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82.
83.
HE Hongjun CAO Sihua LUO Li FENG Tao PAN Li ZOU Zhiji 《武汉大学学报:自然科学英文版》2006,11(6):1697-1700
Security experts have not formally defined the distinction between viruses and normal programs. The paper takes user's intension as the criteria for malice, gives a formal definition of viruses that aim at stealing or destroying files, and proposes an algorithm to detect virus correctly. Compared with traditional definitions, this new definition is easy to understand, covers more malwares, adapts development of virus technology, and defines virus on the spot. The paper has also analyzed more than 250 real viruses and finds that they are all in the domain of the new definition, this implies that the new definition has great practical significance. 相似文献
84.
LIUGuangqing LIUZaixin XIEQingge CHENYingli BAOHuifang LIUXiangtao 《科学通报(英文版)》2004,49(11):1137-1141
The China foot-and-mouth virus (FMDV) isolate OH/CHA/99 was isolated from swine, which was unable to infect bovine thyroid cells in vitro or to cause typical disease in bovines following intradermal inoculation in the tongue. To enhance antigenicity, replication, maturation and pathogenicity studies of OH/CHA/99, an infectious fulllength cDNA clone, designated pBIFMDV, was prepared. The in vitro and in vivo biological properties of the virus derived from pBIFMDV were studied by analyzing antigenicity, plaque morphology and virulence in pigs. The results showed that the virus derived from pBIFMDV had the same biological properties as the parent strain OH/CHA/99; the fulllength infections cDNA clone, pBIFMDV, will be very useful in studies of the antigenicity, virulence, pathogenesis, maturation and replication of FMDV. 相似文献
85.
Immunogenicity of recombinant fowl-pox virus co-expressing structural protein precursor P1-2A and proteinase 3C of FMDV 总被引:1,自引:0,他引:1
JINNingyi ZHANGHongyong YINGefeng ZHENGMin LIUTong JIANGWenzheng LIZijian 《科学通报(英文版)》2004,49(8):823-823
Two recombinant plasmids, pUTA2P1 and pUTAL3CP1, were constructed by inserting structural protein precursor P1-2A and proteinase 3C of foot-and-mouth disease virus (FMDV) into fowl-pox virus (FPV) recombinant vectors pUTA-2 and pUTA-16-LacZ respectively, and two recombinant FPVs (vUTA2P1 and vUTAL3CP1) screened by the RT-PCR, IFA assay and Western blotting assay were obtained successfully. Mice injected respectively with rFPVs were induced high level specific anti-FMDV antibodies, increasing of T subtypes, and higher cytotoxicities of splenocytes than those of control groups. These results indicated that a new method was used to construct a potential candidate vaccine of FMDV. 相似文献
86.
CUIXiaofeng ZHOUXueping 《科学通报(英文版)》2004,49(24):2607-2612
Tomato yellow leaf curl China virus Y10 isolate (TYLCCNV-Y10) alone could systemically infect host plants such as Nicotiana benthamiana without symptoms. In contrast, Tobacco curly shoot virus Y35 isolate (TbCSV-Y35) alone induces leaf curl symptoms in N. benthamiana. When inoculated into transgenic N. benthamiana plants expressing GFP gene (line 16c), TYLCCNV-Y10 neither reverses the established GFP silencing nor blocks the onset of GFP silencing. In contrast, TbCSV-Y35 can partially reverse the established GFP silencing and block the onset of GFP silencing in new leaves. In the patch co-infiltration assays, the AC2 and AC4 proteins of TYLCCNV-Y10 and TbCSV-Y35 could suppress local GFP silencing and delay systemic GFP silencing, suggesting that they are suppressors of RNA silencing. Comparison of the accumulation levels of GFP mRNA in the co-infiltration patches showed that Y10 AC2 and Y35 AC2 proteins had similar efficiency for suppression of RNA silencing. However, Y35 AC4 protein functioned as a stronger suppressor of RNA silencing than Y10 AC4 protein. There-fore, the pathogenicity difference between TbCSV-Y35 and TYLCCNV-Y10 may be related to the functional difference in their AC4 proteins. 相似文献
87.
徐秋菊 《科技情报开发与经济》2003,13(12):210-211
对传统型计算机病毒与新型计算机病毒的特点、传播途径等进行了总结和比较,重点介绍了3种最新的计算机病毒的特征及其危害性,它们分别是“苏珊”病毒、“笑脸”病毒和“9·11”计算机病毒。 相似文献
88.
董建慧 《科技情报开发与经济》2007,17(36):212-213
介绍了搞好校园网络安全的主要措施,包括加强网络监控、注意密码的安全、及时修补漏洞、设置共享时一定要设定访问密码等。 相似文献
89.
The effect of carboxymethytl pachymaram (CMP) on the function of dendritic cells(DCs) derived from spleens of hepatitis B
virus transgenic mice are studied in vitro. The phenotypes of DCs are tested by flow cytometry (FCM), cytokines measured by ELISA. The expression of DCs’ phenotypes
in HBV transgenic mice are low (CD80+CD11c+:59.12±11.53 vs 9.60±4.53, p<0.01; CD80+ MHC-II+: 44.86±12.31 vs 9.80±5.72, p<0.01, normal mice vs HBV transgenic mice), the ability of DCs stimulating T lymphocytes proliferation decreases (0.37±0.11 vs 0.20±0.11, p<0.05, normal mice vs HBV transgenic mice), levels of IL-12 and IFN-γ decrease whereas the level of IL-10 increases; CMP can enhance DCs’ ability of stimulating T lymphocytes proliferation, facilitate
the secretion of IL-12 and IFN-γ, inhibit the secretion of IL-10, thus up regulates DCs function. The results show a good prospective use of CMP on the treatment
of chronic hepatitis B.
Biography: HOU Anji (1963–), male, Ph.D. candidate, Associate professor, research direction: clinical virology. 相似文献
90.
王亚冰 《科技情报开发与经济》2007,17(32):212-214
介绍了计算机病毒的概念与机理,分析了蠕虫病毒和特洛伊木马,提出了处理病毒及其威胁的办法,总结了一些安全措施。 相似文献