树内生真菌1947号代谢产物研究(Ⅱ)

首次研究了分离自香港红树Kandelia candel嫩叶的一株红树内生真菌（菌株编号1947）的代谢产物,从菌丝体共分离纯化得到3个化合物,经波谱解析或与标准样品对照分别鉴定其结构为1个神经酰胺——（5E）-N-十六碳酰基-2-氨基-1,3-二羟基-5-十八碳烯（A）和2个甾醇类化合物——过氧化麦角甾醇（B）和麦角甾醇（C）.     

上海地区2017年夏季大气中羰基化合物的空间分布特征

使用实验室自主研发的多通道含氧挥发性有机物(oxygenated volatile organic compound,OvOC)远程控制采样器,于2017年8月4-7日对上海地区20个监测站点在早高峰(6:00-9:00)时段同步采集大气中20种羰基化合物,并利用2,4-二硝基苯肼(dinitrophenylhydra...