The effect of ethanol on the biosynthesis and regulation of opioid peptides

Summary Alcoholism and alcohol abuse are serious health problems. Alcohol is known to influence the activity of a number of biological systems, for example the hormonal and neuronal systems. One of the biological systems whose activity is greatly influenced by alcohol is the endogenous opiate system. Alcohol modifies the function of both opiate receptors and opioid peptides. In fact it has been proposed that many of the effects of ethanol are mediated by its effects on the endogenous opiate system. This review will present results from various laboratories on the effects of acute and chronic ethanol treatments on various species, and on the release, biosynthesis and post-translational processing of the endorphins, enkephalins and dynorphins, the three known families of endogenous opioid peptides. Furthermore, the effect of acute and chronic ethanol consumption on the -endorphin system in man, and the possible implications of the functional activity of the endogenous opiate system for the genetic predisposition to alcoholism will be discussed.     

On analytical treatment of all boundary and volume integrals in BEM

In this paper, the integrals appeared in BEM model for Poisson equation are all implemented analytically. Wherein, the boundary and the domain are discretized by linear boundary elements and linear internal triangle cells respectively. The closed formulations for all integrals are presented so that the computer effort for numerical solution is reduced considerably with higher accuray. The numerical example shows that the results are more accurate in comparision with Gaussian integration in the same discrezition. The basic idea of this paper could be extended to BEM model for Helmholtz equation and/or the time-dependent second other differential equations. Supported by the National Natural Science Foundation of China Tang Shaowu: born in 1971, Ph. D.     

二元矩阵值分叉连分式插值的矩阵算法

本文给出了一个计算二元矩阵分叉连分式插值的系数算法以及与此算法等价的矩阵算法,这种算法是用矩阵广义逆意义下定义的矩阵行、列初等变换而给出的．     

A（n,4）与A（n,5）的精确公式与简单公式

设Ａ（ｎ,ｋ）表示不定方程ｋ∑ｉ＝１ｉｘｉ＝ｎ非负整数解的个数,给出了Ａ（ｎ,４）与Ａ（ｎ,５）的精确公式及求得应简单公式的方法。     

具有排除体积的两维高分子链的静态标度律

运用四位置模型对具有排除体积的两维高分子链进行ＭｏｎｔｅＣａｒｌｏ模拟和标度分析,为了提高长链的抽样效率,还提出了被称为“链段伸展法”的抽样方法。对单个自避行走链的模拟结果表明,两维ＳＡＷ链有育明显不同于夫规飞行链以及三维ＳＡＷ链的特点。     

公路客运量预测方法的比较

科学准确地预测公路客运量,超前掌握公路客运量发展的趋势、特点、规律和数量,是制定公路客运发展和站场配置规划的基础。运用灰色模型、指数平滑模型、回归分析法、弹性系数法等多种预测模型对某城市2003~2015年公路客运量进行了分析预测,通过残差分析和绝对百分误差(MAPE)进行择优,提高了预测精确度。最后采用组合预测确定终值并进行了分析比较。结果表明,组合预测综合考虑了各种因素的影响,能够提高公路客运量预测精度,为公路客运发展提供科学决策依据。     

三种体绘制算法的比较

体绘制技术是一种能够准确反映出数据内部信息的可视化技术，本文介绍了3种常用体绘制算法：光线投射算法，足迹算法和错切-变形算法的基本思想，在此基础上比较了它们的性能并对它们的改进作了进一步的讨论，最后给出了结论并对这3种算法的前号作出了的展望．     

开放性尘源粉尘运动轨迹的数值计算

在对粉尘颗粒在大气中受力状况进行分析的基础上 ,采用颗粒随机轨道模型对尘源表面的粉尘在大气中的运动轨迹进行了数值计算 ,再现了野外现场观测的现象 ,从而证明了数值计算的可靠性 .利用ParticleSourceinCell算法 ,计算了由开放性粉尘造成的大气含尘质量分数 ,为定量预测露天矿粉堆料对环境造成的污染提供了依据 .     

滑动摩擦现象微观机理初探

从金属的微观机理方面分析研究了摩擦的起因，探讨了静摩擦力大于动摩擦力的原因，指出了影响滑动摩擦的主要因素。