从教育传播学看《大学语文》的困境与出路

不容乐观的传播环境,单一重复的传播内容以及陈旧落后的传播手段是造成当下高校“大学语文”日益式微的主要原因,而走出困境也要从这几方面着手进行改革与优化。只有正视现实,坚定信心、端正态度,在优化其传播环境,改进其传播内容、革新其传播方法上积极作为,“大学语文”才能走出困境,告别尴尬。     

高职学院人才培养目标实施方略

高职学院如何办出特色，只有明确培养目标，更新教育观念，强化内部管理，打造高素质的教师队伍，以专业建设为龙头，探索人才培养的新模式，以德育教育为重点，加强学生管理，才能培养出市场适需的高素质应用型人才.     

对体育教育专业篮球普修课教学现状的思考

通过对体育教育专业篮球普修课教学目标、教学内容、教学模式以及对学生的成绩评价进行思考和令尊，结合《全国普通高校学校体育教育本科专业课程方案》对培养目标的规定，提出了对体育教育专业篮球普修课的培养目标进行重新定位，优化教学内容、优化教学模式、优化教学手段、优化评价体系，培养出合格的21世纪体育教师。     

健康第一原则与学校体育教育改革的思考

学校体育立“素质教育”,树“健康第一”的指导思想是新时期学校体育发展的必然走向。但学校体育的健康教育还停留于形式上,还没有完全从原有的模式跳出来。学校体育改革就是要我们去做一种与以往不同但却可以达到以增进健康为主要目的的体育活动。从大众体育健康的角度,忽视或不要去刻意追求过去那种生理“波峰”的传统模式。     

Proopiomelanocortin expression in the skin during induced hair growth in mice

We demonstrate for the first time a hair cycle-dependent gene and protein expression of proopiomelanocortin in mouse skin in vivo. Northern blot detected POMC mRNA with an apparent size of 0.9 kb in anagen but not telogen skin. Western blot emphasized a specific protein of 30–33 kDa recognized by anti -endorphin in late but not early anagen or telogen skin. By immunocytochemistry, -endorphin antigen was localized in the sebaceous gland in a hair cycle dependent manner.     

In vitro protein synthesis and α amylase activity in F cells from hepatopancreas ofPalaemon serratus (Crustacea; Decapoda)

In crustaceans, all the steps in the assimilation of food take place in the hepatopancreas. To facilitate the study of this organ, a method for the dissociation of cell types was developed. The hepatopancreas of the prawnPalaemon serratus was mechanically dissociated and the cells separated by Percoll density-gradient centrifugation. The E and R cells had similar densities of around 1.05 g/ml. The F cells were separated into two distinct fractions with densities of 1.075 and 1.082 g/ml. The B cells sedimented at a density of 1.12 g/ml. The ratio between the two populations of F cells was found to vary during the intermolt cycle while B cells disappeared after the molt. When the density gradient fractions were incubated with³H-leucine, incorporation was highest in the F cell fractions. Measurements of -amylase activity, indicated that the two populations of F cells may be derived from the same cell type.     

Selective protection of cells against X-irradiation. Isoproterenol protects only those cells that possesβ-adrenoreceptors

Summary In mixed culture of Chinese hamster fibroblatst, clone 431, and transformed murine L fibroblasts, clone B-82, isoproterenol was found to protect only 431 cells against ionizing radiation. It was shown that 431 cells, in contrast to B-82 cells, possess-adrenoreceptors, and the radioprotective effect of isoproterenol can be realized only if this agent interacts with-adrenoreceptors coupled with the cAMP system. Since malignization often causes the disappearance of-adrenergic and other hormone receptors, the combined culturing and irradiation of the cells studied can be regarded as a model of the growth of malignant cells (B-82) among normal tissue cells (431 cells) under conditions of radiation therapy. A possibility of selective protection against radiation damage of normal tissue cells, with retention of the former radiosensitivity of tumor cells, is discussed.     

A new semisynthetic ergot peptide alkaloid: DCN 203-922

Summary We report the synthesis, stereochemistry and preliminary pharmacological evaluation of DCN 203-922, a novel ergot alkaloid of the cyclol type, which contains in its peptide moiety the uncommon amino acid L-allo-isoleucine.Part of this paper was reported by this author at the Herbstversammlung der Schweizerischen Chemischen Gesellschaft, Bern, in October 1986.     

Structure of the human CLC-7/Ostm1 complex reveals a novel state

CLC-7 functions as a Cl?/H+ exchanger in lysosomes. Defects in CLC-7 and its β-subunit, Ostm1, result in osteopetrosis and neurodegeneration. Here, we present the cryogenic electron microscopy (cryo-EM) structure of the human CLC-7/Ostm1 complex (HsCLC-7/Ostm1) at a resolution of 3.6 ?. Our structure reveals a new state of the CLC-7/Ostm1 heterotetramer, in which the cytoplasmic domain of CLC-7 is absent, likely due to high flexibility. The disordered cytoplasmic domain is probably not able to restrain CLC-7 subunits and thus allow their relative movements. The movements result in an approximately half smaller interface between the CLC-7 transmembrane domains than that in a previously reported CLC-7/Ostm1 structure with a well-folded cytoplasmic domain. Key interactions involving multiple osteopetrosis-related residues are affected by the interface change.