基于蒙特卡洛仿真的液压系统动态可靠性

由于传统可靠性分析方法侧重于系统静态结构的描述,难以反映系统的动态运行过程,所以采用蒙特卡洛仿真方法研究液压系统的动态可靠性特征,重点计算液压元件故障服从不同分布、元件维修后故障率服从不同分布条件下液压系统可靠性指标的变化.仿真结果表明:修复如新时,不同分布对系统动态可靠性指标影响较小;修复如旧时,不同分布对系统动态可靠性指标影响较大.以可靠性仿真数据为基础,给出液压系统预防性维修策略.     

曲线的主法线曲面

在三维欧氏空间中,作为特殊曲线,Mannheim曲线、Bertrand曲线以及一般螺线具有良好的几何和代数性质.讨论了三维欧氏空间中特殊曲线的主法线曲面.根据渐近曲线的方程,具体给出主法线曲面的一族非直线的渐近曲线.再根据平均曲率、高斯曲率及主曲率函数,能得到曲线的主法线曲面的极小轨迹、常高斯曲率曲线及两个主曲率函数之比为常数的曲线.还给出曲面上测地线和腰曲线的性质.     

一类特殊的有限p-群

探讨了一类特殊的有限p -群,即对任意x,y∈G,如果[x,y]≠1,那么《x,y》(△)-G.主要证明了:如果满足这样条件的有限p -群G＝《x1,x2,…,xn》,其中对任意x∈G,《x》G是交换群或者内交换群.     

Histone methylation and ubiquitination with their cross-talk and roles in gene expression and stability

Methylation of lysine residues of histones is associated with functionally distinct regions of chromatin, and, therefore, is an important epigenetic mark. Over the past few years, several enzymes that catalyze this covalent modification on different lysine residues of histones have been discovered. Intriguingly, histone lysine methylation has also been shown to be cross-regulated by histone ubiquitination or the enzymes that catalyze this modification. These covalent modifications and their cross-talks play important roles in regulation of gene expression, heterochromatin formation, genome stability, and cancer. Thus, there has been a very rapid progress within past several years towards elucidating the molecular basis of histone lysine methylation and ubiquitination, and their aberrations in human diseases. Here, we discuss these covalent modifications with their cross-regulation and roles in controlling gene expression and stability. Received 24 September 2008; received after revision 21 November 2008; accepted 28 November 2008     

半马氏市道轮换利率期限结构模型——基于最小Tsallis熵鞅测度

基于Ho-Lee模型,讨论零息债券价格的演变,应用无套利原理和鞅测度的方法,建立了一个离散时间半马氏过程控制的市道轮换下的二叉树期限结构模型.运用最小Tsallis熵鞅测度(the minimal Tsallis entropy martingale measure,MTEMM)处理上述模型,并在马氏和半马氏市道下给出在欧式债券期权定价方面的应用.研究发现模型结果与最小熵鞅测度下的结果具有一致性.     

微分方程的反序上下解方法

利用反序上下解组合单调迭代技术,讨论了一类带积分边界条件的微分方程解的存在性问题,得到了几个新的存在性定理.     

虚拟手术中基于最少单元分裂的切割仿真技术

详细论述了虚拟手术中切割仿真技术的实现.虚拟软组织模型由四面体网格构成,四面体分裂算法使用了最少单元分裂法.为了提高算法效率,设计了由顶点、边、面和四面体4种基本单元构成,并且具有相关指针的软组织模型数据结构.详细阐述了最少单元分裂法中每种分裂类型的具体实现,以及解决内部分裂不一致问题的方法.碰撞检测使用了基于空间一致性原则的邻域搜索法.最后给出了使用肝脏模型进行切割仿真的结果.     

Retail default prediction by using sequential minimal optimization technique

This paper employed sequential minimal optimization (SMO) to develop default prediction model in the US retail market. Principal components analysis is used for variable reduction purposes. Four standard credit scoring techniques—naïve Bayes, logistic regression, recursive partitioning and artificial neural network—are compared to SMO, using a sample of 195 healthy firms and 51 distressed firms over five time periods between 1994 and 2002. The five techniques perform well in predicting default particularly one year before financial distress. Furthermore, the prediction still remains sound even 5 years before default. No single methodology has the absolute best classification ability, as the model performance varies in terms of different time periods and variable groups. External influences have greater impacts on the naïve Bayes than other techniques. In terms of similarity with Moody's ranking, SMO excelled over other techniques in most of the time periods. Copyright © 2008 John Wiley & Sons, Ltd.     

曲马多超前镇痛用于小儿腭裂修补术的临床观察

目的观察小儿腭裂修补术中曲马多超前镇痛的有效性和安全性。方法选择46例美国麻醉医师协会分级法（ASA）Ⅰ—Ⅱ级腭裂修补术患儿，年龄1～3岁，随机分为曲马多组和对照组，全麻诱导气管插管后在术前分别静推曲马多2mg/kg和相同容量的生理盐水。记录患儿围麻醉期间血流动力学变化，并测定苏醒期的躁动评分，观察有无恶心呕吐、呼吸抑制、反流误吸等不良反应。结果两组患儿围麻醉期间术中血流动力学平稳，组间差异无显著性；但曲马多组在拔管时和苏醒期血流动力学明显较对照组平稳。苏醒期躁动评分曲马多组满意率明显高于对照组（P〈0．05）。两组患儿均未发生恶心呕吐、呼吸抑制、反流误吸等不良反应。结论小儿腭裂修补术术前静推曲马多2mg/kg可获得围麻醉期间较为平稳的血流动力学，减少拔管期的躁动，且不增加术后呼吸抑制、恶心呕吐等不良反应的发生率。