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201.
针对大规模多输入多输出(multiple-input multiple-output,MIMO)系统存在的信号检测计算复杂度高、检测精度不足等问题,参考OAMP-Net算法思想,引入残差结构,提出了一种新的智能信号检测网络模型ROAMP-Net。将正交近似消息传递(orthogonal approximate message passing,OAMP)估算信号的迭代过程展开为深度学习网络,同时引入残差结构,分别对各网络层的线性和非线性估计值进行逐层修正,有效防止估计误差的前向传播和过程积累,避免网络模型随着网络层数增加而发生性能退化,从而提高最终信号检测的准确度。针对不同调制方式和不同天线阵列的系列仿真实验结果表明,不同调制方式和天线阵列下ROAMP-Net在检测准确度上均有不错的性能表现。 相似文献
202.
提出了一种新的用于未知数量稀疏源的盲分离的统一方法.为了改善聚类分离的精度,首先选取混合空间中半径给定、中心位于原点的超球面以外的数据点,并将这些数据点映射到中心位于原点的单位超球面上.由此,原来的超平面线性聚类变为致密聚类,各聚类互相重叠的现象消失.然后,通过对这些映射到单位超球面上的数据点进行聚类分离来估计混合矩阵,再利用混合矩阵估计源,其中最佳不相似阈值和相应的聚类数量是自动生成的.仿真实验验证了该方法对实际音频信号包括语音信号的有效性.仿真结果表明该方法精确、简便,稳定性好,且计算量较小. 相似文献
203.
提出一种将介质型电磁带隙结构与电源平面分割技术相结合,用于抑制高速电路电源/地平面间同步开关噪声的新方法.利用Ansoft HFSS建立相应三维电磁仿真模型并对其进行数值仿真,结果表明:若以-40 dB为噪声隔离标准,噪声可在0.01~0.66 GHz与0.91~4.11 GHz范围内得到有效抑制,并且噪声最大抑制深度... 相似文献
204.
Pahan K 《Cellular and molecular life sciences : CMLS》2006,63(10):1165-1178
Although a change in life-style is often the method of first choice for lipid lowering, lipid-lowering drugs, in general,
help to control elevated levels of different forms of lipids in patients with hyperlipidemia. While one group of drugs, statins,
lowers cholesterol, the other group, fibrates, is known to take care of fatty acids and triglycerides. In addition, other
drugs, such as ezetimibe, colesevelam, torcetrapib, avasimibe, implitapide, and niacin are also being considered to manage
hyperlipidemia. As lipids are very critical for cardiovascular diseases, these drugs reduce fatal and nonfatal cardiovascular
abnormalities in the general population. However, a number of recent studies indicate that apart from their lipidlowering
activities, statins and fibrates exhibit multiple functions to modulate intracellular signaling pathways, inhibit inflammation,
suppress the production of reactive oxygen species, and modulate T cell activity. Therefore, nowadays, these drugs are being
considered as possible therapeutics for several forms of human disorders including cancer, autoimmunity, inflammation, and
neurodegeneration. Here I discuss these applications in the light of newly discovered modes of action of these drugs.
Received 5 September 2005; received after revision 29 December 2005; accepted 26 January 2006 相似文献
205.
Based on the classification of bacterial lipolytic enzymes, family I.3 lipase is a member of the large group of Gram-negative
bacterial true lipases. This lipase family is distinguished from other families not only by the amino acid sequence, but also
by the secretion mechanism. Lipases of family I.3 are secreted via the well-known type I secretion system. Like most of proteins
secreted via this system, family I.3 lipases are composed of two domains with distinct yet related functions. Recent years
have seen an increasing amount of research on this lipase family, in terms of isolation, secretion mechanism, as well as biochemical
and biophysical studies. This review describes our current knowledge on the structure-function relationships of family I.3
lipase, with an emphasis on its secretion mechanism.
Received 18 April 2006; received after revision 3 July 2006; accepted 24 August 2006 相似文献
206.
Src-family kinases (SFKs) regulate different granulocyte and monocyte/macrophage responses. Accumulating evidence suggests that members of this family are implicated in signal transduction pathways regulating phagocytic cell migration and recruitment into inflammatory sites. Macrophages with a genetic deficiency of SFKs display marked alterations in cytoskeleton dynamics, polarization and migration. This same phenotype is found in cells with either a lack of SFK substrates and/or interacting proteins such as Pyk2/FAK, c-Cbl and p190RhoGAP. Notably, SFKs and their downstream targets also regulate monocyte recruitment into inflammatory sites. Depending on the type of assay used, neutrophil migration in vitro may be either dependent on or independent of SFKs. Also neutrophil recruitment in in vivo models of inflammation may be regulated differently by SFKs depending on the tissue involved. In this review we will discuss possible mechanisms by which SFKs may regulate phagocytic cell migratory abilities. 相似文献
207.
Two major functions of the Golgi apparatus (GA) are formation of complex glycans and sorting of proteins destined for various
subcellular compartments or secretion. To fulfill these tasks proper localization of the accessory proteins within the different
sub-compartments of the GA is crucial. Here we investigate structural determinants mediating transition of the two glycosyltransferases
β-1,4- galactosyltransferase 1 (gal-T1) and the α-1,3-fucosyltransferase 6 (fuc-T6) from the trans-Golgi cisterna to the trans-Golgi network (TGN). Upon treatment with the ionophore monensin both glycosyltransferases are found in TGN-derived swollen
vesicles, as determined by confocal fluorescence microscopy and density gradient fractionation. Both enzymes carry a signal
consisting of the amino acids E5P6 in gal-T1 and D2P3 in fuc-T6 necessary for the transition of these glycosyltransferases from the trans-Golgi cisterna to the TGN, but not for their steady state localization in the trans-Golgi cisterna.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users.
Received 30 July 2008; received after revision 17 September 2008; accepted 29 September 2008 相似文献
208.
高动态GPS/INS组合导航算法研究 总被引:5,自引:0,他引:5
首先介绍了新型深组合GPS/INS系统原理图及组合导航滤波算法。在该算法中,组合卡尔曼滤波器除完成INS误差及GPS接收机时钟误差的估计外,还参与了GPS码跟踪,即完成传统码跟踪环中环路滤波器的功能。采用自适应码跟踪误差估计器补偿组合卡尔曼滤波器测量值中的相关分量,从而消除了传统组合中不稳定的主要根源。然后进行了计算机仿真计算,仿真结果表明,新型深组合GPS/INS导航算法适用于机动性较高的载体。 相似文献
209.
直扩信号的谱检测和神经网络估计 总被引:27,自引:5,他引:22
论述了二次谱理论、谱相关理论和神经网络方法在直接序列扩频(DS/SS)信号的检测与估计中的应用,提出了利用谱分析结合神经网络的方法来实现对低信噪比DS/SS信号的参数及其伪码(PN)序列的估计.计算机模拟结果表明,该方法在较低的输入信噪比条件下能良好地工作. 相似文献
210.