In-vehicle GPS/DR navigation system development and test results in Singapore

This paper introduces the in-car navigation system prototype development and test results under the context of Singapore. In the system, integrated GPS/DR is used for continuous vehicle positioning. A digital road network map database is built for the whole Singapore. The database is designed to support map matching, route determination, and route guidance functions. The prototype system demonstrates GPS positioning of the vehicle in real-time, tracking the vehicle onto a digital map with fix updates every one or two seconds.With the map matched vehicle location on the map, voice and/or text guidance is provide to the driver. The vehicle position can also be transferred to control centre through communication data link for the purpose of fleet management.     

Effects of hyaluronic acid－chitosan－gelatin complex on the apoptosis and cell cycle of L929 cells

With the development in the field of tissue engineering, the interaction between biomaterials and cells has been deeply studied. Viewing the cells seeded on the surface of materials as an organic whole, cell cycle and apoptosis are analyzed to deepen the study of cell compatibility on biomaterials, while cell proliferation and differentiation are studied at the same time. In this paper, hyaluronic acid is incorporated into the chitosan-gelatin system. Propidium iodide (PI) was used in cell cycle analysis and the double-staining of cells with annexin-V and PI was applied in cell apoptosis analysis. The results show that incorporated hyaluronic acid shortens the adaptation period of cells on the material surface, and then cells enter the normal cell cycle quickly. In addition, added hyaluronic acid inhibits cell apoptosis triggered by the membranes. Therefore, hyaluronic acid improves the cell compatibility of chitosan-gelatin system and benefits the design of biomimetic materials.     

Inhibitory effect of the adenovirus type 5 E1A protein expressed in the yeast system of the human tumor cell growth

Adenovirus 5 type E1A as a tumor suppressor gene can inhibit tumor growth and enhance the censitivity of chemotherapy and radiotherapy.E1A have the ability to integrate into the host genome,resulting in long-time expres-sion that induces Rb gene inactivation and animal cells im-mortalization.This prompted us to select the E1A protein for treatment of cancer in order to overcome the limitations of E1A gene therapy.Thus,we firstly comstructed E1A eu-caryotic expression vector (pPIC9/E1A),transformated the pichia pastoris yeast cells(GS115) and screened the high-expressing recombinant strains.The positive yeast strains were cultured in the shake flask,and induced for 3d.The crude E1A protein was purified using two steps of col-umu chromatography on HiTrap Q and HiTrap SP.The pu-rified E1A protein was identified by SDS-PAGE and Western blot.E1A protein was mostly located at cellular unclear when Cheriot delivered E1A protein into cells.The analysis in vitro indicated that the E1A protein arrested LN686 cell cycle at G2/M phase,and significantly inhibited the growth of LN686 tumor cells.The current studies firstly provided an experimental basis to further develop E1A protein for tumor treatment.     

轿车车头道路模拟试验加载谱研究

结合实际工作需要，通过远程参数控制技术在6通道多轴随机振动台上开发了轿车车头内零部件的室内道路模拟试验技术，正确、快速地模拟试件在试车场强化道路上的振动特性，缩短了试验周期，降低了试验费用，建立了制定试验标准的基本流程。     

城市卷烟配送线路的网格划分算法

成本与服务是现代物流的两大主题，配送中心不同送货线路间的工作量均衡是线路划分的一个重要目标，它体现了配送中心的工作效率和对客户的物流服务质量．以浙江省烟草公司杭州分公司物流6400多户卷烟零售网点配送网络为数据源，采取“相邻合并、密集成簇、由簇扩展”思想，进行llO多条送货线路的网格划分和算法求解，内容包括不同送货线路之间的广义工作量均衡、网点密集簇和关键边的定义与遴选、密集簇的向外搜索扩展等．     

汽车综合性能分布式计算机网络自动测控系统

在分析传统的汽车安全性能自动测控系统各种控制方案优缺点的基础上,采用分布式计算机网络控制方式,实现了对汽车综合性能的自动检测与控制。同时对该系统的整体结构、基本工作原理、控制流程及软件设计方法进行了论述。结果表明,分布式计算机网络控制方式是一种解决汽车综合性能自动检测与控制问题的有效方法,能够更好地满足汽车综合性能检测的实际需要。     

JT6100SD新型双层客车操纵稳定性

针对大型客车的结构特点,分析了影响大型客车操纵稳定性的因素,并对相关参数进行了计算。计算结果均满足相关规范要求,提出了进一步改善其操作稳定性的建议措施。     

熔融碳酸盐燃料电池阴极材料制备与导电性

研究了熔融碳酸盐燃料电池（MCFC）阴极材料锂铁氧化物电极的导电性能。实验结果表明在合成锂铁氧化物的过程中，使Li2CO3轻微过量，可以提高锂铁氧化物电极的导电性。在同一温度下，随着Li:Fe值的增大，锂铁氧化物电极的导电性增加。相同Li:Fe条件下，锂铁氧化物电极的导电性随着温度升高按指数规律增加。扫描电镜研究（SEM）表明，Li:Fe比值不同，制备的锂铁氧化物电极表面形貌也不同。     

一种DSM模型下飞行障碍物尺度的研究

在一种数字表面模型(DSM)建模方法的基础上,对威胁飞行器低空飞行安全的独立障碍物的尺度与DSM纵横断面采样间距的关系进行了分析,给出了独立障碍物的定义、分类和确定独立障碍物的方法。通过对7.2km2一典型城市地域的仿真试验表明,DSM纵横断面间距在3～25m之间,威胁飞行器地形跟踪制导安全的孤立障碍物较少,同时装订并实时处理的DSM模型数据量也较小,并在纵横断面间距12.5m处达到两者最优。     

地面防空武器系统作战训练效能综合评估研究

通过对地面防空武器系统性能的分析，建立了其作战训练效能综合评判的指标体系，运用判断矩阵校正法改进了权重的确定，并采用层次分析和判断矩阵相结合的方法对地面防空武器系统作战训练实例的效能进行了综合评估研究。