Finding finer functions for partially characterized proteins by protein-protein interaction networks

Based on high-throughput data, numerous algorithms have been designed to find functions of novel proteins. However, the effectiveness of such algorithms is currently limited by some fundamental factors, including (1) the low a-priori probability of novel proteins participating in a detailed function; (2) the huge false data present in high-throughput datasets; (3) the incomplete data coverage of functional classes; (4) the abundant but heterogeneous negative samples for training the algorithms; and (5) the lack of detailed functional knowledge for training algorithms. Here, for partially characterized proteins, we suggest an approach to finding their finer functions based on protein interaction sub-networks or gene expression patterns, defined in function-specific subspaces. The proposed approach can lessen the above-mentioned problems by properly defining the prediction range and functionally filtering the noisy data, and thus can efficiently find proteins’ novel functions. For thousands of yeast and human proteins partially characterized, it is able to reliably find their finer functions (e.g., the translational functions) with more than 90% precision. The predicted finer functions are highly valuable both for guiding the follow-up wet-lab validation and for providing the necessary data for training algorithms to learn other proteins.     

选择性催化氧化H2S的催化剂研究

在考察了几种单组分氧化物把硫化氢催化氧化为单质硫的基础上，采用共沉淀法合成了3种复合氧化物催化剂A，B，C，并考察了它们的催化活性和选择性．结果表明，在一定条件下，催化剂B的转化率和选择性分别在90％和97％以上，在40h的催化性能稳定性测试中，其转化率和选择性均能保持稳定，具有良好的催化性能．     

地基基础-坝体体系动力特性及地震反应分析的有限元与无限元耦合法

编制了有限元及有限元—无限元耦合计算程序，利用其分析了广西源口拱坝在有限域及无限域地基下的动力特性与动力响应，并与常规刚性地基下坝体的动力特性、动力响应进行比较，得出结论：1．弹性地基下拱坝自振频率减小、动位移最大值增大；2．耦合分析法具有较高的精度和显著的经济性，是工程应用中值得推广的一种分析方法。     

无机化学中共价键类型及其在元素周期表中变化规律

无机化学中常见共价键有双电子σ键(包括σ配键)、双电子π键、单电子键、三电子键、离域π键、多中心键、反馈π键(包括d-pπ键、d-dπ键和π←dπ键)等.不同化学键的形成,对物质性质有着重要影响.本文主要讨论无机化合物中常见共价键形成条件和特征,对物质性质影响及其在元素周期表中变化规律.     

Electrocatalytic Oxidation of H_2 O_ 2 at a Carbon Paste Electrode Modified with a Nickel (Ⅱ)-5,11,17,23-Tetra-Tert-Butyl-25,27-Bis(Diethylcarbamoylmethoxy)Calix[4] Arene Complex and Its Application

0　IntroductionThegreatimportanceofnickelelectrochemistryinalkalinemedium ,especiallyforpotentialapplication ,hasattractedmuchattetionofresearcherseithertostudythebehaviorofnickel basedelectrodeitselforitsactivitytowardsothermolecules.Manyreportsshowedthatthenickelbasedelectrodeshaveelectro catalyticactivityforreactionsofappliedinterest,suchaselectro chemicaldeterminationofantioxidantsinfood[1 ] ,detectionofni tricoxide (NO )insolution[2 ] ,electrocatalyticoxidationofmethanol[1 ] ,alcohol[3] ,…     

用于人机交互的交流式电磁跟踪系统的研究

虚拟现实系统和计算机仿真系统中广泛采用电磁跟踪系统测量用户的头部或手部的位置和姿态来实现人机交互。本文分析了目前已有的直流式电磁跟踪系统的不足，提出了一种采用交流信号作激励源的交流式电磁跟踪系统，研究了该系统的结构，推导了用于提取传感器接收信号的递推数字互相关算法，讨论了算法参数与算法性能的关系。仿真实验证明了算法的有效性及理论分析的正确性。本文的研究成果为实际的交流式电磁跟踪系统的设计提供了理论依据。     

使用Dreamweaver UltraDev制作

介绍了用DreamweaverUltraDev来实现动态网页的优点 ,并给出实例剖析 .     

催化裂解法制备螺旋状碳纳米管的实验研究

在硅片上用直流溅射镀铁的方法制备催化剂 ,通过乙炔在 70 0°C下催化裂解制备碳纳米管 .对热解产物进行了扫描电镜观察和 X射线衍射测试 .本文通过对有氢气预处理和没有氢气预处理两种情况下催化裂解法制备的碳纳米管的形貌、管径大小等性质的研究 ,来初步揭示螺旋状碳纳米管的生长机理 .     

粘结开裂破坏框架柱性能的研究

本文以试验结果为基础,通过轴压力、配筋、配箍、加载方向的变化,分析了这些因素对产生粘结开裂破坏框架柱性能的影响,并给出了产生粘结开裂破坏的m值下限。