Nα-quinaldyl-L-arginine·HCl,a new defensive alkaloid fromSubcoccinella-24-punctata (Coleoptera,Coccinellidae)

The isolation of N-quinaldyl-L-arginine·HCl (1) from the CoccinellidaeSubcoccinella-24-punctata is reported. The structure, first established on the basis of the analysis of the spectral properties of1, has been confirmed by synthesis. The alkaloid is of endogenous origin and markedly deterrent to ants.     

Molecular evidence for increased hematopoietic proliferation in the spleen of the b/b laboratory rat

The splenomegaly and the appearance of a significant number of CFU-E (erythroid colony-forming units) and BFU-E¹ (erythroid burst-forming units) in the Belgrade laboratory rat (b/b) spleen prompted us to analyse further the molecular evidence for increased hematopoietic proliferation in the b/b spleen. Messenger RNAs (mRNAs) specific for globins, proteins for iron transport and deposition and the band 3 protein were used in rat erythropoietic tissues as markers for proliferation and erythroid differentiation. In the b/b spleen, all mRNAs analysed display an erythroid-specific pattern of expression. This analysis also revealed an enhanced level of mRNA for ferritin in the +/b spleen, whereas erythrocyte-specific mRNA production was normal.     

Antiviral activities of anthraquinones,bianthrones and hypericin derivatives from lichens

The antiviral activities of some naturally occurring anthraquinones bianthrones, and hypericin derivatives were compared by the end-point CPE (viral cytopathic effects) method and plaque assays. Under optimal conditions of exposure to light, hypericin, 7,7-dichlorohypericin and 5,7-dichloroemodin exhibited strong inhibitory activity against HSV-1 (herpes simplex virus type 1) in both assays. Partial inactivation of the virus was shown by emodin, 7-chloroemodin and 7-chloro-1-O-methylemodin; the bianthrones and other anthraquinones were found to be inactive. Antiviral activity appeared to be, positively correlated with increasing substitution of chlorine in the anthraquinone structure. In the absence of light, only hypericin and 7,7-dichlorohypericin displayed detectable activity.     

Cyclophosphamide-impaired regulation of hepatic heme metabolism

Summary Im male rats hepatic cytochromes b₅ and P-450 were reduced at different times after treatment with cyclophosphamide (CP) (200 mg/kg i.p. for 3 days). In contrast, microsomal heme did not change until 48 h after the last dose of CP, leading to accumulation of heme in a non-cytochromal form. Parallel to the above changes the heme metabolism showed derangement: -aminolaevulinate synthase, the rate-limiting enzyme in heme synthesis, was depressed and heme oxygenase, the enzyme which catalyzes the oxidative degradation of heme, was increased.     

"微机原理"与"汇编语言"两课整合的教学

《微型计算机原理及应用》与《汇编语言程序设计》是计算机应用专业的两门较重要的基础课程,也是教学难度和学习难度较大的两门课程,文章阐述了如何将这两门课程进行整合的教学改革和实践。     

义务教育课程标准实验教科书·化学两版(人民教育出版社,上海教育出版社)之比较

义务教育课程标准实验教科书.化学是根据新课程标准编写而成的,并实行“一纲多本”,由人民教育出版社和上海教育出版社出版,并同时在全国不同的实验区供九年级学生使用。文章就两版教科书在内容,体系,版面设计,探究性等方面进行探讨和对比,得出结论:两版教科书都较好地体现了课程标准的思想,但就探究性而言,人教版的设计更为仔细,真正做到了以学生为主体。     

评判历史问题的政治性与历史性讨论--兼论邓小平与《中共中央关于建国以来党的若干历史问题的决议》

评判历史问题的标准历来多元化.邓小平在评判中共自身历史问题时,政治性突出些,历史性弱化些.有些问题也实现了政治性与历史性的结合.对毛泽东历史地位、毛泽东思想的概念性定义、<决议>本身的历史地位及实事求是的问题的讨论,可以明显看出邓小平对中共历史问题的论断,基本上经受住了时代的考验.     

一种新的多模式快速匹配算法

提出了一种针对多模式的快速模式匹配算法。算法分为预处理阶段和匹配阶段两个部分，预处理阶段对所有待匹配的模式进行分析，构造一个关于这些模式的树型有限状态自动机，匹配阶段利用这个模式自动机．对文本串进行一次性的搜索，查找文本是否包含模式集中的模式。为了提高了匹配速度，算法利用已匹配的字符串信息实行跳跃式的比较，避免了文本扫描指针的回溯。     

化学实验内容设置与特色经济研究

就高校的实验课内容如何与当地的特色经济的发展有机结合,使之相互促进的现时问题进行了深入的探讨,并对如何开展提出了一些观点及具体的操作方法,对高校实验课的教学和地方特色经济的发展有一定的参考价值.     

ZAO透明导电纳米薄膜中Al元素分布对其性能的影响

主要对直流反应磁控溅射法制备ZAO纳米薄膜中Al元素的相对含量进行了分析,对其作了EDS,XRD测试,并研究了Al质量分数与ZAO薄膜的光、电性能的关系·得出ZAO薄膜中成分是均匀的,具有ZnO晶体结构;Al元素的掺杂没有形成新的化合物(Al2O3),Al对Zn的掺杂替换是提高ZAO薄膜导电性能的关键因素,对薄膜在可见光区的透射性影响不大·制备的薄膜最低电阻率为4 5×10-4Ω·cm,可见光透射率达到80%以上·