黄连素的十大药理功能

本文通过查阅大量文献,综合分析近年来关于黄连素药理作用研究情况,总结出黄连素十大药理功能,旨在理顺有关黄连素的研究思路,为更加合理的研究开发和使用黄连素提供理论支持。     

Effects of atmospheric pollution on human health

Most air pollutants do not lead to specific diseases. Depending on the pollutant, the concentration and the duration of exposure, some organs are more affected than others. The most frequent disorders are those caused by irritant gases and particulates on the mucous membranes and respiratory organs. The consequences are eye, nose and throat inflammations, diminished lung function, increased susceptability to respiratory infection and a higher incidence of chronic bronchitis. These disorders and diseases are, of course, influenced by other factors as well, such as immune deficiency, allergies, occupational exposure to pollutants, and particularly smoking. The effects of air pollutants are, therefore, multifactorially conditioned and nonspecific disorders are placed in the foreground. Evidence for an association of air pollution with adverse effects on human health is drawn from three sources: animal experiments, experimental human exposures, and epidemiologic studies of exposed human populations. The burden of atmospheric pollution must be reduced to protect human health by an adequate safety margin. In particular, the increased sensitivity of sick and aged people as well as children should be taken into account. In defining the maximum emmission levels, preventive aspects should have priority so as to keep the risk of damage to health and the harmful influences on the environment to a minimum.This article Effects of atmospheric pollution on human health by H. U. Wanner is a revised version of the same article that was first published in the Proceedings of the 1990 European Aerosol Conference; special issue of the J. Aerosol Sci., Vol. 21, Suppl. 1 (1990) 389–396.Reprinted with kind permission from Pergamon Press Ltd, Headington Hill Hall, Oxford OX3 0BW, Great Britain.     

中国股市交易量的周内效应

研究了中国股市交易量在一周里面的变化规律,采样时间跨度是从1990-12-19到2002-12-31。以市场换手率度量交易量,采用自回归广义自回归条件异方差(AR-GARCH)模型研究了中国股市交易量的时间系列。研究结果显示沪市和深市的日市场换手率不服从正态分布并且存在着自相关性和ARCH效应;AR-GARCH模型很好地拟合了日市场换手率时间系列,估计出来的参数十分显著;周一到周五的日市场换手率存在显著差异并且周一的市场换手率达到了一周的最大值。利用混合分布假说进行了解释,非交易日的信息积累可能是周一高换手率的原因。结果指出:在该研究的样本范围内,中国股市交易量存在着周内效应。     

Fe-13Cr-5Ni马氏体不锈钢在连续加热过程中两相区的奥氏体生长行为

通过光学显微镜、透射电子显微镜、X射线衍射仪以及显微硬度仪研究Fe-13Cr-5Ni马氏体不锈钢在加热过程中的组织转变行为.结果表明,Fe-13Cr-5Ni钢在10℃·s-1的加热速率下,加热至奥氏体单相区,冷却至室温后具有明显的“组织遗传”现象.奥氏体以“针状”形式在马氏体板条界处形核并沿着马氏体板条界长大,与母相间保持Kurdjumov-Sachs(K-S)位向关系.加热至两相区不同温度然后淬火至室温,奥氏体的量随两相区保温温度的升高先增加再减少,650℃时对应室温下残余奥氏体的极大值,并且这一变化趋势与试样显微硬度测试结果所得结论一致.     

Volterra series based predistortion for broadband RF power amplifiers with memory effects

RF power amplifiers(PAs)are usually considered as memoryless devices in most existing predistortion techniques.However,in broadband communication systems,such as WCDMA,the PA memory effects are significant,and memoryless predistortion cannot linearize the PAs effectively.After analyzing the PA memory effects,a novel predistortion method based on the simplified Volterra series is proposed to linearize broadband RF PAs with memory effects.The indirect learning architecture is adopted to design the predistortion scheme and the recursive least squares algorithm with forgetting factor is applied to identify the parameters of the predistorter.Simulation results show that the proposed predistortion method can compensate the nonlinear distortion and memory effects of broadband RF PAs effectively.     

A STAGE-STRUCTURED SI ECO-EPIDEMIOLOGICAL MODEL WITH TIME DELAY AND IMPULSIVE CONTROLLING*

This paper formulates a robust stage-structured SI eco-epidemiological model with periodic constant pulse releasing of infectious pests with pathogens. The authors show that the conditions for global attractivity of the ＇pest-eradication＇ periodic solution and permanence of the system depend on time delay, hence, the authors call it ＂profitless＂. Further, the authors present a pest management strategy in which the pest population is kept under the economic threshold level （ETL） when the pest population is uniformly persistent. By numerical analysis, the authors also show that constant maturation time delay for the susceptible pests and pulse releasing of the infectious pests can bring obvious effects on the dynamics of system.     

基于位置和散度效应因子分类筛选及仿真试验

针对供应链及其它计算机仿真试验中所涉及因子数目众多的情形,序贯分支方法因筛选效率较高被广泛采用.然而,现有的序贯分支方法忽视对散度效应起显著作用的因子.由于相比位置效应,散度效应在产品或供应链系统的质量设计中是同等甚至更为重要的,故提出一种基于位置效应与散度效应的序贯分支方法.首先,将影响位置效应与散度效应的显著因子分类为调节因子,重要因子和稳健因子;然后,结合序贯概率比检验(sequential probability ratio test,SPRT),在控制筛选过程中第一类错误和第二类错误的基础上,采用序贯分支方法分类地筛选出显著因子;最后通过仿真试验说明此方法能够有效且分类地处理位置效应与散度效应下的显著因子筛选问题.     

逃离“北上广深”背景下一线城市房价涟漪效应研究

本文基于逃离"北上广深"背景,研究了一线城市对二三线城市的房价涟漪效应,并从城市规模大小、距一线城市远近和涟漪效应高低三个方面,对比分析各因素对涟漪效应的影响.研究发现:1)逃离"北上广深"背景下,产业相似度、生活舒适性差距、交通便捷性、住房市场信息距离、社会文化距离、就业增长率、开放度和总储蓄均对涟漪效应表现出显著促进作用;2)二线城市各因素的影响程度均大于三线城市;3)随着与一线城市距离的增加,产业相似度、交通便捷性、就业增长率和开放度的影响呈递减趋势,生活舒适性差距呈递增趋势,住房市场信息距离和总储蓄基本与距离无关;4)随分位数提高,多数变量的影响程度增强,表现出"加速效应".     

A new cascading failure model with delay time in congested complex networks

Cascading failures often occur in congested complex networks. Cascading failures can be expressed as a three-phase process: generation, diffusion, and dissipation of congestion. Different from the betweenness centrality, a congestion function is proposed to represent the extent of congestion on a given node. Inspired by the restart process of a node, we introduce the concept of “delay time,” during which the overloaded node cannot receive or forward any traffic, so an intergradation between permanent removal and nonremoval is built and the flexibility of the presented model is demonstrated. Considering the connectivity of a network before and after cascading failures is not cracked because the overloaded node are not removed from network permanently in our model, a new evaluation function of network efficiency is also proposed to measure the damage caused by cascading failures. Finally, we investigate the effects of network structure and size, delay time, processing ability, and traffic generation speed on congestion propagation. Cascading processes composed of three phases and some factors affecting cascade propagation are uncovered as well.