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951.
在20世纪高等教育改革中,大学生综合素质和创新能力的培养,是其中重要的组成部分.本文依据现代教育理论,探讨了大学物理教学过程中培养学生思维能力的策略和方法.  相似文献   
952.
浅议高校学报编辑的信息素质和敬业精神   总被引:2,自引:0,他引:2  
编辑素质既包括以知识能力和信息处理为特征的智力因素,也包括以兴趣、爱好、敬业精神为特征的非智力因素。从当前高校学报编辑部的人员组成看,以知识为特征的学历资格和以能力为特征的工作资历一般都符合要求,而以信息处理为特征的岗位适应性,即编辑的信息素质却急待提高。至于非智力因素方面,由于当前高校管理政策的导向和市场经济、物质利益的驱动,如何发扬高校学报编辑的敬业精神,更是当务之惠。本试图从理论上对高校学报编辑的信息素质和敬业精神作一些深入讨论。  相似文献   
953.
学校心理素质教育评价是一项系统工程,探讨其基本原则、基本标准、基本过程和主要评价类型及其实施条件,是学校心理素质教育评价首先要解决的理论问题.  相似文献   
954.
Expression vector pBPC102, which carries winged bean lysine-rich protein (wblrp) gene and dihydropicolinate synthase (DHDPS) gene, was transferred into hexaploid winter wheat cv. Jinghua No.l, Jing411, You899 and Yangnongl5 explants of immature inflorescence and immature embryos by particle bombardment. More than 100 transgenic plants were obtained under the selection of s-(2-aminoethyl)-L-cysteine (AEC). Confirmed transgenic plants of To and TI generation by PCR and PCR-Southern blotting analyses showed successful integration of wblrp gene into wheat genome. Analysis of transgenic plant lines of T2 by Northern dot-blotting showed good expression of wblrp gene in offspring seed. The content of free lysine in leaves, contents of bound lysine and total proteins in seeds of T2 transgenie wheat lines were determined and analyzed. Among 34 tested transgenic lines, levels of free lysine content in leaves of 9 transgenic lines are 2~3times higher than un-trans-formed wild-type cultivars. Among 17 analyzed transgenic lines, bound lysine content of 4 transgenic lines is more than 10% higher than that of wild-type cultivars. Our research suggests that introducing wblrp gene into wheat is an effective way to improve its nutrition quality.  相似文献   
955.
Neurobiology and neuroimmunology of Tourette’s syndrome: an update   总被引:4,自引:0,他引:4  
Tourettes syndrome is a childhood-onset neuropsychiatric disorder characterized by the presence of both multiple motor and vocal tics. While the pathogenesis at a molecular and cellular level remains unknown, structural and functional neuroimaging studies point to the involvement of the basal ganglia and related cortico-striato-thalamo-cortical circuits as the neuroanatomical site for Tourettes syndrome. Moreover, Tourettes syndrome has a strong genetic component, and considerable progress has been made in understanding the mode of transmission and in identifying potential genomic loci. Summaries of recent findings in these areas will be reviewed, followed by a critical overview of findings both supporting and challenging the proposed autoimmune hypothesis of Tourettes syndrome. We conclude that Tourettes syndrome is a heterogeneous disorder, and that immune factors may indeed be involved in some patients.Received 12 August 2003; received after revision 8 October 2003; accepted 31 October 2003  相似文献   
956.
Misfolded or incompletely assembled multisubunit glycoproteins undergo endoplasmic reticulum-associated degradation (ERAD) regulated in large measure by their N-linked polymannose oligosaccharides. In this quality control system lectin interaction with Glc3Man9GlcNAc2 glycans after trimming with endoplasmic reticulum (ER) -glucosidases and -mannosidases sorts out persistently unfolded glycoproteins for N-deglycosylation and proteolytic degradation. Monoglucosylated (Glc1Man9GlcNAc2) glycoproteins take part in the calnexin/calreticulin glucosylation-deglucosylation cycle, while the Man8GlcNAc2 isomer B product of ER mannosidase I interacts with EDEM. Proteasomal degradation requires retrotranslocation into the cytosol through a Sec61 channel and deglycosylation by peptide: N-glycosidase (PNGase); in alternate models both PNGase and proteasomes may be either free in the cytosol or ER membrane-imbedded/attached. Numerous proteins appear to undergo nonproteasomal degradation in which deglycosylation and proteolysis take place in the ER lumen. The released free oligosaccharides (OS) are transported to the cytosol as OS-GlcNAc2 along with similar components produced by the hydrolytic action of the oligosaccharyltransferase, where they together with OS from the proteasomal pathway are trimmed to Man5GlcNAc1 by the action of cytosolic endo--N-acetylglucosaminidase and -mannosidase before entering the lysosomes. Some misfolded glycoproteins can recycle between the ER, intermediate and Golgi compartments, where they are further processed before ERAD. Moreover, properly folded glycoproteins with mannose-trimmed glycans can be deglucosylated in the Golgi by endomannosidase, thereby releasing calreticulin and permitting formation of complex OS. A number of regulatory controls have been described, including the glucosidase-glucosyltransferase shuttle, which controls the level of Glc3Man9GlcNAc2-P-P-Dol, and the unfolded protein response, which enhances synthesis of components of the quality control system.Received 26 January 2004; accepted 25 February 2004  相似文献   
957.
中国民营企业易“短寿”是内外部多种不良因素造成的,其中企业主素质不高是重要的内因。随着我国社会主义市场经济体制的不断完善和民营企业外部环境的不断改善,民营企业的发展壮大更多的取决于企业的内部因素,尤其是企业主思想文化素质、专业技术水平、经营管理能力和责任意识的提高。  相似文献   
958.
翻译教学作为素质教育的一个重要组成部分,必须体现素质教育三大基本特征主体性、发展性和全面性.以任务型翻译教学模式为例,在翻译教学中,互动任务的完成应以"主题活动"为线索、"合作式学习"为原则,进而达到培养学生翻译能力的目的.  相似文献   
959.
从基础教育改革的重要性和目前发展的十大趋势,论述了对中学教师素质的高新要求.论述了高师人才培养存在培养目标有偏差,人科学与社会科学教育太薄弱,相关专业壁垒未打通,教师专业理论与技能训练严重不足四方面的问题.在高师院校的教学改革中,不仅要强化师范性,还要加强通识教育;重在更新人才培养目标与模式,研制出新的本科教学计划,以求培养出适应素质教育需求的新一代智慧型综合型教师.  相似文献   
960.
以“三个代表”重要思想为指导,从增强“两课”教学内容的时代感和实效性的高度,论述了充实“两课”教学内容是提高教学质量的基础;转变教学观念是提高“两课”教学质量的前提;理论联系实际是增强“两课”教学实效性的关键。论述了提高教学质量应增强“两课”教学内容的时代感;提高“两课”教师的整体素质;强化实践教学环节;保证现代教育技术在“两课”教学中的运用。  相似文献   
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