转基因动物的研究现状及展望

介绍了转基因鼠、转基因猪、转基因鱼、转基因牛的研究现状和产生的效益,展望了转基因动物的发展前景,并对其未来发展提出了建议。     

Identify Implicit Communities by Grap Clustering

How to find these communities is an important research work. Recently, community discovery are mainly categorized to HITS algorithm, bipartite cores algorithm and maximum flow/minimum cut framework. In this paper, we proposed a new method to extract communities. The MCL algorithm, which is short for the Markov Cluster Algorithm, a fast and scalable unsupervised cluster algorithm is used to extract communities. By putting mirror deleting procedure behind graph clustering, we decrease comparing cost considerably. After MCL and mirror deletion, we use community member select algorithm to produce the sets of community candidates. The experiment and results show the new method works effectively and properly.     

Genetic analysis and molecular mapping of a presenescing leaf gene psll in rice （Oryza sativa L.）

A rice psl1 （presenescing leaf） mutant was obtained from a japonica variety Zhonghua 11 via radiation of ^60Co-γ in M2 generation. Every leaf of the mutant began to wither after it reached the biggest length, while the leaves of the wild variety could keep green for 25--35 d. In this study, genetic analysis and gene mapping were carried out for the mutant identified. The SSR marker analysis showed that the mutant was controlled by a single recessive gene （psl1） located on chromosome 2. Fine mapping of the psl1 locus was conducted with 34 new STS markers developed around psl1 anchored region based on the sequence diversity between Nipponbare and 93-11. The psl1 was further mapped between two STS markers, STS2-19 and STS2-26, with genetic distances of 0.43 and 0.11 cM, respectively, while cosegregated with STS2-25. A BAC contig was found to span the psl1 locus, the region being delimited to 48 kb. This result was very useful for cloning of the psl1 gene.     

一类基于二部图的（g，f）-2-覆盖图的研究

一个图G称（g,f）-2-覆盖图，如G的任何两条边都属于它的一个（g,f）-因子．本文得到了如下结论：（i）当g≤f时一个二部图是（g,f）-2-覆盖图的一个充分必要条件；（ii）当f（x）=f（Y）时一个二部图是f-2-覆盖图的一个充分必要条件．     

分子伴侣及其作用机理的研究概况

分子伴侣为一类与其他蛋白不稳定构象结合并使之稳定的蛋白质,广泛分布于各种生物体内。本文对分子伴侣的最新研究作一综述。     

泛圈图的一个充分条件

在文[1]中给出定理,设G是一个n-阶2-连通图且δ（G）≥t,若对于G的任意两个不相邻的点u和v,均有｜N（u）∪N（v）｜≥n-t成立,则G是一个泛圈图或G≌Kn/2,n/2.本文的目的在于将此定理的条件减弱,只对图中距离为2的点进行讨论,得出了泛圈图的一个充分条件.文中主要用数学归纳法对定理进行证明,先在引理中给出了几种特殊情况的证明,接着在定理的证明中讨论了一般情形.     

分子印迹技术研究的新进展

分子印迹技术是制备对特定分子具有特异性识别能力的高分子聚合物的一种技术,本文就近些年来分子印迹技术在合成单体、合成方法以及应用领域等方面取得的新进展进行了综述.     

水生动物细胞周期蛋白研究进展

细胞周期蛋白是真核细胞周期循环中主要的调控因子，参与细胞周期的精密调控，维持细胞正常生长及发育平衡．本文简述了细胞周期蛋白与水生动物卵子发生、早期胚胎发育的关系以及细胞周期蛋白在生殖过程的表达与调控．     

牡蛎低分子活性肽对人肺腺癌A549细胞形态与超微结构变化的影响

以牡蛎（Saccostrea cucullata）体内分离提取出的牡蛎天然低分子活性多肽（BPO-L，Bioactive Peptides of Oyster in Peak L）为效应物，观察研究BPO-L对人肺腺癌细胞形态和超微结构的影响．光镜观察显示经0．1mg／mL BPO-L处理后的A549细胞体积增大，趋于扁平铺展状态，细胞核质比例变小，核仁数量减少．透射电镜观察显示经0．1mg／mL BPO-L处理后的A549细胞核形态较规则，细胞核内异染色质减少，常染色质增多；细胞质内线粒体数量增多，结构较为一致，高尔基体呈较为典型发达状态，并出现粗面内质网增多和多聚核糖体减少等变化．结果表明，BPO-L能有效改变人肺腺癌细胞的恶性形态与超微结构特征，对肺癌细胞具有一定的诱导分化作用．     

含隐变量和选择偏差的图模型中的因果推断

Bayes网络常用于多变量间的因果推断,但当存在未观测的隐变量和选择变量时,这种图模型往往无法正确描述观测变量间的因果关系。作者利用在观测变量上构造的最大祖先图模型刻画观测变量间的独立性关系和因果结构,并提出了具体的实现算法,从而可由观测数据来推断这类不完全观测下的部分因果关系。