椎间孔镜技术联合选择性神经根阻滞治疗腰椎间盘突出症的疗效研究

为研究椎间孔镜技术联合选择性神经根阻滞治疗腰椎间盘突出症的疗效.回顾性分析本院2015年1月—2019年12月采用椎间孔镜技术联合选择性神经根阻滞治疗120例腰椎间盘突出症患者的临床资料.术后随访6个月,观察并记录术中情况、并发症发生情况及术后6个月采用Macnab量表评价手术疗效.结果表明:120例患者均顺利完成手术...     

Chitosan Conduit for Peripheral Nerve Regeneration

ＩｎｔｒｏｄｕｃｔｉｏｎＴｒａｎｓｅｃｔｉｏｎｉｎｊｕｒｅｄｐｅｒｉｐｈｅｒａｌｎｅｒｖｅｈａｓａｌｗａｙｓｂｅｅｎｄｉｆｆｉｃｕｌｔｔｏｒｅｐａｉｒ .Ｃｌｉｎｉｃａｌｍｅｔｈｏｄｓｉｎｃｌｕｄｅｅｐｉｎｅｕｒｉｕｍｓｕｔｕｒｉｎｇ (ｕｓｅｄｆｏｒｓｌｉｇｈｔｌｙｉｎｊｕｒｅｄｎｅｒｖｅｓ)ａｎｄａｕｔｏｇｒａｆｔ (ｕｓｅｄｆｏｒｓｅｖｅｒｅｌｙｌａｃｅｒａｔｅｄｎｅｒｖｅｓ) .Ｕｎｆｏｒｔｕｎａｔｅｌｙ ,ｂｏｔｈｍｅｔｈｏｄｓｈａｖｅｄｉｓａｄｖａｎｔａｇｅｓｓｕｃｈａｓｎｅｒｖｅｄｉｓｔｏｒｔ…     

TDLS的描述方法

用有向图,有限自动化,神经网络对思辨逻辑系统（ＴＤＬＳ）进行了描述。     

空化初生的热力学影响研究

从非平衡态热力学理论出发,建立了有相变发生时球形气核与围流液体之间能量流和物质流的方程式．在此基础上,确定了自由气核空化初生的条件,并结合气泡动力学对此进行了深入的讨论,提出了判断满足空化初生条件的标准     

应用遗传算法和神经网络预测粮食总产量

摘要:通过对我国二十个省市粮食总产量的调查,分析影响粮食总产量的主要因素（农业机械总动力,有效灌溉面积,化肥施用量,农业从业人员）建立GA-BP神经网络模型,获得粮食总产量数学模型。同时,对此模型进行检测。在模型处理的过程中,应用遗传算法优化BP神经网络模型权值和阈值,获得优化后的网络模型,经过比较得出GA-BP神经网络模型在速度和精度上都高于BP神经网络的粮食总产量预测模型。     

化学沉积法制备CdS纳米薄膜及成膜机理

分别以Cd(NO_{3)2和(NH2)2CS作为镉源和硫源, 用化学沉积法(CBD)在ITO玻璃上生长CdS半导体纳米薄膜. 考察了Cd^{２＋浓度、 沉积温度、 沉积时间和后处理温度对CdS成膜的影响. 紫外 可见吸收谱和原子力显微镜结果表明, 改变溶液浓度和后处理温度都能有效调节CdS的吸收带边, 得到均一致密的CdS纳米薄膜. 探讨了膜形成机理, 给出了成核过程模型, 进一步修正了传统成膜机制. 认为ITO玻璃基片表面活性位和晶核的形成是均一致密CdS纳米膜形成的关键. 晶核的形成是电学、 热学、 力学和化学等因素共同作用的结果.}}     

Dissection of the molecular mechanisms that control the nuclear accumulation of transport factors importin-α and CAS in stressed cells

The physiological state of eukaryotic cells controls nuclear trafficking of numerous cargos. For example, stress results in the inhibition of classical protein import, which is characterized by the redistribution of several transport factors. As such, importin-alpha and cellular apoptosis susceptibility protein (CAS) accumulate in nuclei of heat-shocked cells; however, the mechanisms underlying this relocation are not fully understood. We now show that heat upregulates the initial docking of importin-alpha at the nuclear envelope and stimulates the translocation of CAS into the nuclear interior. Moreover, heat exposure compromises the exit of importin-alpha from nuclei and drastically increases its retention in the nucleoplasm, whereas CAS nuclear exit and retention are less affected. Taken together, our results support the idea that heat shock regulates importin-alpha and CAS nuclear accumulation at several levels. The combination of different stress-induced changes leads to the nuclear concentration of both transport factors in heat-stressed cells.     

Influence of temperature on taste perception

Daily experience tells us that temperature has a strong influence on how we taste. Despite the longstanding interest of many specialists in this aspect of taste, we are only starting to understand the molecular mechanisms underlying the temperature dependence of different taste modalities. Recent research has led to the identification of some strong thermosensitive molecules in the taste transduction pathway. The cold activation of the epithelial Na⁺ channel and the heat activation of the taste variant of the vanilloid receptor (TRPV1t) may underlie the temperature dependence of salt responses. Heat activation of the transient receptor potential channel TRPM5 explains the enhancement of sweet taste perception by warm temperatures. Current development of methods to study taste cell physiology will help to determine the contribution of other temperature-sensitive events in the taste transduction pathways. Vice versa, the analysis of the thermodynamic properties of these events may assist to unveil the nature of several taste processes. Received 29 August 2006; received after revision 5 October 2006; accepted 20 November 2006     

Nibbling within the nucleus: turnover of nuclear contents

As the site of gene expression and regulation, the nucleus is the control center of the cell. It might be thought that degradation of nuclear contents is strictly ‘off-limits,’ given the importance of the genetic information contained within the nucleus, but it has recently been reported that partial degradation of the nucleus may occur in yeast. Here we summarize the evidence for the degradation and quality control of proteins found with the nucleus and its compartments, and of nucleic acids that may occur under certain specific conditions. Only under certain special conditions such as differentiation of the lens are the entire nuclear contents degraded. Received 6 September 2006; received after revision 25 October 2006; accepted 13 December 2006     

选择性神经电剌激方法的仿真研究

为了研究神经纤维的兴奋规律，建立了单根神经纤维在脉冲剌激下的兴奋规律仿真系统．并在此基础上，对３种常用的选择性剌激方法进行了探讨和比较．为了改善电化学损伤问题，给出了１种双向选择性剌激模式，并进行了有益的探索．