有限维修连续(Q,S)库存模型

本文讨论一种库存、维修综合模型,其中需求、维修时间和滞后期均为随机现象.以马尔科夫过程为出发点并引用排队论中的某些结果,对系统的稳态行为作出定量分析,得到各种系统评估,包括帐面及实际库存的分布和均值,并建立目标函数.     

试论应县木塔不落地(架)维修的可行性

近年来,我国十分重视历史文物及古建筑的保护及维修。应县木塔是我国著名的文物,亟需维修。本文论述了采用分层提升木塔,不落地就位维修的可行性。     

Roles of the DNA mismatch repair and nucleotide excision repair proteins during meiosis

Numerous proteins are involved in the nucleotide excision repair (NER) and DNA mismatch repair (MMR) pathways. The function and specificity of these proteins during the mitotic cell cycle has been actively investigated, in large part due to the involvement of these systems in human diseases. In contrast, comparatively little is known about their functioning during meiosis. At least three repair pathways operate during meiosis in the yeast Saccharomyces cerevisiae to repair mismatches that occur as a consequence of heteroduplex formation in recombination. The first pathway is similar to the one acting during postreplicative mismatch repair in mitotically dividing cells, while two pathways are responsible for the repair of large loops during meiosis, using proteins from MMR and NER systems. Some MMR proteins also help prevent recombination between diverged sequences during meiosis, and act late in recombination to affect the resolution of crossovers. This review will discuss the current status of DNA mismatch repair and nucleotide excision repair proteins during meiosis, especially in the yeast S. cerevisiae. Received 21 September 1998; received after revision 23 November 1998; accepted 23 November 1998     

Initiation of cancer and other diseases by catechol ortho-quinones: a unifying mechanism

Exposure to estrogens is a risk factor for breast and other human cancers. Initiation of breast, prostate and other cancers has been hypothesized to result from reaction of specific estrogen metabolites, catechol estrogen-3,4-quinones, with DNA to form depurinating adducts at the N-7 of guanine and N-3 of adenine by 1,4-Michael addition. The catechol of the carcinogenic synthetic estrogen hexestrol, a hydrogenated derivative of diethylstilbestrol, is metabolized to its quinone, which reacts with DNA to form depurinating adducts at the N-7 of guanine and N-3 of adenine. The catecholamine dopamine and the metabolite catechol (1,2-dihydroxybenzene) of the leukemogen benzene can also be oxidized to their quinones, which react with DNA to form predominantly analogous depurinating adducts. Apurinic sites formed by depurinating adducts are converted into tumor-initiating mutations by error-prone repair. These mutations could initiate cancer by estrogens and benzene, and Parkinson's disease by the neurotransmitter dopamine. These data suggest a unifying molecular mechanism of initiation for many cancers and neurodegenerative diseases and lay the groundwork for designing strategies to assess risk and prevent these diseases. Received 4 September 2001; received after revision 28 November 2001; accepted 2 December 2001     

CDMA无线图像传输技术在消防应急通信中的应用

通过论述消防应急平台的定义、组成及建设模式,介绍应急指挥系统的特点及功能等,来论述CDMA无线图像传输技术在消防工作中的应用。     

CDMA无线图像传输技术在消防应急通信中的应用

通过论述消防应急平台的定义、组成及建设模式，介绍应急指挥系统的特点及功能等，来论述CDMA无线图像传输技术在消防工作中的应用。     

用网络层次分析法（ANP）评估应急桥梁设计方案

主要介绍了应用网络层次分析法(ANP)评估应急桥梁设计方案的基本步骤.ANP在综合考虑各种因素的同时,考虑到因素间的相互影响,对各因素间的依赖的反馈关系进行了描述和计算,最后进行综合排序.利用超级决策SD(Super Decisions)软件很方便的计算了一个实例,计算结果表明,应用ANP评估应急桥梁设计方案是合理的.     

煤矿安全生产预防预警机制和应急预案及其关键技术研究

分析了煤矿建立事故预警机制及应急预案的必要性,探讨了重大事故应急预案的核心要素,展望了煤矿应用预警机制和应急预案的前景。     

突发公共事件应急管理中公权力与私权利的协调

在突发公共事件应急管理中,如何协调好国家公权力和公民私权利之间的关系既是解决突发公共事件本身的需要,也是建设和谐社会的内在要求,还是国际人权保护的必然要求。在突发公共事件应急管理中,必须牢固树立法治理念,同时在比例原则、行政公开原则、权责统一原则等一般原则及公权力优先原则、有限行政紧急权原则、有限救济原则、基本人权不得克减原则等特殊原则的指导下,通过建立和完善突发事件分级、公民抵制权、国家赔偿、信息公开等一系列具体的制度,切实协调好公权力与私权利之间的关系。     

植物对土壤重金属污染修复的研究进展

对植物提取、植物钝化和植物挥发等植物修复技术类型及植物修复机理,包括植物本身分泌特殊物质来螯合溶解难溶性金属;通过某些微生物或微生物与植物的共生体促进植物对重金属的吸收;通过一些土壤改良措施如螯合剂、酸性肥料等的施用增加重金属的有效性,从而提高植物对重金属的提取效率等做了简要论述。分析了目前该研究领域存在的主要问题,以期为修复重金属污染土壤的研究和实践提供参考。