某大跨度变截面连续箱梁桥承载能力的评价

基于通用有限元程序软件ANSYS对某大桥进行了有限元分析,并把理论分析计算结果与实测结果进行比较分析,从中对该桥静动载的性能进行评价。     

新光大桥的动力特性和地震行波效应研究

新光大桥位于广州新光快速路主干线,是世界上第一座三跨连续钢桁拱与钢筋混凝土V型刚构结合的钢-混凝土组合体系桥梁,主桥跨度为177 428 177 m,在目前同类型桥梁中,主桥长度位居世界第一.该桥结构新颖,造型独特.文章主要针对新光大桥的动力特性和地震行波效应进行了详细研究.在两水准、两阶段抗震设防思想下给出了主要控制构件在考虑行波效应情况下的内力,并与纵桥向地震一致激励作用下的内力进行了比较;同时给出了在不同剪切波速下,主拱顶截面的位移时程曲线.研究表明行波效应以及地面剪切波速度对大跨度连续刚架钢桁拱桥的地震响应有着较大的影响.     

基于ANSYS的大跨度斜拉桥非线性成桥索力优化研究

将有限元计算与优化设计分析相结合,在索力变化对结构响应和目标函数敏感性分析的基础上,综合考虑结构内力、线形控制条件,提出一种全过程计入结构几何非线性影响的大跨斜拉桥合理成桥索力优化方法,采用一阶分析法对成桥索力进行迭代优化.基于ANSYS的优化分析模块,对一大跨斜拉桥成桥索力进行了计算,验证了方法的正确性和有效性.     

体育馆屋盖的风洞试验研究和数值计算

对一系列不同倾角的体育馆悬挑屋盖进行了风洞试验;模型比例为1:50,在屋盖上下表面安装128对测压管,在同步测压的基础上,我们获得每个测点的风压时程,通过对试验数据的处理,分析平均风压和脉动风压的产生机理.试验表面明,风压分布是受屋盖表面的气流流动分离所影响的.同时,对这种形式屋盖进行计算分析.     

装配式混凝土板桥桥面加固技术的试验研究

通过在装配式混凝土板板顶植筋并对桥面施加横向预应力,不但可以加强板与桥面铺装层的连接,而且还可以加强整体结构的横向整体性,增强结构对动载冲击、震动、磨耗抵抗能力.以寨河桥为工程实例,进行了植筋和预应力张拉前后10个工况的混凝土板挠度和应力的现场测试,结果表明,植筋等增加桥面预应力的措施确实能够预防桥面病害的发生,并能提高桥面的承载力,减小挠度,为相关工程提供了依据.     

荷载横向分布计算方法比较分析

荷载横向分布系数是桥梁设计计算的首要任务,关系到结构的安全性和可靠性.通过对一座标准T梁桥的荷载横向分布影响线进行计算,并与试验结果对比,分析了几种横向分布计算方法的区别与联系,总结了各方法的优缺点与适用性.     

Telomeres and meiosis in health and disease

Telomeres are important segments of chromosomes that protect chromosome ends from nucleolytic degradation and fusion. At meiosis telomeres display an unprecedented behavior which involves their attachment and motility along the nuclear envelope. The movements become restricted to a limited nuclear sector during the so-called bouquet stage, which is widely conserved among species. Recent observations suggest that telomere clustering involves actin and/or microtubules, and is altered in the presence of impaired recombinogenic and chromosome related functions. This review aims to provide an overview of what is currently known about meiotic telomere attachment, dynamics and regulation in synaptic meiosis.     

The cold case: Are rhinoviruses perfectly adapted pathogens?

Rhinoviruses, which cause common cold, belong to the Picornaviridae family, small non-enveloped viruses (diameter 15-30 nm) containing a single-stranded RNA genome (about 7 kb). Over 100 different rhinoviral serotypes have been identified thus far, establishing rhinoviruses as the most diverse group of Picornaviridae. Based on receptor binding properties, rhinoviruses are divided into two classes: the major group binding to intracellular adhesion molecule-1 and the minor group binding to the very low density lipoprotein receptors. Interactions between virus and the receptor molecules cause a conformational change in the capsid, which is a prerequisite for viral uptake. Rhinoviruses trigger a chemokine response upon infection that may lead to exacerbation of the symptoms of common cold, i.e. asthma and inflammation. The following review aims to summarize the knowledge about rhinoviral infections and discusses therapeutical approaches against this almost perfectly adapted pathogen.