带孔圆柱面的离散方法

本文利用几何变换使圆柱面的离散工作在平面上进行。并应用二次投影变换以减少计算三角形单元节点坐标的时间。所用方法具有直观性与精确性,并能容易地发现计算中的错误。     

环保投资在国民生产总值中所占比重的研究

本文建立了把经济发展、人口增长与环境治理需求联系在一起的数学模型。运用系统工程的多目标线性规划框架构造了二级递阶优化的算法结构,从按15个产业部门编制的经济环境投入产出表出发,研究各部门环保投资占本部门最终产品的比重和各部门对治理“三废”(废水、废气、废渣)的投资分配,进而在此基础上确定总环保投资占国民生产总值的合理比重。文中给出模型可用于工业行业的仿真实例及结果分析。     

平衡增长与不平衡增长的价值取向对经济发展的不同意义

平衡增长与不平衡增长是经济发展理论的两种不同观点，这两种观点存在着共同的偏差，即将经济发展过分寄托于计划的安排，忽视了市场在经济发展过程中的基础作用，忽视了部门和地区在平衡增长与不平衡增长中所存在的有机联系。文章以中国的经济发展为例，对比了不同时期的地区和部门在平衡增长与不平衡增长中的不同表现，论证了市场机制的基础作用对经济发展的重要作用。     

屏幕菜单的开发与应用

在分析ＡＵＴＯＣＡＤ绘图软件中标准菜单结构的基础上，介绍了ＣＡＤ屏幕菜单的开发方法与应用。     

An immunohistochemical study of the clearance of apoptotic cellular fragments

We investigated the distribution and fate of apoptotic bodies during human development and in the adult, using an antibody (M30) that recognizes a neo-epitope formed early in the apoptotic cascade by caspase cleavage of cytokeratin 18. In the fetus, we found extensive accumulation of M30-positive, non-phagocytosed fragments in the red pulp of the spleen, subcutaneous and submucosal vessels, the interstitium of the lung, and the glomerular mesangium of the kidneys. In the liver, M30-immunoreactive fragments were found inside macrophages in the sinusoids. The number of these fragments and the intensity of the immunostaining increased with the gestational age of the fetus. In the adult, M30-positive fragments were barely detectable in normal tissues. However, many pathological situations, including both chronic degenerative processes and metastatic cancer, were associated with accumulation of M30-positive fragments in the red pulp of the spleen. In the liver and kidney, no fragments could be detected. Remarkably, 13 of the 16 patients with metastasized cancer showed pronounced accumulation of M30-positive fragments containing hematoxylin-reactive material in the red pulp of the spleen. In the non-cancerous cases, such DNA-containing fragments were only seen in 9 of 94 cases. The results show that when apoptotic activity is high, as during development in the fetus or during metastasis and other pathological processes in the adult, the phagocytic clearance of apoptotic bodies can be overloaded. These apoptotic fragments then accumulate in the spleen. The visual detection of apoptotic fragments is concluded to reflect increased cell turnover. Received 1 July 2002; accepted 1 July 2002     

The Ror receptor tyrosine kinase family

Receptor tyrosine kinases (RTKs) participate in numerous developmental decisions. Ror RTKs are a family of orphan receptors that are related to muscle specific kinase (MuSK) and Trk neurotrophin receptors. MuSK assembles acetylcholine receptors at the neuromuscular junction [1, 2], and Trk receptors function in the developing nervous system (reviewed in [3-5]). Rors have been identified in nematodes, insects and mammals. Recent studies have begun to shed light on Ror function during development. In most species, Rors are expressed in many tissue types during development. Analyses of mutants that are defective in the single nematode Ror demonstrate a role in cell migration and in orienting cell polarity. Mice lacking one of the two Ror gene products display defects in bone and heart formation. Similarly, two different human bone development disorders, dominant brachydactyly B and recessive Robinow syndrome, result from mutations in one of the human Ror genes. Received 17 April 2001; received after revision 2 July 2001; accepted 4 July 2001     

重演律的哲学探索

系统阐释"三大重演律"和三个推论,探索了重演律中的偶然和必然、个别和一般、对称与破缺、内环境与外环境等哲学问题,建立重演律方法论,特别是重演方法在模型与模拟、教学法以及文学艺术中的广泛应用的方法,利用重演方法阐明科学、文化、经济加速发展的机制与原理,以及落后国家、落后民族在较短时间赶上先进国家和先进民族的内在机理。     

"中国唱法"的追求

中国声乐艺术应逐步形成能充分体现中华民族音乐风格的有民族代表性的歌唱流派--"中国唱法"."中国唱法"应是融洋贯中的结果,需要我们根据自己的语言和民族气质的特点,根据各剧种、曲种、歌种的不同唱法、音乐风味的个性与共性之不同表现因素,与"美声唱法"中的科学发声方法和有关演唱技巧规范进行有机的结合.     

Effect of matrix metallo-proteinase-26 (MMP-26) during embryo implantation in the mouse

Matrix metalloproteinase-26 (MMP-26, endometase and matrilysin-2), a novel member of the MMPs family, is detected not only in the placenta and uterus, but is widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines. However, the function of MMP-26 in the reproductive system has never been reported. Expression of MMP-26 in mouse embryos and the function of the MMP-26 antibody during mouse embryo implantation was examined for the first time by injecting the uterine horn, immunohistochemistry,in situ hybridization, co-culture of mouse blastocysts and uterine monolayer epithelial cells, Western blot, RT-PCR, Northern blot and zymography. Our results show that there is strong expression of MMP-26 mRNA and protein in the mouse embryo. Furthermore, the MMP-26 antibody dramatically inhibited mouse embryo implantation and significantly inhibited adhesion and outgrowth of mouse blastocysts onin vitro uterine monolayer epithelial cells. At the same time, the MMP-26 antibody inhibited the expression of integrin αV mRNA and protein in a dose-dependent manner. These data suggest that MMP-26 may play a role in some of the tissue-remodeling events associated with the invasion of the endometrium by trophoblast cells and facilitate successfully embryo implantation.     

高新区经济活动与城市地域系统生成的关系

目的研究高新区经济活动对城市地域系统的影响。方法用系统观、区域观从研究开发、生产制造、服务活动3个方面对高新区内部的经济活动及其发展机制进行分析。结果高新区的研发活动包括扩散、传播及联合开发、成果转让、创办企业；生产制造活动包括生产流程的内部分工、产业的前向后向联系和对城市企业的辐射带动；服务活动包括行政服务、中介服务和金融服务。结论高新区对城市地域系统影响很大，协调好二者的相互作用关系，有利于物质、资金、信息、技术等生产要素在城市地域系统内的优化配置，有利于城市经济结构和经济空间结构的优化升级。