Myelin basic protein: a multifunctional protein

Myelin basic protein (MBP), the second most abundant protein in central nervous system myelin, is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin. A member of the ‘intrinsically disordered’ or conformationally adaptable protein family, it also appears to have several other functions. It can interact with a number of polyanionic proteins including actin, tubulin, Ca²⁺-calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. Some size isoforms of MBP are transported into the nucleus and thus they may also bind polynucleotides. Extracellular signals received by myelin or cultured oligodendrocytes cause changes in phosphorylation of MBP, suggesting that MBP is also involved in signaling. Further study of this very abundant protein will reveal how it is utilized by the oligodendrocyte and myelin for different purposes. Received 2 March 2006; received after revision 12 April 2006; accepted 16 May 2006     

利用JPEG压缩特性的合成图像检测

提出一种利用压缩特性进行JPEG合成图像检测的方案。由多幅JPEG图像内容拼接而成的合成图像中往往存在质量因子不一致性或分块位置不一致性,这两种不一致性可以作为检测JPEG合成图像的有力证据。该文所提方案先对待检测图像进行尝试性的再压缩并考察失真程度,以估计主要内容曾经历过的压缩情况,然后根据再压缩在不同区域引起的失真程度的起伏变化识别合成图像。该方法还可区分合成图像内容的不同来源,并分析质量因子不一致性或分块位置不一致性,为揭示图像伪造行为提供辅助信息。     

8周健身运动处方教学对保健班学生身体成分的影响

为了解健身运动处方对保健班学生身体成分的影响,对齐齐哈尔大学23名保健班学生进行8周健身运动处方教学,并对所有学生在8周教学前后的体脂百分比、BMI和身体形态等指标进行测试.结果表明,保健班学生实验后的体脂百分比出现一定程度的下降,符合健康标准的人数逐步增多,胸围和呼吸差发生了一定的变化(P<0.05),腰围在低于风险...     

Coordination-theoretic approach to modelling grid service composition process

A grid service composite process is made up of complex coordinative activities. Developing the appropriate model of grid service coordinative activities is an important foundation for the grid service composition. According to the coordination theory, this paper elaborates the process of the grid service composition by using UML 2.0, and proposes an approach to modelling the grid service composition process based on the coordination theory. This approach helps not only to analyze accurately the task activities and relevant dependencies among task activities, but also to facilitate the adaptability of the grid service orchestration to further realize the connectivity, timeliness, appropriateness and expansibility of the grid service composition.     

The carbon isotopic compositions of Non-methane Hydrocarbons in atmosphere

Carbon isotopic compositions of atmospheric Non-methane Hydrocarbons(NMHCs) in the urban areas of Taiyuan and Lanzhou in summer were reported and the sources of NMHCs are discussed.Carbon isotopic ratios(δ 13C) of vehicle exhaust,coal-combustion exhaust,fuel volatiles and cooking exhaust were also measured with thermal desorption-gas chromatography-isotope ratio-mass spectrometry(TD-GC-IR-MS).δ 13C values of NMHCs in the urban areas of Lanzhou and Taiyuan range from-32.3‰ to-22.3‰ and from-32.8‰ to-18.1‰.δ ...     

Evidence for the intracellular accumulation of anandamide in adiposomes

Anandamide is a lipid messenger that carries out a wide variety of biological functions. It has been suggested that anandamide accumulation involves binding to a saturable cellular component. To identify the structure(s) involved in this process, we analyzed the intracellular distribution of both biotinylated and radiolabeled anandamide, providing direct evidence that lipid droplets, also known as adiposomes, constitute a dynamic reservoir for the sequestration of anandamide. In addition, confocal microscopy and biochemical studies revealed that the anandamide-hydrolase is also spatially associated with lipid droplets, and that cells with a larger adiposome compartment have an enhanced catabolism of anandamide. Overall, these findings suggest that adiposomes may have a critical role in accumulating anandamide, possibly by connecting plasma membrane to internal organelles along the metabolic route of this endocannabinoid. S. Oddi, F. Fezza: These authors contributed equally to the study.     

片断化对常绿阔叶林种类组成的影响

森林片断化可能对植物群落带来不利的影响，该文调查片断化、半岛型和连续常绿阔叶林的五种丰富度和物种组成来衡量片断化的影向。片段化林地比相同面积的连续森林有更高的物种丰富度，物种丰富度最低的是半岛型样地。片断化林地和半岛型林地含有较多的外来种。结果表明，片断大小一物种丰富度有关，同时周围生态系统类型、经历片断化时间也影向物种丰富度和组成。干扰程度较高的半岛型林地中藤本植物很少，反映了林地质量较差，表明藤本植物可能可以作为我国东部人类干扰地区常绿阔叶林保护和管理的指示种。     

致密油储层CO2驱核磁共振实验研究

针对致密油储层动用困难问题本研究以CO_2为注入介质,对致密油注气开发效果进行评价,并借助核磁共振技术,从微观角度阐述了致密油储层注CO_2的驱替特征。实验结果表明,CO_2驱可以有效启动赋存在致密孔隙中的原油,非混相压力下(10 MPa),CO_2突破快,小孔隙中原油未动用,驱替后原油饱和度分布不均匀,驱替效率低;而在混相压力之上(24 MPa),CO_2突破明显变慢,驱替后原油饱和度均匀下降,大小孔隙中的原油均被启动,采出程度较高。此外从采出原油组成可以看出,高压下CO_2抽提作用非常明显,原油组分以C7~C29为主,几乎不合C30+组分,这表明CO_2会导致原油中重质组分在孔隙中沉积。     

珊瑚姜化学成分及精油研究开发进展

珊瑚姜是少数民族的一种民间习用药物,具有很大的潜在药用价值,对2003年以来珊瑚姜化学成分及精油的研究与开发进展进行了综述,指出深入研究珊瑚姜的非挥发油化学组分,寻找其有用的活性物质,开辟新的药用价值是其今后的研究方向。     

人和动物的多瘤病毒

多瘤病毒分类于乳多空病毒科，ＤＮＡ肿瘤病毒。病毒无囊膜，直径４０ｎｍ～４５ｎｍ，有３种～４种衣壳蛋白，基因组为约５０００对核苷酸组成的双链闭合环状ＤＮＡ。病毒在自然界分布广泛，目前已从人、兔子、小牛、鸟类、啮齿类和灵长类等动物分离到多种多瘤病毒。各病毒内部有共同的属特异性抗原，但大多数病毒表面蛋白无血清学交叉反应。病毒在容许细胞中增殖良好，能使非容许细胞发生转化，在转化细胞中病毒ＤＮＡ以整合到宿主染色体的方式存在。多瘤病毒感染有严格的种特异性，在自然宿主内大多数病毒呈隐性感染，但人和虎皮鹦鹉多瘤病毒对宿主有一定致病性。本文就有关多瘤病毒的感染和生物学特性研究进展作一概述