大剂量超声波对人骨肉瘤组织灭活作用的研究

为配合瘤段骨超垢灭活再植与瘤细胞培养敏感药物治疗骨肉瘤研究，并探讨超声疗法在骨肉交界呆肢治疗中的重要作用，通过选用新鲜人骨肉瘤组织标本，采用瘤组织碱性磷酸酶染色分级计数和瘤细胞存活度计数方法，研究判定体外医用灭菌剂量超声波在不同溶液介质和作用时间内，对人骨肉瘤组织的杀伤和灭活作用。     

589nm可调谐法拉第反常色散滤光器特性分析

考虑到钠原子Ｄ２线（３Ｓ１／２→３Ｐ３／２）５８９ｎｍ的超精细结构，以及具有Ｖｏｉｇｔ线型的左右旋园偏振谱线的贡献，我们对钠原子气体的法拉第反常色散滤光器的透过率、中心频率移动、通频带宽等跟外加纵向磁场强度、原子汽室温度的关系进行了理论分析．结果表明：该滤光器的中心工作频率磁场调谐能力约为８０ＧＨｚ／Ｔ，通频带宽为０．００１～０．０１ｎｍ，透过率约可达１００％．     

双线纵向激励F^＋2型色心激光器的激励尺寸效应

探讨了双线纵向激励Ｆ＾＋２型色心激光器在不同泵浦光，辅助光和振荡光的束腰半径之经下的增益特性。研究表明，为获得较高基模比例的激光输出和较高的泵浦光利用效率，泵浦光的束腰半径应选择略小于振荡的束腰半径，辅助光的束腰半径应泵浦光的束腰半径近似相等。     

具有转向点的积分微分方程奇摄动非线性边值问题

本文对一类具有转向点的Volterra型积分微分方程奇摄动非线性边值问题,证明了解的存在性并给出了解的一致有效渐近估计。     

纳米硅薄膜中量子点的库仑阻塞效应

用纳米硅薄膜制成了共振隧穿量子点二极管，在77K温度下对其I－V特性进行了测量，得到了具有共振隧穿特征的实验结果。对实验结果分析表明，纳米尺寸晶粒构成的量子点具有库仑阻塞效应。     

嵌岩桩极限承载力的非线性分析

本文根据桩土之间的相互作用 ,采用邓肯 -张模型对土、基岩进行非线性有限元分析 ,计算出桩、土的内力、变形以及承载力 ,理论计算结果与实测情况比较接近。同时据实测结果 ,对照规范提出建议。图 3,表 2 ,参 3。     

pH effect of· OH radical induced oxidation of phosphoryl- methionine in aqueous solution

Conclusion The results of pulse radiolytical research on the · OH radical-induced oxidation of NDM in aqueous solution demonstrate that pH value has a great influence on the radiolytical mechanism of NDM. At low pH value, the product is mainly stabilization of the oxidizing sulfur centre in the three-electron-bonded cation radical NDM₂ ·⁺ [S]; with the increase of pH value, NDM₂ ·⁺ [S] gradually decays to become the reducing α-amino radical which was verified by the chemical method and whose yield was also calculated. Compared with Met₂ ·⁺ [S] produced by the · OH radical-induced oxidation in aqueous solution [1], the stability of NDM₂·⁺ [S] increases and the yield of α-amino radical decreases. This suggests that the introduction of phosphoryl group has a coordinating effect on the radioprotection of methionine to biological systems, and provides the essentially theoretical foundation for the thorough clarification of the reversible phosphorylation of proteins.     

The strong cooperativity of dioxygen binding by dicobalt (II) diporphyrin compounds in nonaqueous solution at room temperature

Thermodynamic data were determined for the reversible binding of O₂ to two compounds of dicobalt(II) di(meso-tetra-phenyl)porphyrin derivatives with different lengths of diamidoaliphatic bridge (abbreviated to Co₂PP₈ and Co₂PP₄) in N,N-dimethylformamide at room temperature. The partial pressure of dioxygen necessary for half-oxygenation (P _1/2) and hill coefficient (n) at 298 K were determined as follows:P _1/2=54.2 kPa,n=2.0 for Co₂PP₈ andP _1/2=6.8 kPa,n=1.8 for Co₂PP₄, respectively. The rate equations of reversible oxygen binding by Co₂PP₈ were determined and the reaction path was proposed. The results of ther-modynamic and kinetic studies indicate that there exists strong cooperative effect during oxygenation of the compounds. The ESR observation reveals that the dioxygen complexes formed in the solutions are of superoxo (Co-O ₂ ⁻ ) type. Supported by the Research Foundation of the State Education Commission of China Zhou Xiaohai: born in 1962, Ph.D. Associate professor