稳定非线性动力系统周期的计算机分析

提出采用后继函数法来确定非线性动力系统的周期,并编制计算机程序对Ｖａｎ ｄｅｒ Ｐｏｌ方程实例计算周期和绘制相图,结果表明,该方法计算结果准确且实用性强,本方法不但适合于求解保守系统和具 周期解非线性动力系统的周期,也适合于耗散系统和不稳定系统的分析。     

危险评价的广义突变理论

引入分析力学,泛函分析和变分原理,对系统危险性进行分析,在系统安全理论和泛涵的基础上建立了危险评价的突变模型,发展了事故分析及危险评价的更高层次的突变理论,称之为危险评价的广义突变理论,通过两个典型实例,介绍了广义突变理论的应用方法。     

烯烃的分子距离边数矢量(μ)及沸点的估计与预测

基于双键相对于单键键长的大小,提出了烯烃的分子距离边数（ＭＤＥ）矢量（μ矢量）;进而通过多元线性回归方法建立μ矢量与烯烃沸点之间的关系模型并进行预测,计算沸点与实验值之间的均方根误差仅为３．７８Ｋ,相关系数为０．９９９３。     

信号流图的扩展及其应用

将信号流图扩展到状态空间构成所谓向量流图,用公式可实现组合系统规范化;按工答过程绘制信号流图构成所谓过程流图,可对系统组件作深入的分析。     

两个线性最小二乘问题解流形之间的逼近性

运用广义逆矩阵理论,研究了两个线性最小二乘问题解流形之间的逼近性,推广了若干已有结论。     

Cloning, construction of prokaryotic expression vector and expression ofEscherichia coli cytosine deaminase gene

Cytosine deaminase gene ofEscherichia coli strain H-30 was cloned, and its initiation codon of ‘GTG’ was mutated to ‘ATG’ by PCR. Prokaryotic recombinant expression vector pBV220-CD was constructed. Clone with high enzyme activity were selected by detecting their specific activity of cytosine deaminase. 5-FC(5-FC, 5-fluorocytosine) could induce the lethal toxicity to cells containing active CD gene. DNA sequence analysis indicated that there were 16 altered bases and 5 of them resulted in the alteration of amino acids in predicted peptide by comparing DNA sequence of the clone H-30-CD-11 with high enzyme activity with CD gene reported in Gene Bank.     

Research advances in gene therapy for Parkinson's disease

During the long period of time when people have been seeking for an effective therapeutic method for PD, the gene therapy has shown greater and greater advantages over other methods. It can be performed mainly in two ways: ex vivo and in vivo. With the former, TH gene as well as some neurotrophic factor genes (such as GDNF, BNDF genes) can be invited to some cell lines or primary cells thus forming engineered cells and then implanting them into brain. While with the latter, viral vectors including HSV-1, Ad, AAV that can be utilized to construct recombinant viruses, or non-virus vectors can be used to delived DNA into brain directly. The present review summarizes the recent research advances in the gene therapy for PD, and it is reasonable for us to predict a notable progress in prevention and treatment for PD in the next decade.     

拟协调轴对称三结点退化壳单元

结合拟协调有限元方法和退化壳有限元概念,构造了一个轴对称三结点退化壳单元,采用了整体,局部和等参三个坐标系,使用与拟协调单元列式方法等效的基于胡－鹫津广义为分原理的杂交／混合单元列式方法构造轴对称三结点退化壳单元;使用相同的等参坐标插值来假设应力和应变,插值既考虑到低阶项的完备,又借鉴了拟协调九结点四边形爱化壳单元的结构经验。为了确定应力应变的插值形式,进行了多次数值试验和单元刚度矩阵的特征值分析     

二元矩阵值分叉连分式插值的矩阵算法

本文给出了一个计算二元矩阵分叉连分式插值的系数算法以及与此算法等价的矩阵算法,这种算法是用矩阵广义逆意义下定义的矩阵行、列初等变换而给出的．     

镦粗工艺理论与技术的进展

提出了普通平板间镦粗圆柱体高径比Ｈ／Ｄ〉１时刚塑性力学模型的拉应力理论和高径比Ｈ／Ｄ〈１的静水应力力学模型的剪应力理论,前者打破了传统工程塑性力学中所阐述的镦粗体内部总处于三向压应力之说,后者圆满地解释了大型饼类锻件中常出现的“夹馅饼”缺陷问题,平板镦粗所理论已被定性物理模拟和定量数值模拟,广义滑移线解,力学分块法和生产解剖试验所证实,在该新理论基础上,进一步提出方柱镦粗的两个新力学模型,锥形板镦