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21.
Induction of hemopoietic chimerism in the caprine fetus by intraperitoneal injection of fetal liver cells 总被引:1,自引:0,他引:1
R. D. Pearce D. Kiehm D. T. Armstrong P. B. Little J. W. Callahan L. R. Klunder J. T. R. Clarke 《Cellular and molecular life sciences : CMLS》1989,45(3):307-308
Summary Intraperitoneal injection of allogeneic liver cells from 43-day-old male fetuses into normal 60-day female goat fetuses resulted in persistent hemopoietic chimerism in surviving recipients without clinical evidence of graft-versus-host disease. Transplantation of normal fetal liver cells into preimmunocompetent goat fetuses affected with -D-mannosidosis may provide an alternative strategy for evaluating hemopoietic stem cell transplantation in the treatment of human lysosomal storage diseases. 相似文献
22.
J. P. J. Billen B. D. Jackson E. D. Morgan 《Cellular and molecular life sciences : CMLS》1988,44(9):794-797
Summary The principal constituent of the pygidial gland ofNothomyrmecia macrops is 3,7-dimethyloct-6-en-2-one, a substance not previously identified in insects. Also identified were 2,6-dimethylhept-5-enal, 2-nonanone, indole, -dodecalactone, and the hydrocarbons pentadecane, heptadecane, heptadecene and heptadecadiene, all in low nanogram quantities. 相似文献
23.
N. Akaike K. Hattori Y. Oomura D. O. Carpenter 《Cellular and molecular life sciences : CMLS》1985,41(1):70-71
Summary Using isolated, internally perfused bullfrog dorsal root ganglion cells we have studied the dose-response curves for -aminobutyric acid (GABA) in the presence of internally or externally applied GABA antagonists. With external application of antagonists the inhibition of the GABA current by bicuculline was competitive and that by picrotoxin was noncompetitive. Picrotoxin but not bicuculline blocked when internally perfused.To whom reprint requests should be addressed.Acknowledgments. We thank Drs S. Minakami and S. Yasui for helpful discussions and comments. 相似文献
24.
25.
S. J. Arnold 《Cellular and molecular life sciences : CMLS》1985,41(10):1296-1310
Summary Quantitative genetic models of sexual selection have disporven some of the central tenets of both the handicap mechanism and the sexy son hypothesis. These results suggest that the good genes approach to sexual selection may generally lead to erroneous results.Runaway sexual selection seems possible under a wide variety of circumstances. Quantittive genetic models have revealed runaway processes for sexually selected attributes expressed in both sexes and for attributes of parental care. Furthermore, the runaway could occur simultaneously in a series of populations that straddle an environmental gradient. While the models support the feasibility of runaway processes, empirical studies are needed to evaluate whether runaways actually happen. Estimates of critical genetic parameters are particularly needed, as well as measures of natural and sexual selection acting on the same population.The models also show that sexual selection has tremendous potential to produce population differentiation, particularly in epigamic traits. Differentiation is promoted by indeterminancy of evolutionary outcome, transient differences among populations during the final slow approach to equilibrium, sampling drift among equilibrium populations, and the tendency of sexual selection to amplify geographic variation arising from spatial differences in natural selection. Recent work with two- and three-locus models of sexual selection has produced results that parallel the results of the polygenic models36–38,58. Thus the feature of indeterminate equilibria (outcome dependent on initial conditions) is common to both types of model. 相似文献
26.
S. Burstein S. A. Hunter V. Latham L. Renzulli 《Cellular and molecular life sciences : CMLS》1987,43(4):402-403
Summary The results described here demonstrate that THC-induced catalepsy in mice can be substantially inhibited by the prior administration of 1-THC-7-oic acid, the major metabolite of THC in most species including humans. This raises the possibility that the intensity and duration of action of THC may depend to a large degree on the levels of this metabolite at the sites of action.We thank the National Institute on Drug Abuse for supporting this project by grants DA-02043 and DA-02052 and for supplying all of the cannabinoids. One of us (S.B.) is also the recipient of a Research Scientist Award from NIDA. We are grateful to Kristen Carlson and Thomas Honeyman for helpful suggestions in preparing this report. 相似文献
27.
设计了一种新型的双通道动态无线充电系统耦合机构,以解决动态无线充电系统在分段式发射导轨切换处的功率跌落问题。通过LCC-LCC型补偿拓扑,设计了两路能量传输通道,利用LCC-LCC补偿拓扑的恒流特性,推导了系统输出以及损耗与两通道耦合参数之间的关系,实现了较为稳定的功率传输,提升了系统的抗偏移特性以及抗跌落能力。最后对所提方法进行了仿真和实验,验证了双通道动态无线电能传输方案的可行性。 相似文献
28.
用五种Schif碱型双(苯并_15_冠_5)为离子载体,在水_1,2_二氯乙烷体系中研究了其对碱金属苦味酸盐的萃取性能,测定了分配比D和萃取平衡常数Ke.结果表明,这些双冠醚与苦味酸钠以1∶1(冠醚单元∶金属离子)形式络合,而与苦味酸钾和苦味酸铷则以2∶1形式络合. 相似文献
29.
SrGa2S4: Ce blue TFEL device with a novel structure was prepared by electron beam evaporation. The dielectric constant of insulator
layer in this structure is far less than that in the conventional structure, so the hot-electrons can be accelerated in SiO2 layers. The stable TFEL with good chromaticity was achieved and the basic characteristics were investigated. 相似文献
30.
冯长君 《徐州师范大学学报(自然科学版)》1998,(3)
Lewis酸的电负性(xL)和原子势(Z/rc)是影响Lewis酸硬软度(FA)的主要因素,本文给出了它们之间的数学关系式.根据FA值大小,把Lewis酸分成三类,这与Pearson分类基本一致.用最小二乘法成功地建立FA与配合物的lgKf的线性回归方程,均通过F检验. 相似文献